Gene Information

Name : nrdF (Bgr_02050)
Accession : YP_002971249.1
Strain : Bartonella grahamii as4aup
Genome accession: NC_012846
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : -
Position : 297281 - 298255 bp
Length : 975 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGACAAAGATTACAACCAAAAATCCTGTTGTGTGCGCTGTTAATTGGAATAGATTACATGATGAGAAAGATCTTGAAGT
ATGGAACCGCTTAACTGGGAACTTTTGGTTACCTGAGAAGGTTCCACTTTCCAATGATATTCCCTCATGGTCAAGCTTAA
CAGATGAAGAACGTAAATTAACAATTCGTGTTTTTACAGGACTAACGCTTTTAGATACAATTCAAAATACTGTTGGAGCC
ATTTCGCTTCTGGCTGATGCAATAACAGAGCATGAGGAGGCAGTGTTGACGAATATTGCTTTCATGGAAGCGGTTCATGC
ACGTTCTTATTCCTCTATTTTTTCAACCCTTTGTTCGACGGTAGAAGTTGATGATGCGTTTAGATGGTCAGAAGAAAATA
TTCATTTGCAGAAAAAGGCTAGATTAGTACTTGAGCGTTATGAAGCAAATGATCCACTTAAGAAAAAAATTGCTTCGACT
TTGCTGGAAAGCTTTTTATTTTATTCTGGTTTTTATTTGCCCATGTATTGGGCCAGTCGCGCTAAGTTGACCAATACAGC
AGATCTCATTCGATTAATCATTCGTGATGAAGCAGTCCATGGTTATTATATAGGTTATAAATTCCAATTGGGCTTTGCAA
AGCTTGATGAAGCCAAAAAGAAAGAAATTAAAGATTTTGCTTTTAACCTGCTCTTTGACCTTTATAATATCGAGTGCAAA
TATACTGAAGATCTTTATGATGCACTTGGATTGACAGAAGATGTTAAAATTTTTCTTCATTATAATGCTAACAAGGCTTT
AATGAATTTAGGTTTTGAAGCTCTTTTTCCCCCTGAGGTTTGTCGTGTTAATCCCGCTATTTTGGCAGCTTTATCACCAA
ACTCTGACGAAAATCATGACTTTTTTTCAGGGGCAGGTTCTTCTTATGTCATTGGCAAGGCGGTTGCTACCACGGATGAT
GATTGGGAATTTTAA

Protein sequence :
MTKITTKNPVVCAVNWNRLHDEKDLEVWNRLTGNFWLPEKVPLSNDIPSWSSLTDEERKLTIRVFTGLTLLDTIQNTVGA
ISLLADAITEHEEAVLTNIAFMEAVHARSYSSIFSTLCSTVEVDDAFRWSEENIHLQKKARLVLERYEANDPLKKKIAST
LLESFLFYSGFYLPMYWASRAKLTNTADLIRLIIRDEAVHGYYIGYKFQLGFAKLDEAKKKEIKDFAFNLLFDLYNIECK
YTEDLYDALGLTEDVKIFLHYNANKALMNLGFEALFPPEVCRVNPAILAALSPNSDENHDFFSGAGSSYVIGKAVATTDD
DWEF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 4e-105 67