Gene Information

Name : guaA (Bgr_01910)
Accession : YP_002971237.1
Strain : Bartonella grahamii as4aup
Genome accession: NC_012846
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 281743 - 283299 bp
Length : 1557 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCATATCACATCCAGATACGGTTCTTATTATTGACTTTGGTTCACAAGTTACACAACTTATTGCACGACGGGTACG
AGCAATGGGGGTATATTGTGAAATTGCTCCTTTTCAATTGGCTTTAGAAGCTGTGCGACGCATAAATCCTAAAGCTATTA
TTTTATCAGGGAGTCCTTATTCCGTTATTGATGAGGGCTCTCCGCGTGCTCCAATGGAAATTTTTGAGGCGGGTATTCCG
ATTCTGGGTATTTGCTATGGGGAACAAGTCATGTGTGTTCAGCTTGGAGGAAAGGTTGAAGCTGGACATGAGCGTGAATT
TGGGCGTGCTTTTTTGGAAGTGCAAGAAGAGAGTGCTCTTTTTGATGGAGTGTGGGAAAAAGGTTCTCGTTATCAAGTAT
GGATGAGCCATGGTGACCGTGTGGCAGCTTTACCAGAAGGTTTTCGTGTCATAGGGACCTCAAACGGAGCTCCTTATGCG
GCTATTGCTGATGAAAAAAGACATTTTTATGCAGTACAGTTTCATCCTGAAGTTATCCATACACCAGATGGTACAAAACT
TTTGCAAAACTTTATTCATAAAATCTCTGCTATTAAAGGTGGTTGGTCAATGGCTTCTTATCGTGAGCAGGCAATTGCTA
CGATACGACAAAAAGTTGGGAAAAGTCGTGTGATTTGTGGTCTTTCAGGGGGGGTAGATTCATCTGTTGTAGCGGTACTC
CTTCATGAAGCCATAGGAGATCAACTGACATGCATTCTGGTAGACCATGGGCTGATGCGCAAGAATGAAGCTGAAGAAGT
TCTCACGCTCTTTCGTGATCATTATAATATAGAGCTTATTCACGTTAATGCTGCCGATATATTTCTTAATGCTTTAGAGG
GTGAGACAGATCCAGAAAAAAAGCGCAAAACGATTGGTCGCCTTTTTATTGAAGTTTTTGAAGAAGAAACTAAAAAAATA
GGAGGTGCAGAGTTCTTAGCACAAGGAACACTTTATCCAGATGTTATTGAGAGTGTATCTGCTATTGGTAAAACGGTAAC
CATTAAAAGCCATCATAATGTGGGTGGGCTGCCAGAACAGATGAATATGCAACTTGTAGAACCGTTGCGTGAGCTCTTTA
AGGATGAGGTTCGCTTGCTAGGGCGAGAGTTAGGATTACCAGAGCAGTTTATTGGTCGCCATCCTTTTCCAGGTCCAGGT
CTTGCAATTCGCTGTCCAGGTACTGTGACCCGTGAAAAATTAGAAATTTTACGTGAAGCAGATGCTATTTATCTTGAGGA
AATCCGTAAAGCCGGTCTTTATAACGAAATTTGGCAAGCTTTTGCTGTTCTTCTTCCTGTTCAAACTGTTGGCGTGATGG
GGGATGGTCGCACTTATGAATTTGTTTGTGCTCTTCGTGCCGTCACATCTGTAGATGGAATGACTGCTGATTTTTATCCC
TATGATATGGCGTTTTTAGGTAAGACGGCAGCACGTATTATTAACGAAGTTAGAGGGATTAATCGTGTTGTATATGATGT
AACTTCAAAGCCTCCTAGTACTATTGAATGGGAATAA

Protein sequence :
MSISHPDTVLIIDFGSQVTQLIARRVRAMGVYCEIAPFQLALEAVRRINPKAIILSGSPYSVIDEGSPRAPMEIFEAGIP
ILGICYGEQVMCVQLGGKVEAGHEREFGRAFLEVQEESALFDGVWEKGSRYQVWMSHGDRVAALPEGFRVIGTSNGAPYA
AIADEKRHFYAVQFHPEVIHTPDGTKLLQNFIHKISAIKGGWSMASYREQAIATIRQKVGKSRVICGLSGGVDSSVVAVL
LHEAIGDQLTCILVDHGLMRKNEAEEVLTLFRDHYNIELIHVNAADIFLNALEGETDPEKKRKTIGRLFIEVFEEETKKI
GGAEFLAQGTLYPDVIESVSAIGKTVTIKSHHNVGGLPEQMNMQLVEPLRELFKDEVRLLGRELGLPEQFIGRHPFPGPG
LAIRCPGTVTREKLEILREADAIYLEEIRKAGLYNEIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADFYP
YDMAFLGKTAARIINEVRGINRVVYDVTSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-140 56
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-140 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-140 56
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-116 50