Gene Information

Name : lpd (MexAM1_META1p1542)
Accession : YP_002962681.1
Strain : Methylobacterium extorquens AM1
Genome accession: NC_012808
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase, FAD/NAD(P)-binding, component of the 2-oxoglutarate dehydrogenase and the pyruvate dehydrogenase complexes
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 1613585 - 1614988 bp
Length : 1404 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10806385; Product type e : enzyme

DNA sequence :
ATGTCCTACGATCTCATCGTCATCGGCACCGGCCCCGGCGGCTATGTCTGCGCCATCCGCGCGGCCCAGCTCGGGCTGAA
GACCGCGGTGGTCGAGAAGCGGGCGACCCACGGCGGCACCTGCCTCAATGTCGGCTGCATCCCGTCCAAGGCGCTGCTGC
ACGCATCGGAAGCCTTCGAGGAGGCCAACAAGCACTTTTCGGAGTTGGGCATCGACGTGGGCACGCCGAAGCTTGATCTC
AAAAAAATGCAGAGCTTCAAGCAGAGCGGCGTGGACGGCAACACCAAGGGCGTCGAGTTCCTGCTCAAGAAGAACAAGGT
CGATACCTATCACGGCCGCGGCCGCATCGCCGGGGCCGGCCGCGTCGAGGTAATCTCGGACGACGGCGGCAACCAGTTGC
TGGAGACGAAGAACATCGTCATCGCCACCGGCTCCGACGTGACCCGGCTGCCGGGCGTCGAGATCGACGAGAAGACGGTG
GTCTCCTCCACCGGCGCGCTCGAACTCGCCGAGGTGCCCAAGCGCCTCGTGGTGATCGGCGCGGGCGTGATCGGGCTCGA
ACTCGGCTCGGTCTGGCGCCGCCTCGGCGCCGAGGTCACCGTGATCGAGTATCTCGACCGCGTGCTGCCGGGCATGGACG
GCGAGGTCGGCAAGCAGTTCCAGCGCATCCTGGCCAAGCAGGGCATGGTCTTCAAGCTCTCGACCAAGGTGACCGGTGTC
GAGACCGGCAAGAAGGGCCGCGCCACCGTCACCGTCGAGCCGGCGCAGGGCGGCGAGCCGGAGAAGCTCGAGGCCGACGT
GGTGCTCGTGGCCATCGGCCGGGTGCCCTACACGGAAGGGCTCGGGCTCGAGACGGTGGGCGTGGCGACCGACGACAAGG
GCCGGATCGAGGTCGATTCGCACTACGCCACCAACGTCACCGGCATCTACGCCATCGGCGACGTGATCGCCGGGCCGATG
CTCGCCCACAAGGCGGAGGACGAGGGCGTCGCGGTCGCCGAGATCCTGGCCGGCCAGTCGGGCCACGTGAATTACGGCGT
GATCCCGAACGTCGTCTACACCTTCCCCGAGGTCGCCTCGGTCGGCAAGACCGAGGAGGAGCTGAAGAAGGACGGGATCG
CCTACAACGTCGGCAAGTTCCCCTTCACCGCCAACGGCCGGGCCAAGGCCAACGGCACCACCGACGGCTTCGTGAAGATC
CTCGCGGACGCGCAGACCGACCGGGTGCTCGGCGTGCACATCGTCGGGGCGGATGCCGGCAACCTCATCGCCGAGGTCGC
GGTGGCGATGGAGTTCGCAGCCTCCGCCGAGGACATCGCCCGCACCTGCCACGCCCACCCGACGCTGACCGAGGCGATCA
AGGAAGCCGCCCTCGCCGTCGACAAGCGCGCGATCCACGTCTGA

Protein sequence :
MSYDLIVIGTGPGGYVCAIRAAQLGLKTAVVEKRATHGGTCLNVGCIPSKALLHASEAFEEANKHFSELGIDVGTPKLDL
KKMQSFKQSGVDGNTKGVEFLLKKNKVDTYHGRGRIAGAGRVEVISDDGGNQLLETKNIVIATGSDVTRLPGVEIDEKTV
VSSTGALELAEVPKRLVVIGAGVIGLELGSVWRRLGAEVTVIEYLDRVLPGMDGEVGKQFQRILAKQGMVFKLSTKVTGV
ETGKKGRATVTVEPAQGGEPEKLEADVVLVAIGRVPYTEGLGLETVGVATDDKGRIEVDSHYATNVTGIYAIGDVIAGPM
LAHKAEDEGVAVAEILAGQSGHVNYGVIPNVVYTFPEVASVGKTEEELKKDGIAYNVGKFPFTANGRAKANGTTDGFVKI
LADAQTDRVLGVHIVGADAGNLIAEVAVAMEFAASAEDIARTCHAHPTLTEAIKEAALAVDKRAIHV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 5e-69 42