Gene Information

Name : aldA (MexAM1_META1p3652)
Accession : YP_002964640.1
Strain : Methylobacterium extorquens AM1
Genome accession: NC_012808
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3795059 - 3796582 bp
Length : 1524 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9511738; Product type e : enzyme

DNA sequence : 
ATGAACAAGCCCGAATTCCTGGCGGATGCCAAGACGAAGTCGCCGTTTTCGGCGCGCTACGACAACTTCATCGGCGGCCA
GTGGGTCGCGCCGGCGAGCGGCCGCTACTTCGAGAACACCTCCCCCATCACCGGCAAGGTGATCTGCGAGGTCGCCCGCT
CCGAGGCGGCGGACATCGAGCGGGCGCTCGACGCCGCGCACGCCGCCAAGGATGCCTGGGGCCGCACCGCGCCGGCCGAG
CGCGCCCGCATCCTCAACAAGATCGCCGACCGGATGGAGGACAACCTCGATCTGATCGCGCTGGCCGAGACCTGGGACAA
CGGCAAGCCGATCCGCGAGACCACCGCCGCGGACATCCCGCTCGCCATCGACCACTGGCGCTACTTCGCCAGTTGCGTCC
GCGCCCAGGAAGGCGCGATCTCCGAGATCGACCACGACACGGTAGCCTACCACTTCCACGAGCCGCTCGGCGTCGTCGGC
CAGATCATCCCGTGGAACTTCCCGATCCTGATGGCGGTGTGGAAGCTGGCTCCCGCGATCGCCGCCGGCAACTGTGTGGT
GCTCAAGCCCGCCGAGCAGACCCCCGCCTCGATCCTCGTGGTGATGGAGCTGATCGGCGACCTGCTGCCGCCCGGCGTCA
TCAACGTCGTCAACGGCTTCGGCCTGGAGGCCGGCAAGCCGCTCGCCTCGAACCCGCGCATCGCCAAGATCGCGTTCACC
GGTGAGACGACCACCGGCCGCCTCATCATGCAGTACGCCTCGCAGAACCTGATCCCGGTGACGCTGGAGTTCGGCGGCAA
GTCGCCGAACATCTTCTTCGGGGATGTCGTCAACGAGGACGACGACTTCTTCGACAAGGCGCTCGAAGGCTTCACCATGT
TCGCCCTCAACCAGGGCGAAGTCTGCACCTGCCCGAGCCGCGCGCTCGTGCACGAGTCGATCTACGACCGCTTCATCGAG
CGCGCGATCAAGCGCGTCGAGGCGATCACCCAGGGCTCGCCGCTCGATCCGGCCACGATGATCGGCGCGCAGGCCTCTTC
GGAGCAGCTCGAGAAGATCCTCAGCTACGTCGATATCGGCCGCCAGGAAGGCGCCGAGTGCCTCACGGGCGGCGCCCGCG
GCACCCGCGAGGGCGATCTGGCCGACGGCTTCTACATGCAGCCGACGGTGTTCAAGGGCCACAACAAGATGCGGATCTTC
CAGGAGGAGATCTTCGGGCCCGTCCTCTCGGTGACGACCTTCAAGGACGACGAGGAAGCGCTCGCCATCGCCAACGACAC
GCTCTACGGCCTCGGCGCCGGCGTGTGGACCCGCGACGGAACCCGCGCCTACCGCTTCGGCCGCGCCATCCAGGCCGGCC
GCGTCTGGACGAACTGCTACCACGCCTACCCGGCGCACGCGGCCTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGTGAG
ACCCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACATGCTGGTCAGCTACTCCTCGAAGAAGCTCGGGTTCTT
CTAA

Protein sequence : 
MNKPEFLADAKTKSPFSARYDNFIGGQWVAPASGRYFENTSPITGKVICEVARSEAADIERALDAAHAAKDAWGRTAPAE
RARILNKIADRMEDNLDLIALAETWDNGKPIRETTAADIPLAIDHWRYFASCVRAQEGAISEIDHDTVAYHFHEPLGVVG
QIIPWNFPILMAVWKLAPAIAAGNCVVLKPAEQTPASILVVMELIGDLLPPGVINVVNGFGLEAGKPLASNPRIAKIAFT
GETTTGRLIMQYASQNLIPVTLEFGGKSPNIFFGDVVNEDDDFFDKALEGFTMFALNQGEVCTCPSRALVHESIYDRFIE
RAIKRVEAITQGSPLDPATMIGAQASSEQLEKILSYVDIGRQEGAECLTGGARGTREGDLADGFYMQPTVFKGHNKMRIF
QEEIFGPVLSVTTFKDDEEALAIANDTLYGLGAGVWTRDGTRAYRFGRAIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRE
THKMMLDHYQQTKNMLVSYSSKKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-147 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-153 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-152 63
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_002964640.1 aldehyde dehydrogenase VFG0082 Protein 1e-147 64