Gene Information

Name : clpB (Balat_1481)
Accession : YP_002970456.1
Strain : Bifidobacterium animalis DSM 10140
Genome accession: NC_012815
Putative virulence/resistance : Virulence
Product : ATP-binding subunit of Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1740976 - 1743663 bp
Length : 2688 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGGAACAGAAATATACGACTTTGGCTCAGGAGGCCTTGGGCGACGCGGTGCAGAGCGCCTCGGCCGCCGGCAACCCGCA
GGTTGAGCCGCTGCATTTGCTTGACTCGCTGCTGCGTCAGGAGAACGGTGTCATCGGTGGTCTCATCGAGGCCGTGGGGG
CGAACAGGCAGACGATCGGCGCGCAGGTGCGCAATGCCCTGGTCTCGCTGCCGAGCGCTTCCGGCTCGTCGACCGCGCAG
GCTTCGGCCAGCCGCCAGCTGACCACCGCGTTGGCCGACGCCAGCAAGGAAATGAAGGACATGGGAGATGAGTACATCTC
CACCGAGCACCTGCTGCTGGGCATTCTCGACGCCGCCCCGAACGAGGCGGCCAAGATTCTCGAGCAGAACGGCATCACGG
CCGACAAGGTGCGCGCGGCCATCCCGAACGTGCGCGGTGGCGCCAAGGTGACGAGCCCGGACGCCGAGGCCTCGTACAAG
GCGTTGGAGAAGTTCTCCACCGACCTGACGGCCCGTGCCCGTGAAGGCAAGCTCGACCCGGTGATCGGCAGGGATCAGGA
GATCCGCCGTGTGATCCAGATTCTGAGCCGCCGCACGAAGAACAACCCGGTGCTGATCGGCGAGCCAGGCGTGGGCAAGA
CCGCCGTCGTGGAAGGCCTCGCCGAGCGCATCGTGGCCGGCGACGTGCCGAGCACACTGCAGAACAAGCGCCTCATCAGC
CTCGACCTGGGCTCCATGGTGGCCGGGTCCAAGTACCGCGGCGAATTCGAGGAACGCCTCAAGGGCGTGCTTGACGAGAT
CAAGCAGTCCGACGGCCAGATCATCACCTTCATCGACGAGATCCATACGATCGTCGGTGCCGGTGCGGCCGAAGGCTCGA
TGGACGCGGGCAATATGCTCAAGCCTATGCTGGCCCGTGGCGAACTGCGCCTGATCGGCGCCACCACGCTCGACGAATAC
CGTGAGAACATCGAGAAGGATCCGGCCCTGGAGCGTCGTTTCCAGCAGGTGTTCGTGGGCGAGCCGAGTGTGGAGGACAC
GATCGCCATTCTGCGTGGCCTGAAGCAGCGCTATGAGGCCCACCACAAGGTGACGATCGGCGACGACGCGCTCGTGGCCG
CCGCAACCCTCTCGAACCGCTACATCACCGGTCGTCAGCTGCCCGACAAGGCCATCGACCTGGTGGACGAGGCCGCTGCG
CACCTGCGCATGGAACTCGACTCGCAGCCCGAGGAGATCGACGAGCTGCAGCGCAAGGTGACGCGCCTCGAAATGGAGGA
GATGCAGCTGAAGAAGGCCGAGGACCCGGCCTCCAAGGAGCGCCTCGCCAAGCTCCAGAGCGAACTGGCCGACGCCCGCG
AGAAGCTCGCAGGACTCAACGCCCGTTGGAACGCCGAGAAGGAAGGCCACAACAAGGTCGGCGACCTGCGTGCGCAGCTC
GACGAGAAGCGCGTCGAGGCCGACAAGGCCACGCGTGAAGGCGACCTGGCGAAGGCGAGCCGCATTCTGTACGGTGAGAT
CCCGGCCATTCAGAAGCAGCTGACCGAAGCCGAGCACGAGGCCGAGAAGGAAGCCGACTTCGCCCATGAGGATGAGCCCA
TGGTCCCCGACCATGTGGACGCCGATTCGGTGGCCGGCATCGTCTCCGAATGGACCGGCATTCCGGTCGGCCGTCTCATG
CAGGGCGAGAACGAGAAACTGCTCAACATGGAGGAATACCTCAACAGGCGCGTGATCGGCCAGCCGGAAGCCGTTCGTGC
GGTCTCCGACGCCGTGCGCCGTTCGCGTGCAGGCCTGTCCGACCCGAATCGCCCGACCGGTTCGTTCCTGTTCATGGGCC
