Gene Information

Name : GWCH70_3145 (GWCH70_3145)
Accession : YP_002951070.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 3173089 - 3174609 bp
Length : 1521 bp
Strand : +
Note : PFAM: aldehyde dehydrogenase; KEGG: gka:GK3198 NAD-dependent aldehyde dehydrogenase

DNA sequence : 
ATGATTTACGCTCAACCTGGGCAGCCTGGTTCACTCATCACGTTCAAAAAACGTTATGAAAACTTCATTGGCGGCAAATG
GGTCCCTCCTGTCGACGGGGAGTATTTTGAAAATATTTCTCCAGTCACTGGAAAACCTTATTGTGAAGTGCCGCGCTCCA
AAGCAGCGGATATCGAGCTAGCATTGGACGCTGCTCATGCTGCAAAAGATGCATGGGGCCGTACTTCCCCTGCTGAACGC
GCGCGAATCCTCAACAAAATTGCTGACCGTATGGAAGAAAACTTGGAAATGCTTGCTGTTGCAGAAACATGGGAAAACGG
CAAGCCGATTCGCGAAACGTTGAATGCCGACATTCCGCTTGCGATCGACCATTTCCGCTATTTCGCCGGCTGCATCCGTG
CGGAAGAAGGCACTTTATCCGAAATCGATCACGATACGGTCGCCTATCACTTTAAAGAGCCTCTTGGTGTTGTCGGACAA
ATCATCCCTTGGAACTTCCCGCTTTTAATGGCAGCATGGAAACTCGCTCCAGCGTTAGCAGCTGGAAACTGCGTTGTCTT
AAAACCTGCAGAGCAAACACCGACATCGATCCTTGTTTTAATGGAGTTAATTCAAGACATCCTTCCTCCAGGTGTTGTCA
ACGTTGTGAACGGATTCGGCGTAGAAGCTGGAAAACCGCTTGCTTCAAGCAGCCGCATCGCTAAAATTGCTTTCACTGGC
GAAACGACAACAGGACGTCTAATCATGCAATACGCATCGCAAAACATTATTCCAGTCACATTGGAACTTGGAGGAAAATC
GCCAAACATCTTCTTCGAAGACGTGGCGGCAAAAGATGATGAATTTTTCGATAAAGCGATCGAAGGCTTTACGTTGTTTG
CTTTAAACCAAGGCGAAATATGTACATGCCCTTCCCGCGCTCTCATTCATGAATCCATTTACGACAAATTTATGGAGCGC
GCGTTAGAGCGTGTAAAACAAATTAAACAAGGCAATCCGCTCGATACGGAAACGATGATCGGCGCACAAGCATCTTCGGA
ACAATTAGAAAAAATATTATCGTACATTGATATCGGCAAACAGGAAGGCGCCGAATTGCTTGCCGGCGGAGAACGGAATA
TCCTAGAAGGCGACTTAAAAGACGGATATTACGTAAAACCGACCGTCTTTAAAGGCCACAATAAAATGCGCATTTTCCAA
GAAGAAATTTTCGGACCAGTCGTTGCAGTCACTACATTTAAAGACATGGACGAAGCATTAGAGATCGCCAATGACACATT
GTATGGCTTAGGTGCAGGCGTATGGACGCGCGACATTAATACCGCTTATCGCGTTGGCCGCGGCATTCAAGCAGGACGCG
TCTGGACAAACTGCTACCACATGTATCCTGCACACGCAGCATTCGGAGGCTATAAGCAATCCGGATTCGGCCGCGAAACA
CATAAAATGATGCTTGAACATTATCAACAAACGAAAAACTTGCTTGTCAGCTATTCACCGAAAAAACTAGGACTCTTCTA
A

Protein sequence : 
MIYAQPGQPGSLITFKKRYENFIGGKWVPPVDGEYFENISPVTGKPYCEVPRSKAADIELALDAAHAAKDAWGRTSPAER
ARILNKIADRMEENLEMLAVAETWENGKPIRETLNADIPLAIDHFRYFAGCIRAEEGTLSEIDHDTVAYHFKEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPTSILVLMELIQDILPPGVVNVVNGFGVEAGKPLASSSRIAKIAFTG
ETTTGRLIMQYASQNIIPVTLELGGKSPNIFFEDVAAKDDEFFDKAIEGFTLFALNQGEICTCPSRALIHESIYDKFMER
ALERVKQIKQGNPLDTETMIGAQASSEQLEKILSYIDIGKQEGAELLAGGERNILEGDLKDGYYVKPTVFKGHNKMRIFQ
EEIFGPVVAVTTFKDMDEALEIANDTLYGLGAGVWTRDINTAYRVGRGIQAGRVWTNCYHMYPAHAAFGGYKQSGFGRET
HKMMLEHYQQTKNLLVSYSPKKLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-137 67
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-145 66
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-145 66
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-145 66
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-145 66
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-58 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GWCH70_3145 YP_002951070.1 aldehyde dehydrogenase VFG0082 Protein 2e-137 67