Gene Information

Name : leuS (Balac_0754)
Accession : YP_002968186.1
Strain : Bifidobacterium animalis Bl-04
Genome accession: NC_012814
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 885229 - 888120 bp
Length : 2892 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCCCAGCGCATTGAGGAGAAATGGCAGGACATCTGGGAGAGCGAGGGCACGTTCTGGGCCGCGAACGTGAGCGGCGA
ACTCACTGACAGCAAGGGACGTCATGCCGATGGCCGTCAGTCCTTCTTCGCCATGGACATGTTCCCCTACCCTTCGGGCA
AAGGATTACATGTCGGTCATCCGTTGGGATATCTGGCCACCGATGTGGTGAGCCGATACCATCGCATGAAGGGCGAGAAC
GTCCTGCACGCCATGGGCTATGACGCATTCGGGCTTCCCGCCGAACAGTATGCCGTGCAGACGGGCCAGCACCCGCGCAT
CACGACCGAACAGAACATCGCGAATATGCGGCGACAGTTGCGCCGCATGGGGCTGAGCTTCGACGACCGCCGCTCCTTCG
CCACGATCGAACCGGAATACGTGCGTTGGACCCAATGGATCTTCTCACGCATCTACGATGCCTGGTACGATCCGGATACG
AGAAATCCGAGTGGATCCATGGGGTGCGCGCGCCCGATTTCCACCCTGATCGGACAATTCCGCGCCGGCACACGTCCGAT
TGACGGACATGAGGACAAGGCCTGGGATGAACTCACCGAGATGGAGCAGACCGAGGTGCTCAATGAGTACCGACTCGCCT
ACATCTCCAAATCGCCTGTCAATTGGTGCCCTGGGCTTGGCACGGTGCTCGCCAATGAGGAGGTCACTGCAGAGGGGCGT
TCCGAACGTGGCAATTTCCCGGTGTTCCAGCGTGAGCTTCGTCAGTGGTCGATGCGCATCACCGCATACGGGCATCGTCT
CATAGAGGATCTCGATTCCATCGACTGGCCTGAGAAGGTCAAGCTCATGCAGCGCAACTGGATCGGGGAGTCGCATGGCG
CCTCCGTGCATTTCAAGGTGCCGGTCGACGGTGAGATGGCAGATATGGAGATCTACACCACACGACCCGACACGTTGTTC
GGTGCCACGTTCTGTGTGGTCTCTCCCGAACACCCGATGCTGGAGCATGTGCCCCAATCCTGGCCGGAAGGTGTGGACCC
GGCGTGGACGGGTGGCTATGCCACGCCGAGCGAGGCCGTATCCGCATACCGTGAGCTCGCGGAGGCAAAGACCGCGGCCG
ACCGTGTGGCCGACAACGGTGAGAAGACGGGTTTGTTCACCGGCCTGTACGCGATCAACCCGATCACCGGTGCCAAGCTG
CCGGTGTTCACGGCCGACTATGTGCTCATGGACTATGGTACCGGTGCCATCATGGCCGTTCCGGGCGGTGACCAGCGAGA
CTACGATTTCGCCGTCAAGTACGGTCTTCCGGTGATCTACACGGTTGCGCCGCTCCCTGATTCCGGTGACGATCTGGCCA
ATTATGAGGGTACCGCCCCGTTCGTTTCGCATGACGGCATCGTCATCAATTCAGCCGTCGACGCGACGTGGGCCCGTGGC
GACGCGCTCTGCCTTGACGGCATGCGTGTGGATGATGCGATTGCTGCCGTCACCACGTGGCTCGAGGAGGCCCAGGTGGG
CAAGGGGGCCACGAGCTACCGTCTGCGCGACTGGCTCTTCAGCCGCCAACGGTATTGGGGTGAGCCGTTCCCGATTGTCT
ACGATGAGCATGAGGTGCCCCATCTGGTGCCCGACAGCATGCTGCCCATCAATCTGCCCGACGTTCCGGATTACAGCCCC
AAGACCTTCGACCCGGAGGATTCCCAGTCGAGTCCGGAGGCCCCGTTGAGCCGCAACGAGGATTGGGTGAATGTCACGCT
CGATCTCGGTGACGGTCCGAAGACCTACCATCATGACACGAACACGATGCCGAATTGGGCTGGTTCCTGCTGGTACTACA