CGACCGGCGTGGGCAAGACCGAGCTCGCCAAGGCGCTCGCCGAATTCCTGTTCGACGACGAGAAGGCCATGATCCGCATC
GACATGTCGGAGTACATGGAGAAGTCGTCGGTCTCGCGTCTCATCGGCGCAGCCCCGGGCTATGTCGGTTACGAGGAGGG
CGGCCAGCTCACCGAGGCCGTGCGTCGTCGTCCGTATTCGGTGGTGCTGTTCGACGAGGTGGAGAAGGCCAATTCCGAGG
TCTTCGACATTCTGCTGCAGGTGCTCGATGACGGCCGCCTGACCGATGGTCAGGGCCGCACCGTGGACTTCAAGAACACG
ATCCTGATCATGACGTCGAACCTCGGCTCGCAGTTCCTGGTCAACCCCGACCTGGATGAGCAGCAGAAGAAGGACGCCGT
GATGAACGCGGTGCACAGCCAGTTCCGTCCGGAGTTCCTCAACCGTCTCGACGACATGGTGATCTTCCACCCGCTCACAC
GCCAGGAGCTCGGCAAGATCGTCGACCTGCAGGTCAAGCAGGTGGCTTCGCGCCTCACCGACCGTCGCATCACGCTCGAC
GTCACCGAAGCGGCACGCGAATGGCTTGCCGACACCGGCTACGACCCGGCATACGGTGCGCGTCCGCTGCGCCGTCTGGT
GCAGACCGAGGTGGGCGACCAGCTGGCACGCATGCTGCTCGCCGGCGAGATCAAGGACGGTGACACCGTGCTGGTGGACC
ACACCGGTGGCGAGCACCTCGAGCTCACCGACCATACGCACAACCCGATGGAAGGCGACCCGAACCCTGGAGACTCCCAG
ATCACGGTTGACGACAAGAAGGATGACGGCGAACAGAAGGACGCCTGA

Protein sequence :
MEQKYTTLAQEALGDAVQSASAAGNPQVEPLHLLDSLLRQENGVIGGLIEAVGANRQTIGAQVRNALVSLPSASGSSTAQ
ASASRQLTTALADASKEMKDMGDEYISTEHLLLGILDAAPNEAAKILEQNGITADKVRAAIPNVRGGAKVTSPDAEASYK
ALEKFSTDLTARAREGKLDPVIGRDQEIRRVIQILSRRTKNNPVLIGEPGVGKTAVVEGLAERIVAGDVPSTLQNKRLIS
LDLGSMVAGSKYRGEFEERLKGVLDEIKQSDGQIITFIDEIHTIVGAGAAEGSMDAGNMLKPMLARGELRLIGATTLDEY
RENIEKDPALERRFQQVFVGEPSVEDTIAILRGLKQRYEAHHKVTIGDDALVAAATLSNRYITGRQLPDKAIDLVDEAAA
HLRMELDSQPEEIDELQRKVTRLEMEEMQLKKAEDPASKERLAKLQSELADAREKLAGLNARWNAEKEGHNKVGDLRAQL
DEKRVEADKATREGDLAKASRILYGEIPAIQKQLTEAEHEAEKEADFAHEDEPMVPDHVDADSVAGIVSEWTGIPVGRLM
QGENEKLLNMEEYLNRRVIGQPEAVRAVSDAVRRSRAGLSDPNRPTGSFLFMGPTGVGKTELAKALAEFLFDDEKAMIRI
DMSEYMEKSSVSRLIGAAPGYVGYEEGGQLTEAVRRRPYSVVLFDEVEKANSEVFDILLQVLDDGRLTDGQGRTVDFKNT
ILIMTSNLGSQFLVNPDLDEQQKKDAVMNAVHSQFRPEFLNRLDDMVIFHPLTRQELGKIVDLQVKQVASRLTDRRITLD
VTEAAREWLADTGYDPAYGARPLRRLVQTEVGDQLARMLLAGEIKDGDTVLVDHTGGEHLELTDHTHNPMEGDPNPGDSQ
ITVDDKKDDGEQKDA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 5e-164 46
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-109 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 3e-110 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 2e-110 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_002970456.1 ATP-binding subunit of Clp protease VFG2084 Protein 2e-112 44
clpB YP_002970456.1 ATP-binding subunit of Clp protease VFG2076 Protein 5e-121 42