Gene Information

Name : leuS (Mlut_12480)
Accession : YP_002957307.1
Strain : Micrococcus luteus NCTC 2665
Genome accession: NC_012803
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 1348429 - 1350936 bp
Length : 2508 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGAGCCAGACCACCGACAGCGCCGTGCCGGCCACCCCCAGCATCCCCGCCGACGCGGAGTACTCGTTCCGTGACGTGGA
GGCCCGCTGGGCCGGGTACTGGGAGCAGGCCGGGACGTTCGCCCCGCGCGAGGACGGCTCCGAGACCCGCACCGTGGTCG
ACATGTTCCCGTACCCGTCGGGCGACCTGCACATGGGGCACGCCGAGGCGTTCGCGATGGGCGACGTCGTCGCGCGCCAC
TGGATGCAGCGCGGCTTCGACGTGCTGCACCCCATCGGCTGGGACTCCTTCGGCCTGCCGGCCGAGAACGCCGCCATCAA
GCGCGACGCCCACCCGGCCGAGTGGACCTACGCGAACATCGAGACGCAGAAGCGCTCCTTCCAGCGGTACGGCATCGCCG
TGGACTGGTCCCGTGAGCTGCACACCTCGGACCCCGAGTACTACCGGTGGACCCAGTGGCTGTTCCAGCAGCTGTACCGC
AAGGGCCTGGCGTACCGGAAGGACTCCCCGGTCAACTGGTGCCCCCAGGACCAGACGGTGCTCGCCAACGAGCAGGTCGT
GGACGGCCGCTGCGAGCGCTGCGGCACCGAGGTCACCAAGCGGACCCTGAACCAGTGGTACTTCCGCATCACCGAATACG
CGGACGCGCTGCTGGACGACATGGACCAGCTCACCGGCCACTGGCCCGAGCGCGTGCTCGCCATGCAGCGCAACTGGATC
GGCCGCTCCGAGGGCGCCCACGTCGACTTCCAGGTCGAGGACGGCCCCGTCGTCACGGTCTTCACCACGCGGCCGGACAC
GCTGTACGGCGCGACCTTCATGGTGGTCGCCGCCGACGCGCCGCTGGCCGCCGAGCTCGCCGGCGACGACGTGCGGGCCG
AACTCGAGGCGTACCGCGAGGACCTGAAGAAGGTCTCGGACATCGACCGCCAGGCCACGGACCGCCCGAAGAGCGGCGTG
TTCCTGGGCCGCCACGCCGTGAACCCGCTGACCGGTGAACGCCTGCCGATCTGGGCCTCGGACTACGTGCTGGCCGACTA
CGGCACGGGCGCCATCATGGCCGTGCCGGCCCACGACCAGCGCGACCTCGACTTCGCCCGCGCCATGGGCCTGCCCGTGC
GCACCGTGCTGGACACCGGTGAGGAGGACCCGGCGGTCTCCGGCGTCGCGACGACCGGCGAGGGCATCCTGGTGAACTCC
GGCGAGCTCGACGGCCTGGACAAGACCGCGGCCATCGCGCGGGCCATCGAGATCATGGAGGAGCGCGGCACCGGCCGGGC
CACCACCACGTACCGCCTGCGCGACTGGCTGCTCTCCCGTCAGCGCTTCTGGGGCACCCCGATCCCCGTGGTGCACTGCC
CGGACTGCGGCGAGGTCCTCGTGCCGGAGGACCAGCTGCCGGTCACCCTGCCGACCGACCTGAAGGGCGAGCAGCTGGCC
CCGAAGGGCCGGTCACCCCTGGCCGCGGCGACGTCGTGGGTCGAGGTGGACTGCCCGCAGTGCGGCGGCCCCGCGCGACG
GGACACCGACACCATGGACACGTTCGTGGACTCGTCCTGGTACGTGCTCCGCTACGCGTCCCCGAACGACGACGCCCGCG
