Gene Information

Name : GWCH70_0886 (GWCH70_0886)
Accession : YP_002949022.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 948259 - 949680 bp
Length : 1422 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: bcl:ABC0047 aldehyde dehydrogenase

DNA sequence :
ATGTACATAAACGGCGAATGGGTAGACTCCGTTTCTGGTAAAACGTTTGAAACAGTCAATCCTGCAACTGGTGAAAAGTT
AGCGGATGTAGCAGAAGCAGGTCCGGAGGATATTGATTTGGCAGTAAGAGCGGCAAGAGAAGCGTTTGATCGTGGACCAT
GGTCAAGAATAAGCGCAGCTGAGAGAAGCCGCTTAATTTATAAACTGGCTGATTTAATGGAAGAGCATAAATTAGAATTA
GCACAGCTTGAAACATTGGACAACGGGAAACCAATTCGCGAAACATCTAATGCAGACGTACCTTTAGCGATTGAACATCT
CCGTTATTATGCAGGCTGGGCAACGAAAATTGTGGGGCAAACCATCCCTGTTCAAGGAAACTATTTTAACTATACGCGTC
ATGAACCAGTGGGGGTAGTCGGACAAATTATTCCGTGGAACTTCCCATTATTAATGGCTGCATGGAAACTAGGCGCTGCC
CTTGCGACAGGTTGTACAGTTGTCTTAAAGCCTGCTGAGCAAACACCTCTATCTGCTCTTTACTTAGCAAAATTAATAGA
AGAAGTTGGATTTCCGAAAGGTGTTGTCAACATTGTACCTGGCTATGGCGAAACAGCGGGTGCGCCACTAGTGGATCATC
CATTAGTGAATAAAATCGCCTTCACAGGTTCAACGGCTGTCGGAAAACAAATCATGAAGCAAGCAAGCGAGTCATTAAAA
CGGGTAACACTTGAACTTGGCGGTAAATCCCCGAACATCATTTTGCCTGATGCAGATTTGACGAAGGCAGTTCCTGGCGC
ATTTATGGGAATTATGTTTAACCAAGGTCAAGTATGCTGCGCAGGAAGCCGCTTATATGTTCAAAAGAAAATGTACGACA
ATGTAGTAGCTGATTTAGCCTCTCTTACAAAAACAATTAAACAAGGCAATGGTTTATTGCCAGAGACGACAATGGGCCCT
CTGGTTTCAGAAGAACAGCAAAAACGCGTCAAAGGATATATTGATAAAGGAATTGAAGAAGGAGCTGAATTAGTAGTAGG
CGGTACTATCCCGTACGAACAAGGTTATTTCGTCGCTCCAACAGTTTTTGCTGATGTGAACCATTCAATGACCATCGCAA
AAGAAGAAATTTTCGGCCCAGTTGTAGCGGCGATGCCGTTTGATGATTTAGATGATCTTGTTGCAAAGGCAAACGATTCA
CTTTATGGTTTAGCTGCTGGTGTTTGGACGCAGGATATAAAGAAAGCCCACTACCTCGCACATCGCATTAAAGCGGGTAC
GGTATGGGTGAACTGCTATAACGTATTTGACGCGGCAAGTCCATTTGGAGGCTATAAGCAATCAGGCATCGGACGTGAAT
GTGGCAGCTACGCGTTAGATAACTATACAGAAGTGAAGAGTGTCTGGGTAAACATGAACTAA

Protein sequence :
MYINGEWVDSVSGKTFETVNPATGEKLADVAEAGPEDIDLAVRAAREAFDRGPWSRISAAERSRLIYKLADLMEEHKLEL
AQLETLDNGKPIRETSNADVPLAIEHLRYYAGWATKIVGQTIPVQGNYFNYTRHEPVGVVGQIIPWNFPLLMAAWKLGAA
LATGCTVVLKPAEQTPLSALYLAKLIEEVGFPKGVVNIVPGYGETAGAPLVDHPLVNKIAFTGSTAVGKQIMKQASESLK
RVTLELGGKSPNIILPDADLTKAVPGAFMGIMFNQGQVCCAGSRLYVQKKMYDNVVADLASLTKTIKQGNGLLPETTMGP
LVSEEQQKRVKGYIDKGIEEGAELVVGGTIPYEQGYFVAPTVFADVNHSMTIAKEEIFGPVVAAMPFDDLDDLVAKANDS
LYGLAAGVWTQDIKKAHYLAHRIKAGTVWVNCYNVFDAASPFGGYKQSGIGRECGSYALDNYTEVKSVWVNMN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-94 47
aldA ACK75577.1 aldehyde dehydrogenase Not tested VPI Protein 8e-65 47
aldA ACK75580.1 aldehyde dehydrogenase Not tested VPI Protein 1e-63 47
aldA ACK75588.1 aldehyde dehydrogenase Not tested VPI Protein 8e-64 47
aldA ACK75585.1 aldehyde dehydrogenase Not tested VPI Protein 2e-64 47
aldA ACK75593.1 aldehyde dehydrogenase Not tested VPI Protein 2e-64 47
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 4e-98 47
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 4e-98 47
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 4e-98 47
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-91 47
aldA ACK75582.1 aldehyde dehydrogenase Not tested VPI Protein 1e-64 47
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-97 47
aldA ACK75574.1 aldehyde dehydrogenase Not tested VPI Protein 1e-64 46
aldA ACK75590.1 aldehyde dehydrogenase Not tested VPI Protein 1e-64 46
aldA ACK75596.1 aldehyde dehydrogenase Not tested VPI Protein 1e-64 46
hpaE AAO17179.1 HpaE Not tested tcd island Protein 1e-84 45
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 5e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GWCH70_0886 YP_002949022.1 aldehyde dehydrogenase VFG0082 Protein 5e-95 47