Gene Information

Name : GWCH70_0374 (GWCH70_0374)
Accession : YP_002948563.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 428536 - 430257 bp
Length : 1722 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGCAAAACATCAAATCTTTCATGCAATTTCCTGCGAGTAAAAAGGTGTATGTCGAAGGTTCAAGACCGGATATTCGTGT
TCCGATGAGAGAAATTACGTTAAGTCCAACAAAGACAGAAACAGGAATCATCGAAAATGAACCTGTTCGTGTTTATGACA
CAAGCGGTCCTTACACCGATCCTGATTTTCAGCCGGACATTCAAAAAGGATTGCCGCCGCTAAGAAAACGCTGGATTTTA
GAAAGGGGCGACGTTGAAGAATACGAGGGGCGTCCAGTGAAACCGGAAGATAACGGATTCCGTAATGGGAAGCAATCAGA
GATTACTCTGCCTTTCGAGAGAAAACCGCTGCGCGCAAAAAAAGGAAAAACTGTGACGCAAATGCATTACGCAAAACGAG
GGATTATTACGCCGGAGATGGAATTTGTTGCGATTCGCGAAAATATAGATCCGGAAATCGTGCGTCAAGAAGTTGCCGCA
GGCAGAGCGATTATTCCTTCGAATATTAACCATCCGGAAAGTGAACCGATGATTATTGGGAGTCGTTTTCATGTAAAAAT
TAACGCGAATATTGGCAATTCCGCAGTCACATCATCCATTGAAGAAGAAGTCGAAAAAATGCTTTGGGCGGTGCGCTGGG
GAGCAGACACGATTATGGACTTATCGACGGGAAAACACATTCATGCGACACGAGAATATATTATTCGCAATTCCCCTGTA
CCTGTCGGGACGGTTCCGATTTATCAAGCGCTTGAAAAAGTGAACGGCGTCGTCGAAGACTTAACGTGGGAAATTTACCG
TGATACGCTCATCGAACAAGCGGAACAAGGGGTGGACTATTTTACGATTCACGCGGGGGTGCTGCTTCGTTACATACCGA
TGACCGTAAACCGAACGACTGGCATTGTTTCACGCGGCGGCTCGATTATGGCGCAATGGTGTTTAGCCCACCATGAAGAA
AACTTCTTATACACGCATTTTGAAGAAATATGCGAGATTTTGAAAACGTACGATATTGCAGTATCGCTTGGAGACGGGCT
GCGCCCAGGCTCGATTGCCGATGCGAATGACGAAGCGCAGTTTGCTGAATTGGAGACGCTCGGAGAATTAACAGAAATCG
CTTGGAAGCATGATGTGCAAGTGATGATTGAAGGACCAGGGCATGTGCCGATGCATAAAATTAAGGAAAATGTCGATAAG
CAAATCGAAATTTGCAAAGGTGCGCCGTTTTACACATTAGGACCGCTTACGACCGATATCGCGCCGGGATATGACCACAT
TACATCCGCGATCGGAGCAGCGATCATTGGCGCGTACGGAACGGCGATGCTTTGTTACGTGACGCCAAAAGAGCATTTAG
GGTTGCCGAATAAAGATGATGTGCGCGAAGGAGTGATCGCTTATAAAATCGCAGCACACGCGGCCGATTTAGCCAAAGGG
CACCCGGGAGCGCAACGGCGGGATGACGCGTTATCAAAAGCGCGCTTTGAGTTTCGTTGGAACGATCAGTTCAACCTTTC
GCTTGATCCAGATCGAGCTCGGGAATATCATGATGAAACATTGCCGGCGGAAGGGGCGAAAGTCGCGCACTTTTGTTCGA
TGTGCGGGCCGAAGTTTTGCTCGATGAAAATTTCACATGAGCTGCAAAAAACGGTGAGGGAAGAAGGGATGAAACAAAAA
GCGAAGGAGTTTGTCGAAAATGGCTCATCTCTCTATCGATGA

Protein sequence :
MQNIKSFMQFPASKKVYVEGSRPDIRVPMREITLSPTKTETGIIENEPVRVYDTSGPYTDPDFQPDIQKGLPPLRKRWIL
ERGDVEEYEGRPVKPEDNGFRNGKQSEITLPFERKPLRAKKGKTVTQMHYAKRGIITPEMEFVAIRENIDPEIVRQEVAA
GRAIIPSNINHPESEPMIIGSRFHVKINANIGNSAVTSSIEEEVEKMLWAVRWGADTIMDLSTGKHIHATREYIIRNSPV
PVGTVPIYQALEKVNGVVEDLTWEIYRDTLIEQAEQGVDYFTIHAGVLLRYIPMTVNRTTGIVSRGGSIMAQWCLAHHEE
NFLYTHFEEICEILKTYDIAVSLGDGLRPGSIADANDEAQFAELETLGELTEIAWKHDVQVMIEGPGHVPMHKIKENVDK
QIEICKGAPFYTLGPLTTDIAPGYDHITSAIGAAIIGAYGTAMLCYVTPKEHLGLPNKDDVREGVIAYKIAAHAADLAKG
HPGAQRRDDALSKARFEFRWNDQFNLSLDPDRAREYHDETLPAEGAKVAHFCSMCGPKFCSMKISHELQKTVREEGMKQK
AKEFVENGSSLYR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 71
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 71
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 66