Gene Information

Name : ureC (MexAM1_META1p3224)
Accession : YP_002964247.1
Strain : Methylobacterium extorquens AM1
Genome accession: NC_012808
Putative virulence/resistance : Virulence
Product : urease alpha subunit
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 3363467 - 3365179 bp
Length : 1713 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1400317, 1624427, 2211515, 7721685, 7855593, 7909161, 8318888, 8808930; Product type e : enzyme

DNA sequence :
ATGTCCGCCCGCCTGCCCCGCGCCGCCTATGCCCCCATGTTCGGGCCGACCACCGGCGATCGTATTCGGCTGGCCGACAC
CAGCCTCGAGATTGAGGTCGAGCGTGATCTCACGACCTACGGCGAGGAGGTGAAGTTCGGCGGCGGCAAGGTGATCCGCG
ACGGGATGGGCCAGTCGCAGGCGACCAACGCCGAGGGCGCCGTCGATACCGTCATCACCAACGCGGTGGTGCTCGACCAT
TGGGGCATCGTGAAATGCGATGTCGGCATCCGCGCCGGTCGGATCTTCAAGCTCGGAAAGGCCGGCAACCCGGACGTTCA
GGCGAATGTCGACATCGTCGTCGGCCCCGGCACCGAGGTGATTGCCGGCGAGGGCAAGATCCTCACGGCCGGCGGCTTCG
ACAGCCACATCCACTTCATCTGCCCGCAGCAGATCGAGGAGGCGCTCTGCTCCGGTGTCACGACGATGCTCGGCGGCGGC
ACCGGGCCGGCGCATGGCACCTTCGCCACCACCTGCACGCCCGGCCCCTGGCACATCGCGCGGATGATCGAGGCGGCGGA
TTCCTTCCCGATGAACCTCGCTTTTGCCGGGAAGGGCAACGCCTCGGTGCCCGGTGCGCTGGAGGAGATGATCCGCGCCG
GCGCCTGCGCGATGAAGCTGCATGAGGACTGGGGCACCACGCCCGCCGCGATCGATACCTGCCTCTCGGTGGCGGATGCC
TTCGACGTGCAGGTCATGATCCACACCGACACGCTCAACGAGTCGGGCTTCGTCGAGGACACGATCGCCGCCTTCAAGGG
CCGCACCATCCACGCCTTCCACACCGAGGGCGCCGGTGGCGGCCATGCGCCGGACATCATGCGGGTCGCCGGCCTCGCGA
ACGTGCTCCCGTCGTCGACGAACCCGACGCGGCCCTTCACGAAGAACACCATCGACGAGCATCTCGACATGCTGATGGTG
TGCCACCACCTCGACCCGTCGATTCCCGAAGACCTCGCCTTCGCCGAGAGCCGCATCCGCAAGGAGACCATCGCGGCCGA
AGACATCCTGCACGACATCGGCGCGCTCTCGATGATGTCGTCCGACAGTCAGGCGATGGGCCGGGTCGGCGAAGTCGTGA
TCCGCACATGGCAGACCGCCGACAAGATGAAGCGCCAGCGCGGCGCCCTGCCCGGAGACGCGTCGGGCAACGACAACCTG
CGCGCCCGGCGCTACGTGGCGAAATACACGATCAACCCGGCCATCGCGCACGGCGTCTCGCGCCATATCGGCTCGATCGA
GCCGGGCAAGCTCGCCGACCTCGTGCTGTGGACGCCCGCCTTCTTCGGGGTGAAGCCGGACCTCGTGCTCAAGGGCGGCA
TGATCGCCACCGCGCCGATGGGCGACCCCAACGCCTCGATCCCCACGCCGCAGCCGGTGCATTACCGGCCGATGTTCGGC
GCCTACGGCCGCGCGCCCTATGCCACCGCGCTCACCTTCGTCTCGCGGGCGGCGCTCGAGGACGGCGTGAAAGAGAAGCT
GCGCGTCTCCAAGGAGCTGGTGGCGGTGGAGAACGTGCGCGGCGGCATCTCGAAGAAGAGCATGATCCTCAACGACGCGA
CCCCGAACATCGAGATCGACCCCGAGACCTACGACGTGCGCGCCGACGGCGAATTGCTGGTCTGCGAGCCGGCGGAGGTC
TTGCCGATGGCGCAGCGCTACTTCCTGTTCTGA

Protein sequence :
MSARLPRAAYAPMFGPTTGDRIRLADTSLEIEVERDLTTYGEEVKFGGGKVIRDGMGQSQATNAEGAVDTVITNAVVLDH
WGIVKCDVGIRAGRIFKLGKAGNPDVQANVDIVVGPGTEVIAGEGKILTAGGFDSHIHFICPQQIEEALCSGVTTMLGGG
TGPAHGTFATTCTPGPWHIARMIEAADSFPMNLAFAGKGNASVPGALEEMIRAGACAMKLHEDWGTTPAAIDTCLSVADA
FDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIMRVAGLANVLPSSTNPTRPFTKNTIDEHLDMLMV
CHHLDPSIPEDLAFAESRIRKETIAAEDILHDIGALSMMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGDASGNDNL
RARRYVAKYTINPAIAHGVSRHIGSIEPGKLADLVLWTPAFFGVKPDLVLKGGMIATAPMGDPNASIPTPQPVHYRPMFG
AYGRAPYATALTFVSRAALEDGVKEKLRVSKELVAVENVRGGISKKSMILNDATPNIEIDPETYDVRADGELLVCEPAEV
LPMAQRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 66
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 66
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-169 63
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 3e-169 63
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-169 63
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-169 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_002964247.1 urease alpha subunit VFG0270 Protein 8e-160 60