Gene Information

Name : guaA (DMR_22390)
Accession : YP_002953616.1
Strain : Desulfovibrio magneticus RS-1
Genome accession: NC_012796
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2513984 - 2515534 bp
Length : 1551 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCCAGCCCGACAAGGTTCTCATCCTCGACTTCGGCTCCCAGTACACCCAGCTCATTGCCCGCCGCGTGCGCGAGGC
CGGGGTGTATTCCGAAATCCATCCCTGCACCGTCACGGCCAAGGAAGTGGCGGCCATGGCCCCCAAGGCCGTGATCCTGT
CCGGCGGCCCTTCCAGCGTCGCCGACGCCGACGCGCCGCCCTTTGATCCGGCCGTGTTCGATCTGGGCCTGCCCATGCTG
TGCATCTGCTACGGCATGCAGCTGTTGGCCCACCACCTGCCCGGCGGCCAGGTGGCCGCCTCCACCGACCGCGAGTATGG
TCGGGCCGATTTGCAGCTTTTGGCCGACACGCCCCTTTTCGCCGGCCTGCCGCAAAAAGACGGGCACATCGTCTGGATGT
CCCACGGCGACAAGGTCATGGCCGCGCCGGACGGCTTTGTGGTGGCCGCGCGCACCAAAAACGTGGACATCGCCGCCCTG
GCCAACGCTTCCCGTCGCATCTACGCCCTGCAGTTCCACCCCGAGGTGGCCCACACCGAGGACGGCGAGCGCATTCTCCA
CAACTTCCTGTTCGAGATCGCCGGCCTGACCTCGGGCTGGACCATGTCGAGCTTCCTGGAAACCGAGCTGGCCTCGCTCA
AGGAAAAAGTCGGCGACGACGAAGTGGTCTGCGCCCTGTCCGGCGGCGTCGATTCCACGGTAGTGGCCGTCATGCTCCAC
AAGGCCATCGGCAAGAAGCTTCACTGCATCTTTGTCGACAATGGTCTTTTGCGCATGGGCGAGGGCGAGGAAGTGGCCGC
CTATCTGCGCGAACACTTTGACCTCAATCTGCATTACGTTGACGCCGCCAAACTCTTTCTCGACAAGCTGGCCGGCGTGA
CCGACCCCGAGGAAAAGCGCAAGATCATCGGCAAGACCTTCATCGAGGTCTTCGAGGTCGAAGCGGCCAAGTTGCCCAAG
GTCAAGTACCTGGCCCAGGGCACGCTGTATCCCGACGTCATCGAGTCCGTATCCTTCAAGGGACCCTCGGCGGTCATCAA
GAGCCACCACAACGTGGGCGGGCTGCCCGAGGTCATGAAGCTGGCGCTTATTGAACCCCTGCGTGAACTGTTCAAGGACG
AGGTGCGCAAGGTGGCGGTGGAGCTCGGCATGCCCGACTTCATCATCTGGCGTCATCCCTTCCCCGGACCGGGGCTGGCC
ATCCGCATCATCGGCGAGGTGACCGAGGAACGGCTTGAGATTTTGCGGCGAACGGATAAGATCGTCCAGAGCGAGCTTGT
CGCCTCGGGCTGGTACCGCAAGGTCTGGCAGGGGTTTGCCGTGCTGCTGCCGCTCAAGACCGTCGGGGTCATGGGCGACG
GCCGTACCTATGAAAACGTGGCCGCCATCCGCGTGGTGGACAGTCTCGACGCCATGACCGCCGACTGGAGCCGTCTCCCG
TCGGAAATCCTGGCCGTTATGTCCAACCGCATCATCAATGAGGTCAAAGGCGTCAACCGCGTGGTGTTCGACGTCTCGTC
CAAGCCGCCCGCGACCATCGAGTGGGAATAG

Protein sequence :
MSQPDKVLILDFGSQYTQLIARRVREAGVYSEIHPCTVTAKEVAAMAPKAVILSGGPSSVADADAPPFDPAVFDLGLPML
CICYGMQLLAHHLPGGQVAASTDREYGRADLQLLADTPLFAGLPQKDGHIVWMSHGDKVMAAPDGFVVAARTKNVDIAAL
ANASRRIYALQFHPEVAHTEDGERILHNFLFEIAGLTSGWTMSSFLETELASLKEKVGDDEVVCALSGGVDSTVVAVMLH
KAIGKKLHCIFVDNGLLRMGEGEEVAAYLREHFDLNLHYVDAAKLFLDKLAGVTDPEEKRKIIGKTFIEVFEVEAAKLPK
VKYLAQGTLYPDVIESVSFKGPSAVIKSHHNVGGLPEVMKLALIEPLRELFKDEVRKVAVELGMPDFIIWRHPFPGPGLA
IRIIGEVTEERLEILRRTDKIVQSELVASGWYRKVWQGFAVLLPLKTVGVMGDGRTYENVAAIRVVDSLDAMTADWSRLP
SEILAVMSNRIINEVKGVNRVVFDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-132 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 7e-133 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-133 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-119 53