Gene Information

Name : hemC (GWCH70_2580)
Accession : YP_002950541.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2609805 - 2610740 bp
Length : 936 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGAAAAATCATCGTTGGATCGCGCCGCAGCAAACTTGCGCTCACCCAGACGAACTGGGTCATCGAGCGGCTTCGGCA
ATTAGGAGCGCCGTTTGAATTTGAAGTAAAAGAAATTGTCACCAAAGGGGACAAAATTATTGATGTAACGTTATCCAAAG
TCGGTGGCAAAGGATTGTTCGTAAAAGAAATTGAACATGCAATGCTAAACGGCGAAATTGATATGGCAGTACATAGCATG
AAAGATATGCCCGCTGTTTTGCCTGATGGTCTTATCATTGGCTGCGTGCCGCCGCGTGAGGATCATCATGATGTGTTGAT
TAGTAAAAACAAAGAAACGTTTGCGAATCTTCCAAGTGGAGCGATCGTTGGGACAAGCAGTTTGCGCCGTTCTGCACAAA
TACTGGCAAAACGGCCGGATTTAAAGATCAAATGGATTCGCGGCAATATCGATACGAGACTTGCGAAGCTGCAAAACGAA
GATTACGATGCCATTATTCTTGCGGCGGCCGGATTAGTGCGCATGGGTTGGGCAAGAGATGTCATTACGGAATATTTATC
AACAGATGTATGTCTTCCTGCTGTTGGACAAGGAGCACTGGCGGTGGAATGCCGCGAAAATGATGAAGAATTGCGGGAAT
GGCTGCAAAAATTAAACGATGTTCACACCGAGCGGGCTGTTTTGGCCGAACGTGTATTTTTACAACAAATGGAAGGCGGC
TGTCAAGTGCCGATTGCGGGATATGCATATATTGACGATCGCGAGGATATCGTTTTAACCGCTCTTGTTGCTTCTCCAGA
CGGAAAAGAGATATATAAAGAAACGGTAAGCGGATCGAATCCGGAAGAAGTCGGAACGAACGCTGCGAAAATGTTAATAG
AGCGTGGTGCGAAAGCATTAATTGATCGTATTAAAGAGGAGATGAATCGACAGTGA

Protein sequence :
MRKIIVGSRRSKLALTQTNWVIERLRQLGAPFEFEVKEIVTKGDKIIDVTLSKVGGKGLFVKEIEHAMLNGEIDMAVHSM
KDMPAVLPDGLIIGCVPPREDHHDVLISKNKETFANLPSGAIVGTSSLRRSAQILAKRPDLKIKWIRGNIDTRLAKLQNE
DYDAIILAAAGLVRMGWARDVITEYLSTDVCLPAVGQGALAVECRENDEELREWLQKLNDVHTERAVLAERVFLQQMEGG
CQVPIAGYAYIDDREDIVLTALVASPDGKEIYKETVSGSNPEEVGTNAAKMLIERGAKALIDRIKEEMNRQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 3e-60 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 3e-60 49