Gene Information

Name : ureC (MexAM1_META1p1073)
Accession : YP_002962239.1
Strain : Methylobacterium extorquens AM1
Genome accession: NC_012808
Putative virulence/resistance : Virulence
Product : urease alpha subunit
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : -
Position : 1119209 - 1120927 bp
Length : 1719 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type e : enzyme

DNA sequence :
ATGAGCAAAATCTCGCGGCGGCAATACTCGGATCTCTACGGGCCGACGACAGGCGACAAGATCAGGCTCGCCGATACGGA
CCTCTACATCGAGATCGAGAAGGACCTTCGGGTTTACGGCGAAGAGGCCGTCTATGGCGGCGGCAAGACGCTTCGGGATG
GCATGGGTTACGACAACGAGTTGACCAGTGCGGCGGGCGCACCGGATCTCGTCATCACCAATGTCACGATCCTCGACGCG
GTCCAGGGCGTCATCAAGGCCGATCTCGGCATCAAGAACGGCCTGATCGTCGGAATCGGGAAGGCCGGCAATCCCTCGAC
GATGTCGGGGGTGACACGGGGGCTCGCGCTCGGACCGGGCACGGACGCCATTTCCGGCGAGCACCTCATCCTGACCGCGG
GCGGCATCGACGCCCACGTCCACTTCATCTCGCCGCAGCAGGCCCAGGCCGCGCTCAGCAACGGTGTGACGACGCTGTTC
GGCGGCGGCATCGGCCCGTCCGACGGCACCAACGGCACGACCATCACGCCGGGCACGTGGAACATCGAGATGATGCTCCG
CTCCTTCGATGCCTGGCCGGTCAATGCGGGCGTGCATGGCAAGGGCAATTGCTCGGCGCTTCTCCCGATCGAGGAGCAGA
TCCGGGCCGGCGCGATGGGTTTGAAGGTTCACGAAGATTGGGGCAGCACCCCGGCGGCGATCCGCATGGCCCTGACCGCC
GCGGACGATCACGACGTCCAAGTCTGCATCCACACGGACACCTTGAACGAGGCGGGTTTCGTCGAGAGCACCATCGCCGC
GTTCGAGGGGCGCACGATCCACACCTACCACACGGAGGGCGCGGGCGGCGGCCACGCACCGGACATCATCCGGGTGGCGG
GCATCTCCAACGTCATCCCCAGTTCGACCAATCCGACCATGCCCTACGGCATCAATTCGCAGGCGGAATTGTTCGACATG
GTGATGGTCTGTCACAACCTCAGCCCGAAGATCCCGACGGACGTCGCCTTCGCGGAAAGCCGCGTCCGCGCCGAGACCAT
CGCGGCGGAAAACGTCCTGCACGATCTCGGTGCGATCTCGATCCTGTCGAGCGATAGCCAGGCCATGGGCCGCGTCGGCG
AGAACTGGGCGCGCACCATTCAGACGGCCCATCTGATGAAGGCGCGGCTCGGTGCCTATCCGGGGGATGCCTCCGGCAAC
GACAATCAGCGCGTGCTGCGCTTCGTCGCCAAGGTGACGATCAATCCCGCCATCGTGGCGGGGGTCTCGCACGTGATCGG
ATCGGTCGAGGTCGGCAAGATGGCGGACCTCGTCCTCTGGGAGCCGGCCTTCTTCGGCGCGAAGCCGAAGATGGTCATCA
AGGGCGGCATGATCTCCTGGGCGATCATGGGAGACCCCAACGCCTCGCTGCCGACACCGCAGCCGGTCGTCTATCGTCCG
ATGTTCGGCGCTCTCGGCCCGGCCGTGGCCAAGACACGCGTGACCTTCACGTCTCATGCCGCCTACGAGGACGGGATCGT
GGATCGTTACGAGCTGACGTCCAAGGTCGTGCCCGTCTACGGCACGCGCACCATCACCAAGGCGTCGATGGTTCGAAACG
ACCGGCTTCCGGTCATCAAGGTCAACCCGGAAACCTTTGCGGTGATGGTCGACGGCAAGCACGCCACGATCGAGCCCGCC
ACGCATCTTCCGCTCGCGCAGCTCCATTTCTTCAGCTGA

Protein sequence :
MSKISRRQYSDLYGPTTGDKIRLADTDLYIEIEKDLRVYGEEAVYGGGKTLRDGMGYDNELTSAAGAPDLVITNVTILDA
VQGVIKADLGIKNGLIVGIGKAGNPSTMSGVTRGLALGPGTDAISGEHLILTAGGIDAHVHFISPQQAQAALSNGVTTLF
GGGIGPSDGTNGTTITPGTWNIEMMLRSFDAWPVNAGVHGKGNCSALLPIEEQIRAGAMGLKVHEDWGSTPAAIRMALTA
ADDHDVQVCIHTDTLNEAGFVESTIAAFEGRTIHTYHTEGAGGGHAPDIIRVAGISNVIPSSTNPTMPYGINSQAELFDM
VMVCHNLSPKIPTDVAFAESRVRAETIAAENVLHDLGAISILSSDSQAMGRVGENWARTIQTAHLMKARLGAYPGDASGN
DNQRVLRFVAKVTINPAIVAGVSHVIGSVEVGKMADLVLWEPAFFGAKPKMVIKGGMISWAIMGDPNASLPTPQPVVYRP
MFGALGPAVAKTRVTFTSHAAYEDGIVDRYELTSKVVPVYGTRTITKASMVRNDRLPVIKVNPETFAVMVDGKHATIEPA
THLPLAQLHFFS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 2e-149 58
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 2e-149 58
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-141 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-141 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-141 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-141 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC YP_002962239.1 urease alpha subunit VFG0270 Protein 3e-141 58