Gene Information

Name : fliI (MexAM1_META1p0589)
Accession : YP_002961796.1
Strain : Methylobacterium extorquens AM1
Genome accession: NC_012808
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 622035 - 623390 bp
Length : 1356 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type e : enzyme

DNA sequence :
ATGACGCAGGAGCGCGGCTCCGGAGGGCTGGCGGCGGCACTCGCCGCGCTCTCGACCGTCGAGACCCTCGAGACCTTCGG
CCGGGTGACGGCGATCCGCGGCCTTCTGGTCGAGGTCGCCGGGCCGGTTTCCGCGATGCGGCTCGGCGGTCGCATCGACG
TGGTGGTGGAGGGCGCCGGCGTCGCGGCCTCGACGGTGCCGTGCGAGGTGATCGGCTTTGCCGGCGACCGCGCGCTCGCC
ATGCCGTTCGGCTCGCTGGAGGGGGTGCGCCGCGGCTGTCCGGCTCTGGTACGCGACGAGGCGGCGGGCGCGATCCGCCC
CTCCGCCGCTTGGCTCGGTCGTACCGTCGATGCCCTCGGGCGCCCGATCGACGGCCTCGGCCCCCTCGCGCAGGGGCCCG
CGATTTATCCCCTGCGGGCCGACCCGCCCCCCGCGCACGGACGACGGCGCGTCGGGCCGCCGCTCGATCTCGGGGTTCGC
TGTATCAACACCTTTCTCACTATGTGCCGCGGGCAGCGCATGGGCATCTTCGCCGGCTCCGGCGTCGGCAAGTCGGTGCT
GCTCTCGATGCTGGCCCGCTACACCGCCGCCGACGTGGCGGTGATCGGCCTCGTCGGCGAGCGCGGCCGCGAGGTTCAGG
AGTTTCTCCAGGACGACCTCGGCGCGGCGGGGCTCGCCCACTCGGTCGTGGTGGTGGCGACCTCCGACGAGCCGGTGCTG
ATGCGCCGCAACGCCGCCTACGTGACCCTGGCGGTGGCCGAGTACTTTCGCGATCAGGGCGCGCAGGTCTTGTGCATGAT
CGATTCGATCACCCGCTTCGCCATGGCCCAACGCGACATCGGGCTGGCCGGCGGCGAGCCCCCGACCGCCAAGGGCTACA
CCCCCACCGTCTTCTCCGAATTGCCGCGCCTGCTCGAACGGGCCGGGCCGGGGGTGGGGGAGGGGGCGATCTCCGGCCTG
TTCACCGTGCTGGTGGAGGGCGACGACCACAACGAGCCGGTGGCGGATGCGGTGCGCGGCATCCTCGACGGGCACATCGT
CATGGAGCGGCGCATTGCCGAGCAGGGGCGCTACCCGGCGATCAACGTGCTGCGCTCGGTCTCGCGCACCATGCCGCGGG
CCTGCGACCCGGCCCACCTCCCCACCGTCCGCCGTGCGCGAAAGGTGCTGGCGACCTATGCCGACATGGAAGAGCTGATC
CGGCTCGGGGCCTACCGTGCCGGTTCCTCGCCGGAGGTGGACGAAGCGGTGGCTCTCATGCCCGATCTGACGGCTTTTCT
GGGGCAGGGTAAGGAAGAAGCAACCTCCATCAGCGAGGGTTATGACCGGTTGGCCGCCATTGTCGGCGGTGCGTGA

Protein sequence :
MTQERGSGGLAAALAALSTVETLETFGRVTAIRGLLVEVAGPVSAMRLGGRIDVVVEGAGVAASTVPCEVIGFAGDRALA
MPFGSLEGVRRGCPALVRDEAAGAIRPSAAWLGRTVDALGRPIDGLGPLAQGPAIYPLRADPPPAHGRRRVGPPLDLGVR
CINTFLTMCRGQRMGIFAGSGVGKSVLLSMLARYTAADVAVIGLVGERGREVQEFLQDDLGAAGLAHSVVVVATSDEPVL
MRRNAAYVTLAVAEYFRDQGAQVLCMIDSITRFAMAQRDIGLAGGEPPTAKGYTPTVFSELPRLLERAGPGVGEGAISGL
FTVLVEGDDHNEPVADAVRGILDGHIVMERRIAEQGRYPAINVLRSVSRTMPRACDPAHLPTVRRARKVLATYADMEELI
RLGAYRAGSSPEVDEAVALMPDLTAFLGQGKEEATSISEGYDRLAAIVGGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 7e-79 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-78 48
lscN AAO18044.1 LscN Virulence TTSS locus Protein 3e-80 46
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 9e-79 46
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-79 46
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-79 46
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 2e-70 46
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-68 46
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 5e-68 46
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-77 45
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-76 45
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-76 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-77 45
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 1e-65 45
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-65 45
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-65 45
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 2e-65 44
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-65 44
escN AAK26715.1 EscN Virulence LEE Protein 1e-68 44
ECs4568 NP_312595.1 EscN Virulence LEE Protein 7e-69 44
escN AAL57542.1 EscN Virulence LEE Protein 1e-68 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 6e-69 44
escN CAI43874.1 EscN protein Virulence LEE Protein 5e-69 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 3e-69 44
escN AAC31513.1 L0034 Virulence LEE Protein 5e-69 44
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 5e-69 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 4e-69 44
escN AAC38383.1 EscN Virulence LEE Protein 2e-69 44
escN YP_003223475.1 translocator EscN Virulence LEE Protein 7e-69 44
escN NP_290268.1 hypothetical protein Virulence LEE Protein 7e-69 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-57 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-57 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-57 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-57 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-61 42
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 7e-63 42
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-63 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-66 42
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 9e-60 41
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 6e-62 41
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_002961796.1 flagellum-specific ATP synthase VFG2499 Protein 3e-85 51
fliI YP_002961796.1 flagellum-specific ATP synthase VFG2144 Protein 2e-83 48
fliI YP_002961796.1 flagellum-specific ATP synthase VFG0048 Protein 4e-82 48
fliI YP_002961796.1 flagellum-specific ATP synthase VFG1254 Protein 3e-86 47
fliI YP_002961796.1 flagellum-specific ATP synthase VFG0390 Protein 1e-81 47
fliI YP_002961796.1 flagellum-specific ATP synthase VFG2331 Protein 7e-82 46
fliI YP_002961796.1 flagellum-specific ATP synthase VFG0192 Protein 2e-80 46
fliI YP_002961796.1 flagellum-specific ATP synthase VFG0515 Protein 7e-66 45
fliI YP_002961796.1 flagellum-specific ATP synthase VFG0730 Protein 1e-69 44
fliI YP_002961796.1 flagellum-specific ATP synthase VFG0812 Protein 3e-69 44
fliI YP_002961796.1 flagellum-specific ATP synthase VFG0555 Protein 5e-58 44
fliI YP_002961796.1 flagellum-specific ATP synthase VFG2459 Protein 2e-61 41