TGCGTTACCTCAATCCCCATGACACCGAGCACATGGTGGAGCGCGACGAATACGACTATTGGATGGGTCCGAAGCACTCC
CCGGCGGCCGGGCAGGCCGGAGGCGTCGATCTGTATGTGGGCGGCGTGGAGCACGCGGTGCTACATCTGCTCTACTCACG
GTTCTGGCATAAGATCCTGTTCGACCTGGGGTACGTGGATTCGTTCGAACCGTTCCACAAGCTTTTCAACCAAGGCATGA
TCCAAGCGTATGCCTACACCGATGACCGCGGTCAGTATGTGCCGGCCGAGGACGTTCAGGAGAGCGAAGTGGACGGCAAG
ACCGTGTACACCTACGAAGGCGAACCGGTCAACCGTGAGTTCGGCAAGATGGGCAAGAGCCTCAAGAACATCGTGACCCC
GGACTACATGTACGACCATTACGGCGCAGACACATTCCGCCTCTATGAGATGAGCATGGGACCGCTTGACGAGTCACGTC
CATGGAACACCCGCAATGTGGTGGGCGGCATGCGATTCCTGCAGCGTTTGTGGCGCAATGTGATTGATGAGAACACCGGC
GAGGTCACGGTGACCGACGACGCGATGGACGAACGTACGTTGAAACTGCTCAACAATACGATCGCCGAGGTGACCGGTGA
GATGGAGGCCATGCGTCCAAACACCGCCATCGCCAAACTCATCGTGCTCAACAATCACCTGACCGGCATGAACGGCGTGC
CCCGCGCCGCCGTGGAGCCGCTGGTGCTCATGGTGGCTCCGATCGCACCGCATATAGCCGAGGAGCTGTGGAACCGGCTC
GGCCATGATGAGTCGTTGGCCCACCATCCATGGCCACAGGCCGACGAGCGTTATGTTGGGCAGGACACCGTCACCGCCGT
GGTGCAGATCAAAGGCAAGGTGCGGGCCAAACTCGAGGTGAGTGCCGACATCGACCCGGATGAACTGGAGAAGATGGCCT
TGGAGGCTGTGGCTGAGCGTCTTGGAGGCAAGCCGCCGCGCAAGGTGATCGTCAAGGCCCCGAAGATTGTTTCGATCGTC
CCGGGCGAATGA

Protein sequence :
MAQRIEEKWQDIWESEGTFWAANVSGELTDSKGRHADGRQSFFAMDMFPYPSGKGLHVGHPLGYLATDVVSRYHRMKGEN
VLHAMGYDAFGLPAEQYAVQTGQHPRITTEQNIANMRRQLRRMGLSFDDRRSFATIEPEYVRWTQWIFSRIYDAWYDPDT
RNPSGSMGCARPISTLIGQFRAGTRPIDGHEDKAWDELTEMEQTEVLNEYRLAYISKSPVNWCPGLGTVLANEEVTAEGR
SERGNFPVFQRELRQWSMRITAYGHRLIEDLDSIDWPEKVKLMQRNWIGESHGASVHFKVPVDGEMADMEIYTTRPDTLF
GATFCVVSPEHPMLEHVPQSWPEGVDPAWTGGYATPSEAVSAYRELAEAKTAADRVADNGEKTGLFTGLYAINPITGAKL
PVFTADYVLMDYGTGAIMAVPGGDQRDYDFAVKYGLPVIYTVAPLPDSGDDLANYEGTAPFVSHDGIVINSAVDATWARG
DALCLDGMRVDDAIAAVTTWLEEAQVGKGATSYRLRDWLFSRQRYWGEPFPIVYDEHEVPHLVPDSMLPINLPDVPDYSP
KTFDPEDSQSSPEAPLSRNEDWVNVTLDLGDGPKTYHHDTNTMPNWAGSCWYYMRYLNPHDTEHMVERDEYDYWMGPKHS
PAAGQAGGVDLYVGGVEHAVLHLLYSRFWHKILFDLGYVDSFEPFHKLFNQGMIQAYAYTDDRGQYVPAEDVQESEVDGK
TVYTYEGEPVNREFGKMGKSLKNIVTPDYMYDHYGADTFRLYEMSMGPLDESRPWNTRNVVGGMRFLQRLWRNVIDENTG
EVTVTDDAMDERTLKLLNNTIAEVTGEMEAMRPNTAIAKLIVLNNHLTGMNGVPRAAVEPLVLMVAPIAPHIAEELWNRL
GHDESLAHHPWPQADERYVGQDTVTAVVQIKGKVRAKLEVSADIDPDELEKMALEAVAERLGGKPPRKVIVKAPKIVSIV
PGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-138 45