Gene Information

Name : nhaA (MexAM1_META2p1135)
Accession : YP_002967248.1
Strain :
Genome accession: NC_012811
Putative virulence/resistance : Unknown
Product : pH-dependent sodium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3004
EC number : -
Position : 1063853 - 1065067 bp
Length : 1215 bp
Strand : +
Note : exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH

DNA sequence :
GTGTCGTTGCAGTCCCGCGTCGTTTCCTCGCGTGTCCGCCCCGTGTCGGCCCTGCGCACCTTGCTGACCGGCGAAGCCGG
CGGCGGTCTCCTCCTGATGGCGAGCGCGGCGCTTGCGCTGGCGGTGGCGAACTCGCCTTTCGCCGGCACCTACTTCGCTG
TGCTGAAGGCCTATCTCGGCCCGCTCTCGGTGCTGCACTGGATCAACGACGCCCTGATGGCGGTGTTCTTCCTGCTCGTC
GGCTTGGAGATCAAGCGCGAGATGCTGGACGGGCAGTTGCGCACTTGGCCCGACCGGGCGCTGCCCGGCCTCGCCGCGCT
GGGCGGCATGGCGGCGCCAGCCCTGGTCTACGCTGCAGTAAACTGGCACTCGCCCGAGACCCTACGCGGCTGGGCGATCC
CGGCCGCCACCGACATCGCCTTCGCGCTCGGCGTGCTGGCGCTGCTGGGATCGCGCGTGCCGGTCTCGCTCAAGGTGTTC
CTGACGGCGCTCGCCATCATCGACGACCTCGGCGCGGTGCTTATCATCGCCCTGTTTTACACCGCCGACCTGTCGCTGCC
GATACTGGGCGGGGCGGCCGCCACGCTCGCGGTGCTCTACGGGCTGAACAAGGCCGGCGTGGTTCGGCTCTGGCCCTACC
TCGTGCTCGGCATCGTCCTCTGGTTCTTCGTGCTGAAGTCAGGTGTGCACGCCACGGTGGCGGGCGTGCTACTGGCCATG
ACCATCCCGCTCCGGCTGAGCGTCGGCAGGCCGGACGACCCGACCTCGCCGCTGCACATCCTCGAACACGCGATCCATCC
CTGGTCGGCCTACCTGATCCTGCCGGTCTTCGGATTCGCCAACGCCGGCGTGTCGCTCGCGGGCTTCAACCCCCACATGC
TGCTCGACCCGGTGACGCTCGGCGTCGCGCTGGGGCTGCTCGTCGGCAAGCAGGTCGGCGTGTTCGGCTTCGTGCTCGCC
GCAGTGAAGCTCGGGCTGGCGCAGCGGCCGGCCCATGCAGGTTGGGGGCAGGTTTATGGCGTCTCGCTCCTGTGCGGCGT
CGGCTTCACCATGAGCCTGTTCATCGGCCTGCTCGCCTTCGCGAACTCGCCCGCGCTGGAAGCCGAGGTCAAGGTCGGCG
TGCTCGCCGGCTCCATCGCCTGCATGCTGGCTGGTGCGTTCGTGCTGCTGGTCGCGCCCGTGGCGGAGCGGAACCGGGAC
CATACGGCGGAATGA

Protein sequence :
MSLQSRVVSSRVRPVSALRTLLTGEAGGGLLLMASAALALAVANSPFAGTYFAVLKAYLGPLSVLHWINDALMAVFFLLV
GLEIKREMLDGQLRTWPDRALPGLAALGGMAAPALVYAAVNWHSPETLRGWAIPAATDIAFALGVLALLGSRVPVSLKVF
LTALAIIDDLGAVLIIALFYTADLSLPILGGAAATLAVLYGLNKAGVVRLWPYLVLGIVLWFFVLKSGVHATVAGVLLAM
TIPLRLSVGRPDDPTSPLHILEHAIHPWSAYLILPVFGFANAGVSLAGFNPHMLLDPVTLGVALGLLVGKQVGVFGFVLA
AVKLGLAQRPAHAGWGQVYGVSLLCGVGFTMSLFIGLLAFANSPALEAEVKVGVLAGSIACMLAGAFVLLVAPVAERNRD
HTAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nhaA1 YP_001220808.1 NahA family Na(+)/H(+) antiporter Not tested chp/tomA region Protein 4e-32 41