TCTTCGACCCCGAGGCCCTGCGCCGCTGGCTGCCCGTGGACCAGTACGTGGGCGGCGTGGAGCACGCGATCCTGCACCTG
CTGTACGCCCGCTTCTTCACCAAGGCCCTGCACGACCTCGGCCTGGTGCCCTTCACCGAGCCGTTCCGCTCCCTGCTCAA
CCAGGGCCAGGTGCTCAACGGCGGCAAGGCCATGTCCAAGTCGCTGGGCAACGGCGTGGACCTGGGCGATCAGCTGGACG
AGTTCGGCGTCGACGCCGTGCGTCTGACCATGGTGTTCGCCTCGCCGCCTGAGGACGACGTGGACTGGGCCGACGTCGCC
CCGGGCGCGGCCGGCAAGTTCCTGGCCCGCGCGTGGCGCCTGGCCCGCGACGTCCGCGCGACGGGCGCCCCGGCCGGCGC
GGACCCGGCGGACGGGGCCGTGGCCCTGCGCCGGGTGACGCACCGGACCGTGCACGAGGCCCAGCAGCTGCTGGACGACG
GCAAGTTCAACGTGGTCGTCGCCAAGACGATGGAGCTGGTCAACGCGGCCCGCAAGGAGATCGACGCGGGTGCCGGCGCG
GCCGATCCCGCCGTCCGCGAGGCCGTCGAGGCCGTGGCCGTGCTGCTCTCCCTCGTGGCGCCGTACACGGCCGAGGACAT
GTGGGTCCTCCTGGGCCACGAGCCGTCCGTGGTCCGCGCCGGCTGGCCCGCGGTGGACGAGTCGCTGCTGGTCGAGGACA
CCGTCACGGCCGTCGTCCAGGTCAAGGGCAAGGTCCGCGACACCCTCGAGGTGCCTGCGGACATCACGGCCGAGGACCTC
GAGGCGCGCGCCCGCGCGTCGCAGAAGGTGCGGAACTTCATCGGGGACGCCCAGATCGTCAAGGTGATCGTGCGCGAGCC
CAAGCTCGTGAACCTGGTGATTCGCTGA

Protein sequence :
MSQTTDSAVPATPSIPADAEYSFRDVEARWAGYWEQAGTFAPREDGSETRTVVDMFPYPSGDLHMGHAEAFAMGDVVARH
WMQRGFDVLHPIGWDSFGLPAENAAIKRDAHPAEWTYANIETQKRSFQRYGIAVDWSRELHTSDPEYYRWTQWLFQQLYR
KGLAYRKDSPVNWCPQDQTVLANEQVVDGRCERCGTEVTKRTLNQWYFRITEYADALLDDMDQLTGHWPERVLAMQRNWI
GRSEGAHVDFQVEDGPVVTVFTTRPDTLYGATFMVVAADAPLAAELAGDDVRAELEAYREDLKKVSDIDRQATDRPKSGV
FLGRHAVNPLTGERLPIWASDYVLADYGTGAIMAVPAHDQRDLDFARAMGLPVRTVLDTGEEDPAVSGVATTGEGILVNS
GELDGLDKTAAIARAIEIMEERGTGRATTTYRLRDWLLSRQRFWGTPIPVVHCPDCGEVLVPEDQLPVTLPTDLKGEQLA
PKGRSPLAAATSWVEVDCPQCGGPARRDTDTMDTFVDSSWYVLRYASPNDDARVFDPEALRRWLPVDQYVGGVEHAILHL
LYARFFTKALHDLGLVPFTEPFRSLLNQGQVLNGGKAMSKSLGNGVDLGDQLDEFGVDAVRLTMVFASPPEDDVDWADVA
PGAAGKFLARAWRLARDVRATGAPAGADPADGAVALRRVTHRTVHEAQQLLDDGKFNVVVAKTMELVNAARKEIDAGAGA
ADPAVREAVEAVAVLLSLVAPYTAEDMWVLLGHEPSVVRAGWPAVDESLLVEDTVTAVVQVKGKVRDTLEVPADITAEDL
EARARASQKVRNFIGDAQIVKVIVREPKLVNLVIR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-147 42