Gene Information

Name : GWCH70_3259 (GWCH70_3259)
Accession : YP_002951168.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 3285340 - 3286620 bp
Length : 1281 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase ; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: esi:Ex

DNA sequence :
ATGAATAGAAAAATTGCAGTAGTTGGATTAGGGTACGTAGGATTACCTGTTGCAGTAGCGTTTGGTAAAAAAGGACGTAT
TATCGGTTTTGATATTAATGAGCATCGAATCAATACGTTGAAACAAGGTATTGATTATACAAAAGAAGTCGAATCTCAAG
ATTTATTAGAAGCAGATATTGATTTTACCAATGATCCGTCTCGACTCCGTGAGGCGGATTTTATCATTGTGGCGGTTCCA
ACGCCGATTACTGAAACGAAACAGCCAGATTTAACGCCATTAATTAAAGCGTCTGAAACCGTTGGTTCGAATTTGCAAAA
AGGCGCGATTGTCGTGTACGAATCGACGGTATATCCGGGGGCTACGGAGGAAGTATGCGTGCCTGTGCTTGAGAAAGCAT
CAGGTTTAAAAGCGGGTGTTGATTTCTTTGTGGGATATTCCCCAGAACGAATTAATCCAGGGGATAAAGAACATACATTC
ACCAAAATTACAAAGGTAGTATCTGGACAAAATGATGAAGTATTAGAAATAATCGCGGGGGTTTACGGTTCGGTAGTAGA
AGCTGGTGTGTATCGAGCAAGTTCTATAAAAGTGGCAGAAGCAGCCAAAGTTATTGAAAATACGCAACGAGATTTAAATA
TTGCGTTAATGAATGAGTTGGCGATTATTTTTGATAAACTTGGAATTGATACGGCAGAGGTGCTAGAGGCTGCGGGAACG
AAATGGAACTTCCTACCGTTTACGCCAGGGTTAGTCGGAGGACACTGCATTGGTGTTGATCCTTATTACCTAACGCATAA
AGCGGAAAGTGTTGGGTATCATCCAGAGGTTATTTTAGCAGGGCGTCGTATTAACGATAACATGGGTAAATTTATCGCTA
CCTCATTAGTAAAACAAATGATTCATCAAAATATGCCGATTCAAGGCGCGAGAGTTACTGTACTAGGTTTAACATTTAAA
GAAAACGTACCAGATCTTCGCAACTCGAAAGTAATCGATGTGATTCGTGAATTGCAAGAGTTCGGTGTTGAGGTGCAAGT
GACAGACGCCCTTGCCGATAAGGATGAAGCAGTGCGTGAATATGGTATTGAATTAGTGGATTATGATAAGTTAATTCCAG
CTGATGCGGTGGTATTAGCTGTTCCACATGATGAGTATGTGGAAAAAGGATGGGAACAGTTCGATAGACTATTAAAACAT
GGTAAGGGCATTGTTGTGGATATTAAAAGTAAATTAGAAAAAGAAACTTGTCCAAAACAAATAAAACTTTGGCGATTATA
G

Protein sequence :
MNRKIAVVGLGYVGLPVAVAFGKKGRIIGFDINEHRINTLKQGIDYTKEVESQDLLEADIDFTNDPSRLREADFIIVAVP
TPITETKQPDLTPLIKASETVGSNLQKGAIVVYESTVYPGATEEVCVPVLEKASGLKAGVDFFVGYSPERINPGDKEHTF
TKITKVVSGQNDEVLEIIAGVYGSVVEAGVYRASSIKVAEAAKVIENTQRDLNIALMNELAIIFDKLGIDTAEVLEAAGT
KWNFLPFTPGLVGGHCIGVDPYYLTHKAESVGYHPEVILAGRRINDNMGKFIATSLVKQMIHQNMPIQGARVTVLGLTFK
ENVPDLRNSKVIDVIRELQEFGVEVQVTDALADKDEAVREYGIELVDYDKLIPADAVVLAVPHDEYVEKGWEQFDRLLKH
GKGIVVDIKSKLEKETCPKQIKLWRL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 7e-131 66
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-111 57
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-111 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GWCH70_3259 YP_002951168.1 nucleotide sugar dehydrogenase VFG0431 Protein 5e-112 57