Gene Information

Name : smpB (Bgr_05830)
Accession : YP_002971582.1
Strain : Bartonella grahamii as4aup
Genome accession: NC_012846
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 712806 - 713282 bp
Length : 477 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAATAAAAAAAAGAACGCGCCCGTACGGAAAATAATTGCTGACAATCGTAAAGCACGTTTTAATTTTGAAATTCTTAA
TAATCTCGAGGCCGGTCTTGTCCTTCAGGGAGCGGAAGTAAAGTCCTTACGTTCTAATCATGCCAATATTGCTGAAAGCT
ATGCGAGTTTTGAGAATGGGGAATTATGGTTAGTAAACAGCTATATTCCTGAATATACGCAGGCTAATCGTTTTAATCAT
GAACCGCGACGTTTGCGCAAGTTATTACTTTCAAAACGTGAGATGGCACGTTTTTTTAATGCAACGTCTCGTGAAGGAAT
GACACTTGTTCCTCTTAAACTTTATTTTAATGAACGAGGGCGTGTTAAGTTGGAGATTGCTCTAGCGCGGGGAAAAAAGC
TTCATGATAAGCGCGAAACGGAAAAAAAACGCGATTGGGGACGTGAAAAAGCAAGACTTTTAAAAAGATATGGATGA

Protein sequence :
MNKKKNAPVRKIIADNRKARFNFEILNNLEAGLVLQGAEVKSLRSNHANIAESYASFENGELWLVNSYIPEYTQANRFNH
EPRRLRKLLLSKREMARFFNATSREGMTLVPLKLYFNERGRVKLEIALARGKKLHDKRETEKKRDWGREKARLLKRYG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-21 49
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 9e-21 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-19 47