Gene Information

Name : Mlut_11020 (Mlut_11020)
Accession : YP_002957163.1
Strain : Micrococcus luteus NCTC 2665
Genome accession: NC_012803
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1181098 - 1182585 bp
Length : 1488 bp
Strand : +
Note : PFAM: Pyruvate kinase, alpha/beta domain; Pyruvate kinase, barrel domain; TIGRFAM: pyruvate kinase

DNA sequence :
ATGCGACACGCGAAGATCATCGCCACCTTTGGGCCCGCCACCGACTCCGACGAGACCACCCGCGCCATCATCCGCGCGGG
GGCGGACGTCGTCCGCCTCAACATGAGCCACGGCGACCACGCGGTGCATGAGACGTCCTACGAGCGGGTGCGTCGGCTGA
GCGTGGAGGAGCGGCGCCCGGTCGCGATCTTCGCGGACCTCCAGGGCCCCAAGATCCGCCTCGGCCGCTTCACCGACGGC
CCGCATCTGCTCGAGAGGGGCGATCGGATCACCATCACCACCCGGGACGTGCCCGGGACCCGCGAGCTGGTCGGCACCAC
CCACAAGGGGCTGCCCGGGGACGTCGCCCCCGGTGACGTGCTCCTGGTGGACGACGGCAAGGTGCGCCTGCGCGCCGTCG
AGGTCACGGACACGGACGTGCTGGCCGAGGTCGAGGTGCCGGGCATGGTCTCGGACAACAAGGGGATCAACCTGCCCGGC
GTGGCGGTGAACGTGCCGGCCCTGTCCGAGAAGGACGAGCGGGACCTGCGCTGGGCGCTGCGCACCGGCGTGGACATGGT
GGCGCTGTCCTTCGTGCGGGACGCCGCGGACGTGGACCGGGTGCACGAGATCATGGACGAGGAGGAGCGCCGGGTCCCGG
TCATCGCCAAGATCGAGAAGCCCCAGGCGGTGGAGAACCTCGAGGCCATCGTGGACGCGTTCGACGCCATCATGGTGGCC
CGCGGCGACCTCGGCGTGGAGCTGCCGCTCGAGGACGTGCCCGTGGTGCAGAAGCGCGCAGTGGACCTCGCCCGCCGCTG
GGCGAAGCCGGTCATCGTGGCCACGCAGGTGCTCGAGTCGATGATCGACAGCCCGCGCCCGACGCGCGCCGAGGCCTCGG
ACTGCGCCAACGCCGTGCTCGACGGCGCGGACGCCGTCATGCTCTCGGGCGAGACCTCGGTGGGCGCATATCCGGTCGAG
ACGGTCCAGACGATGGCCCGGATCATCGAGTCCACCGAGACCCACGGCCTGGAGCTCATCCACCCGCTCGGCTCGCGTCC
CCGCACGCGCGGCGGCGCGATCACCCGGGCCGCCGTCGAGGTCGCGAACCAGCTCGAGATCCCGTTCCTCGCCACGTTCA
CCGAGTCCGGCGACTCGGCCCGTCGGCTCAGCCGCCTGCGGCCGCGTCAGCCGATCTACGCGTTCACCCACCACGAGCAC
ACGCACAACATCCTGTGCCTGACCTGGGGCGTCTACCCGAAGATGGTCCCGTTCCAGGACTCCACGGACAAGATGACCCT
CCAGGTGGAGCAGTCGCTCACATCGGAGGGCATCGCCCAGCACGGCGACCTCGTGGTCATCGCCGCCGGGTCCCCTCCCG
GGGCCGTGGGCTCCACGAACACGCTGCGCGTGCACCGCGTGGGCGACGACGCCGCGGGCGGCTCGTCCGCCGCCTCGCCG
CAGACGCGCGAGCCGGTCGGCTTCTGGCCGGCCCGCTCCCCGCTCTGA

Protein sequence :
MRHAKIIATFGPATDSDETTRAIIRAGADVVRLNMSHGDHAVHETSYERVRRLSVEERRPVAIFADLQGPKIRLGRFTDG
PHLLERGDRITITTRDVPGTRELVGTTHKGLPGDVAPGDVLLVDDGKVRLRAVEVTDTDVLAEVEVPGMVSDNKGINLPG
VAVNVPALSEKDERDLRWALRTGVDMVALSFVRDAADVDRVHEIMDEEERRVPVIAKIEKPQAVENLEAIVDAFDAIMVA
RGDLGVELPLEDVPVVQKRAVDLARRWAKPVIVATQVLESMIDSPRPTRAEASDCANAVLDGADAVMLSGETSVGAYPVE
TVQTMARIIESTETHGLELIHPLGSRPRTRGGAITRAAVEVANQLEIPFLATFTESGDSARRLSRLRPRQPIYAFTHHEH
THNILCLTWGVYPKMVPFQDSTDKMTLQVEQSLTSEGIAQHGDLVVIAAGSPPGAVGSTNTLRVHRVGDDAAGGSSAASP
QTREPVGFWPARSPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 9e-65 41
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-64 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-65 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-65 41
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 1e-56 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Mlut_11020 YP_002957163.1 pyruvate kinase VFG0479 Protein 2e-65 41