Gene Information

Name : Mlut_21440 (Mlut_21440)
Accession : YP_002958166.1
Strain : Micrococcus luteus NCTC 2665
Genome accession: NC_012803
Putative virulence/resistance : Virulence
Product : NAD-dependent aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 2296322 - 2297845 bp
Length : 1524 bp
Strand : -
Note : PFAM: Aldehyde dehydrogenase family

DNA sequence :
ATGACCGTCTACGCATTCCCGGGCACCGAGGGAGCCAAGGTCGAGTTCAAGTCCCGCTACGAGCACTTCATCGGCGGAGA
GTGGACACCCCCGGTCAAGGGCCAGTACTTCGAGAACGTCACGCCCGTGACGGGCAAGGTGTTCTGCGAGGTCGCCCGCG
GCACGGCCGAGGACATCGACGCCGCCCTCGACGCCGCCTGGAAGGCCGCCCCGGCCTGGGGCGCCACCTCGCCGGCCGAG
CGGGCGCTCGTGCTGCACCGCATCGCGGACCGCATGGAGGAGAACCTCGAGATGCTGGCGGTCGCGGAGACGTGGGACAA
CGGCAAGGCCGTCCGGGAGACCCTCAACGCGGACGTCCCGCTGGCCATCGACCACTTCCGGTACTTCGCCGGCGCGATCC
GAGCGCAGGAGGGCCGCCTGTCCCAGCTGGATGAGGACACCGTCGCCTACCACTTCCACGAGCCGCTCGGCGTGGTCGGC
CAGATCATCCCGTGGAACTTCCCGCTGCTGATGGGGGTGTGGAAGCTGGCGCCCGCGCTGGCCGCGGGCAACGCCGTCGT
GATCAAGCCCGCGGAGCAGACCCCGGCCTCGATCATGGTGTTCATCGAGCTGATCGCGGACCTGTTGCCGGCCGGCGTCG
TCAACGTGGTCAACGGCTTCGGCCTCGAGGCCGGCAAGCCGCTCGCGCAGTCGCCGCGCATCCGCAAGATCGCGTTCACG
GGCGAGACGACGACGGGCCGGCTGATCATGCAGTACGCCTCGGAGAACATCATCCCGGTGACCCTGGAGCTGGGCGGCAA
GTCGCCCAACGTCTTCTTCGAGGACGTCATGGCGGCCGACGACGCCTACTGGGACAAGGCGCAGGAGGGCTTCACCCTGT
TCGCGCTGAACCAGGGCGAGGTCTGCACGTGCCCGTCGCGTGCGCTCGTGCAGGAGTCGATCGCGGAGAAGTTCCTCGAC
GCCGTCGTGGAGCGGACCTCGCGCATCGTCACCGGCAACCCCCTCGACACGGACGTGATGATGGGCGCCCAGGTCTCCAA
CGACCAGCTCGAGAAGATCATGTCCTACCTGGACATCGGCCGTCAGGAGGGCGCCGAGGTGCTGATCGGCGGCGCCCGCG
CCGAGATGGAGGGGGAGCTGGCCGGCGGCTACTACGTGCAGCCCACGATCTTCCGTGGGGACAACTCGATGCGCATCTTC
CAGGAGGAGATCTTCGGGCCGGTGGTCTCGACGACCACGTTCACCGACTTCGACGACGCCATGCGGATCGCCAACGACAC
GCTCTACGGGCTCGGCGCCGGCGTGTGGTCCCGGAACGGCAACACCGCCTACCGCGCGGGCCGGGCGATCCAGGCCGGCC
GCGTGTGGGTGAACAACTACCACGCCTACCCGGCCCACGCCGCGTTCGGTGGGTACAAGTCCTCCGGCATCGGCCGTGAG
AACCACCTGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTCGTCTCCTACTCCGAGGACAAGCTCGGGTTCTT
CTGA

Protein sequence :
MTVYAFPGTEGAKVEFKSRYEHFIGGEWTPPVKGQYFENVTPVTGKVFCEVARGTAEDIDAALDAAWKAAPAWGATSPAE
RALVLHRIADRMEENLEMLAVAETWDNGKAVRETLNADVPLAIDHFRYFAGAIRAQEGRLSQLDEDTVAYHFHEPLGVVG
QIIPWNFPLLMGVWKLAPALAAGNAVVIKPAEQTPASIMVFIELIADLLPAGVVNVVNGFGLEAGKPLAQSPRIRKIAFT
GETTTGRLIMQYASENIIPVTLELGGKSPNVFFEDVMAADDAYWDKAQEGFTLFALNQGEVCTCPSRALVQESIAEKFLD
AVVERTSRIVTGNPLDTDVMMGAQVSNDQLEKIMSYLDIGRQEGAEVLIGGARAEMEGELAGGYYVQPTIFRGDNSMRIF
QEEIFGPVVSTTTFTDFDDAMRIANDTLYGLGAGVWSRNGNTAYRAGRAIQAGRVWVNNYHAYPAHAAFGGYKSSGIGRE
NHLMMLDHYQQTKNLLVSYSEDKLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-139 61
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-148 60
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-148 60
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-148 60
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-147 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mlut_21440 YP_002958166.1 NAD-dependent aldehyde dehydrogenase VFG0082 Protein 2e-139 61