Gene Information

Name : GWCH70_3008 (GWCH70_3008)
Accession : YP_002950945.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 3026907 - 3029420 bp
Length : 2514 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGCTTGGAGTATTAAAAAAGGTGTTTGACCCAAACAAACGCCAACTAAGCCGTTTAGAAAAGATTGCTGACCAAGTCGA
TGCGCTTGGCCCAGAGATGGCAAAGCTTTCGGATGAACAGTTGCGTCAAAAGACCGAGGAATTCAAGGCGCGCTATCAAC
AAGGCGAGTCGCTGGATGACTTGTTAGTGGAGGCTTTTGCCGTTGTGCGCGAAGGTGCAAAGCGCGTCCTTGGATTATAT
CCATATAAAGTGCAAATTATGGGCGGTATTGTCCTCCATGAGGGAAATATCGCCGAAATGAAAACAGGGGAAGGGAAAAC
GTTAACGGCAACGATGCCCGTTTATTTAAACGCTTTAACCGGAAAAGGCGTGCATGTCGTGACGGTCAACGAATATTTGG
CGACCCGCGACGCAACGGAAATGGGCAAATTGTATGAGTTTTTAGGATTAACCATCGGTTTGAATTTAAGCGGTATGTCG
CGGGAGGAAAAACAAGCGGCGTATAATGCCGATATTACGTACGGAACAAACAACGAGTTTGGCTTTGACTATTTGCGCGA
TAACATGGTGCTTTATAAAGAACATATCGTACAGCGTCCGCTTCATTATGCGATTATTGACGAAGTGGACTCGATTTTAA
TTGACGAGGCGCGGACGCCGCTCATTATTTCGGGCACCGCGCAAAAATCGACAGCGCTGTATATTCAGGCAAATGCGTTT
GTGCGTACATTGAAAAAAGATGTCGATTATACGTATGATGAGAAAACGAAAAGCGTACAGCTCACCGAAGAAGGGATCAC
GAAAGCGGAAAAAGCGTTTGGAATCGACAACCTATTCGACTTAAAGCATGTAACGCTAAACCATCATATTAACTTGGCGC
TAAGAGCGCATGTGACGATGCATCGGGATGTCGATTATGTGGTGGAAGACGGAAAAGTCGTCATCGTCGACCAGTTTACA
GGCCGCCTAATGCGCGGACGCCGTTATAGTGACGGATTGCATCAAGCGATCGAAGCAAAAGAAGGATTGGAAATTCAAAA
TGAGTCGATGACGCTTGCGACGATTACGTTCCAAAATTACTTCCGCATGTATGAAAAGCTTGCGGGAATGACGGGAACGG
CGAAAACGGAAGAAGAAGAATTCCGAAACATTTATAACATGCAAGTCGTTGTCATCCCGACAAACAAACCGGTCATCCGT
GAAGACCGTCCAGATTTAATTTTCCGGACGATGGAAGGAAAATTCCGCGCCGTAGTAGAAGATATCGCACAGCGCCATGC
GAAAGGGCAGCCGGTGCTTGTCGGGACGGTGTCGATTGAAACATCGGAACTTCTTTCAAACATGTTGAAAAAACGCGGGA
TTCCGCATAATGTATTAAATGCGAAAAACCATGCGAAAGAAGCGGAAATTATCGCCCAAGCCGGTCAAAAAGGCGCTGTA
ACGATCGCGACAAACATGGCCGGACGCGGTACGGATATTAAGCTTGGCGAAGGTGTCAAAGAGCTTGGCGGATTAGCGGT
CATTGGCACGGAGCGCCATGAAAGCCGCCGTATTGATAACCAGTTGCGCGGTCGTGCGGGACGCCAAGGCGACCCAGGTG
