Gene Information

Name : ureC (MexAM1_META1p0976)
Accession : YP_002962148.1
Strain : Methylobacterium extorquens AM1
Genome accession: NC_012808
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 1012472 - 1014184 bp
Length : 1713 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 8288539; Product type e : enzyme

DNA sequence :
ATGGTCACGATCCCAAGGCGCGATTACGCCGCCCTCTACGGCCCCACCACCGGCGACGGCGTGCGGCTCGCCGACACCTC
TCTCATCGCGGTGGTCGAGCACGACCACGCAGTCTACGGCGACGAGTGCCTGCATGGCGGCGGCAAGACTCTTCGGGATG
GCATCGGGCTCGCGCCCGGCGTCACGGCGGCGCAGGGCGCGCTCGATTTCCTGCTGTGCAATGTCCTCGTGATCGATCCC
GTCCTCGGCATCGTGAAGGGCGATCTCGGCATCAAGGACGGGCGCATCGTCGGCCTCGGCAAGGCTGGCAACCCGGCGAT
CATGGACGGCGTCGATCCGCGCCTGATCGTGTCGGCCGGCACCACGGTGCGCGACTGCGAGGGGCTGATCGCGACGCCCG
GCGCCATCGACGTTCACGTGCACTTCGATTCCGCCGGCCTGCCCGACCACGCCATCGCCTCAGGGATCACCACCCTGCTC
GGCGGCTCGCTCGGGCCGATCACCGTCGGCATCGATTCCGGCGGGCCGTTCAACACGGGGAAAATGCTCCAGGCGGCGGA
AGCCTGGCCCGTCAATTTCGGCTTTTTGGGAAGGGGCAACACCCACAAGCCGGCAGCCTTGAAGGAACAGCTAGAAACCG
GCGTCCTTGGCCTCAAGATCCACGAGGATTGGGGGGCGATGCCGGCGGCGATCGATGCCTGCCTCGGCTTTGCCGACGAA
TACGACTTCCAGGTCCAGCTGCACACCGACACGCTCAACGAGTCGGGCTTCGTGGAGGACACGCTGGCCGCGATCGGCGG
CCGCACGATCCACATGTACCACACCGAGGGCGCGGGCGGCGGGCACGCGCCCGACATCATCCGCGTGGCGGGGCTGCCCC
ACTGCCTGCCCTCCTCGACGAACCCGACCAATCCCTACACGGTCAACACGTTCGACGAGCACCTCGACATGACGATGGTG
TGCCACCACCTCAACCCGGCTTTGCCGGAGGATGTAGCGTTTGCCGAGAGCCGCATCCGGGCGCAGACCATCGCGGCCGA
GGACGTGCTGCACGATATCGGCGCGATCTCGATGCTCGGCTCCGACAGCCAGGGCATGGGCCGCATCCACGAGGTGATCT
GTCGGACATGGCAGCTCGCCTCCAAGATGAAGGACCAGCGCGGCGCCCTGCCGGAGGAGCGGCCGGGCTTCGGCGACAAT
GCCCGGATCAAGCGCTACATCGCCAAATACACGATCAACGCCGCGCGCACTTTCGGCATCCAAGAGCATATCGGCTCGCT
GGAGCCCGGCAAGATGGCCGACATCGTGATCTGGCGCCCGGCCTTCTTCGGCATCAAGCCGGAACTCGTGATCAAGGGCG
GCTTCATCGCCTGGGGCGCCATGGGCGATTCCGCGGCCTCCCTGATGACCTGTGAGCCGATGCTGATGCGCCCGCAATGG
GGCGCGTTCGGGCTGGCCAAGCAGGGCCTGTCGGCCTGCTTCGTCCACCCGCTCGCCATCGAAGGGGGACTGCGCGAGAG
CCTTGGCCTTCGCAAAGGCCTGCTGCCGGCCCGCGGCACCCGCACGCTGACCAAAGCCGACATGCTCTGGAACGACGCCT
GCCCGGATATCCGGGTCGATCCGCAGACCTTCGAGGTCTTCGTGGACGGGGAACTCGCCACCTGCGAGCCCGCCACCGTC
CTCCCGCTCGCCCAACGCTACATGCTGCGATGA

Protein sequence :
MVTIPRRDYAALYGPTTGDGVRLADTSLIAVVEHDHAVYGDECLHGGGKTLRDGIGLAPGVTAAQGALDFLLCNVLVIDP
VLGIVKGDLGIKDGRIVGLGKAGNPAIMDGVDPRLIVSAGTTVRDCEGLIATPGAIDVHVHFDSAGLPDHAIASGITTLL
GGSLGPITVGIDSGGPFNTGKMLQAAEAWPVNFGFLGRGNTHKPAALKEQLETGVLGLKIHEDWGAMPAAIDACLGFADE
YDFQVQLHTDTLNESGFVEDTLAAIGGRTIHMYHTEGAGGGHAPDIIRVAGLPHCLPSSTNPTNPYTVNTFDEHLDMTMV
CHHLNPALPEDVAFAESRIRAQTIAAEDVLHDIGAISMLGSDSQGMGRIHEVICRTWQLASKMKDQRGALPEERPGFGDN
ARIKRYIAKYTINAARTFGIQEHIGSLEPGKMADIVIWRPAFFGIKPELVIKGGFIAWGAMGDSAASLMTCEPMLMRPQW
GAFGLAKQGLSACFVHPLAIEGGLRESLGLRKGLLPARGTRTLTKADMLWNDACPDIRVDPQTFEVFVDGELATCEPATV
LPLAQRYMLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 8e-127 56
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 8e-127 56
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-139 54
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-139 54
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 8e-139 54
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-139 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_002962148.1 urease subunit alpha VFG0270 Protein 1e-127 51