Gene Information

Name : guaA (GWCH70_0237)
Accession : YP_002948433.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 263343 - 264881 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGAACAAAAACAGGAAATGATTATTGTTCTAGATTTTGGGAGCCAGTATAACCAATTAATTACTCGCCGCATTCGCGA
GTTTGGGGTATACAGCGAATTGCATCCACATACGATTACAGCGGAAAAAATTCAAGAAATGAATGTAAAAGGAATCATTT
TTTCTGGCGGTCCAAACAGCGTATATGATGATAATGCGTTTACGTGTGATCCGAAAATTTTTGAGCTTGGTTTGCCGATT
TTAGGAATTTGTTATGGCATGCAGTTAATGACCCATCATTTGGGTGGAAAAGTAGAAAAAGCAACACATCGTGAGTACGG
AAAAGCAATGATTCAAGTAAGGAATGCTTCCGCCCTTTTTGAACGTCTCCCAGACGAGCAAGTGGTCTGGATGAGCCACG
GCGATTTAGTCACTGCTCCGCCAGAAGGGTTTACTGTAGATGCTGTTAGCGCTTCTTGTCCAATTGCGGCAATGAGCAAT
GAGGCGAAAAAATTTTATGCGGTGCAATTCCATCCAGAAGTGCGCCATTCCGTTTACGGAAACGATATTTTAAGAAATTT
CGTATTTGACGTGTGCCAATGTAAAGGCGATTGGACAATGGAAAGCTTTATCGATAGCGAAGTGCGCAAAATTCGCGAGC
TTGTTGGAGATAAAAAAGTGCTTTGCGCGTTAAGCGGCGGTGTCGATTCTTCCGTGGCGGCTGTGCTTGTGCATCGCGCC
ATCGGCGATCAACTCACATGTATTTTTGTCGATCACGGGCTCCTTCGCAAAGGAGAAGCAGAAAGCGTGATGAAAACATT
CCGCGAAGGATTCCATATGAACGTTATTAAAGTGGACGCAAAAGAGCGCTTTTTATCAAAATTAAAAGGGGTAACCGATC
CGGAACAAAAACGCAAAATCATCGGCAACGAATTTATTTATGTGTTTGATGATGAAGCGGCAAAATTAGAAGGAATAGAG
TTTTTAGTACAAGGGACGCTTTATACGGATATTATTGAAAGCGGCACGGCGACAGCACAGACGATTAAGTCTCATCATAA
TGTCGGCGGTCTGCCGGAAGATATGAAATTCAAACTCATCGAGCCGCTTAACACGTTATTTAAAGATGAAGTGCGCGCAC
TCGGAACGGAATTGGGCCTTCCAGACGAAATTGTTTGGCGGCAGCCGTTCCCAGGACCAGGATTAGGCATTCGCGTGCTT
GGCGAAGTAACAGAGGAAAAGTTGGAAATCGTTCGTGAATCGGACGCGATTTTACGGGAGGAAATTAAAAAAGCGGGACT
TGATCGGGAAATTTGGCAATATTTCACGGTGCTTCCGGACATTCGCAGCGTCGGTGTGATGGGTGATGCCCGCACATATG
ACTATACGGTCGGCATTCGCGCTGTTACATCGGTGGATGGCATGACAGCGGATTGGGCGCGCATTCCTTGGGAAGTGCTT
GAGAAAATTTCCACGCGTATCGTTAATGAAGTGCCGCATGTCAATCGAGTTGTATACGATATTACAAGTAAGCCGCCGGC
AACAATCGAATGGGAATGA

Protein sequence :
MEQKQEMIIVLDFGSQYNQLITRRIREFGVYSELHPHTITAEKIQEMNVKGIIFSGGPNSVYDDNAFTCDPKIFELGLPI
LGICYGMQLMTHHLGGKVEKATHREYGKAMIQVRNASALFERLPDEQVVWMSHGDLVTAPPEGFTVDAVSASCPIAAMSN
EAKKFYAVQFHPEVRHSVYGNDILRNFVFDVCQCKGDWTMESFIDSEVRKIRELVGDKKVLCALSGGVDSSVAAVLVHRA
IGDQLTCIFVDHGLLRKGEAESVMKTFREGFHMNVIKVDAKERFLSKLKGVTDPEQKRKIIGNEFIYVFDDEAAKLEGIE
FLVQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMKFKLIEPLNTLFKDEVRALGTELGLPDEIVWRQPFPGPGLGIRVL
GEVTEEKLEIVRESDAILREEIKKAGLDREIWQYFTVLPDIRSVGVMGDARTYDYTVGIRAVTSVDGMTADWARIPWEVL
EKISTRIVNEVPHVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-138 55