Gene Information

Name : thyA (Bgr_13730)
Accession : YP_002972269.1
Strain : Bartonella grahamii as4aup
Genome accession: NC_012846
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 1535617 - 1536411 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAAATCTATCTTGATCTTTTATCGCATGTTTTAAATAACGGCATTGATCGTACAGATCGAACCGGTGTGGGGACGCG
ATCAATTTTTGGGTATCAAATGCGGTTTGATTTGCAGGCTGGCTTTCCTCTGTTAACAACGAAGAAATTGCATTTGCGCT
CGATCATTTATGAGCTTTTGTGGTTTTTGAGAGGTGATACAAATATTGCATGGTTGAAGGAACATGGTGTGTCAATTTGG
GATGAGTGGGCTGATGAGAAAGGGAACCTTGGTCCTATTTATGGTTATCAGTGGCGCTCTTGGCCTGCTCCCGATGGACG
GCATATTGATCAAATCAGTCATCTTTTGACGATGATTAAAGAAACGCCTGATTCTCGTCGCTTAATTGTATCTGCTTGGA
ACCCCGCACTGATAGAGGAGATGGCTTTGCCTCCTTGTCATTGTTTTTTTCAATTTTATGTTGCTGATGGGAAGCTATCC
TGTCAGCTTTATCAGCGTTCAGCAGATATTTTCTTAGGTGTTCCGTTTAATATTGCTTCGTATGCGTTGTTGACGATGAT
GATTGCTCAAGTAAGTGGACTTAAAGCAGGAGACTTTATTCATACTCTGGGTGACGCTCATCTTTATTCTAACCATTTTG
AACAGGCGAGATATCAGTTGTCTCGTATACCAAATGCTTTGCCGTTGATGCTTATAAATTCAGCGGTAACAGATCTTTTT
TCTTTTAAATTTGAGGATTTTGAATTGCTTAATTATGAAGCGCAGCCACATATTAAGGCACCGGTAGCAGTATGA

Protein sequence :
MKIYLDLLSHVLNNGIDRTDRTGVGTRSIFGYQMRFDLQAGFPLLTTKKLHLRSIIYELLWFLRGDTNIAWLKEHGVSIW
DEWADEKGNLGPIYGYQWRSWPAPDGRHIDQISHLLTMIKETPDSRRLIVSAWNPALIEEMALPPCHCFFQFYVADGKLS
CQLYQRSADIFLGVPFNIASYALLTMMIAQVSGLKAGDFIHTLGDAHLYSNHFEQARYQLSRIPNALPLMLINSAVTDLF
SFKFEDFELLNYEAQPHIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-79 63