TATCGCAATTTTATCTATCGCTTGAAGATGAGTTGATGCGCCGCTTCGGTTCGGAAAGTTTAATGTCGATGATGGACCGT
TTAGGCATGGATGATTCGCAGCCAATTCAAAGCAAAATGGTCACTAAAGCGGTCGAATCGGCGCAAAAACGGGTAGAAGG
CAACAACTTTGATGCGCGTAAACAGCTGCTTCAATACGATGATGTGTTGCGTGAGCAGCGTGAAATTATTTATCGCCAGC
GCTATGAAGTGCTTGACTCCGACAACTTGCGCGGCATTATCGAAAAAATGATTCAATCGGTCATTGAGCGGGTCGTCAAC
GCTCATACGCCGAAAGAAGAGCTTCCGGAAGAATGGAATTTAAAAGGAATCATCGATTACGTCAATGCCAACCTGTTGCC
GGAAGGCGATGTGACCGTTAACGATTTGCGCGGCAAAGAGCCGGAAGAAATGATTGAGCTCATTTGGGAAAAAGTGAAAG
CGCGCTATGATGAAAAAGAACAGCAAATTCCGCCGGAACAAATGCGCGAATTTGAACGCGTCATCGTCCTTCGCGCCGTC
GATATGAAGTGGATGGACCATATCGACGCGATGGAGCAGCTGCGTCAAGGAATTCATTTGCGCGCGTACGGACAAATTGA
TCCGCTTCGCGAATATCAAATGGAAGGATATGCGATGTTTGAAAACATGATCGCTTCCATTGAAGAAGAAGTAGCAAAAT
ATATTATGAAAGCGGAAATCCACAGCAATCTCGAACGCCAGGAAGTGGCAAAAGGCGAAGCGGTTCATCCGAAAGAAGGA
GAAGGCGAAGTAAAACGGAAGCCGTACCGCAAGGCCGTTCGCATTGGTCGTAACGACCCTTGCATTTGCGGAAGCGGCAA
AAAGTATAAACATTGCTGCGGAAAAAATGCATAA

Protein sequence :
MLGVLKKVFDPNKRQLSRLEKIADQVDALGPEMAKLSDEQLRQKTEEFKARYQQGESLDDLLVEAFAVVREGAKRVLGLY
PYKVQIMGGIVLHEGNIAEMKTGEGKTLTATMPVYLNALTGKGVHVVTVNEYLATRDATEMGKLYEFLGLTIGLNLSGMS
REEKQAAYNADITYGTNNEFGFDYLRDNMVLYKEHIVQRPLHYAIIDEVDSILIDEARTPLIISGTAQKSTALYIQANAF
VRTLKKDVDYTYDEKTKSVQLTEEGITKAEKAFGIDNLFDLKHVTLNHHINLALRAHVTMHRDVDYVVEDGKVVIVDQFT
GRLMRGRRYSDGLHQAIEAKEGLEIQNESMTLATITFQNYFRMYEKLAGMTGTAKTEEEEFRNIYNMQVVVIPTNKPVIR
EDRPDLIFRTMEGKFRAVVEDIAQRHAKGQPVLVGTVSIETSELLSNMLKKRGIPHNVLNAKNHAKEAEIIAQAGQKGAV
TIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDNQLRGRAGRQGDPGVSQFYLSLEDELMRRFGSESLMSMMDR
LGMDDSQPIQSKMVTKAVESAQKRVEGNNFDARKQLLQYDDVLREQREIIYRQRYEVLDSDNLRGIIEKMIQSVIERVVN
AHTPKEELPEEWNLKGIIDYVNANLLPEGDVTVNDLRGKEPEEMIELIWEKVKARYDEKEQQIPPEQMREFERVIVLRAV
DMKWMDHIDAMEQLRQGIHLRAYGQIDPLREYQMEGYAMFENMIASIEEEVAKYIMKAEIHSNLERQEVAKGEAVHPKEG
EGEVKRKPYRKAVRIGRNDPCICGSGKKYKHCCGKNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-139 43