Gene Information

Name : GWCH70_2474 (GWCH70_2474)
Accession : YP_002950435.1
Strain : Geobacillus sp. WCH70
Genome accession: NC_012793
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 2501251 - 2502387 bp
Length : 1137 bp
Strand : -
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
GTGAGACGAAAAACAAAACTAATTCACGGCGGCATCTCAGGTGATCCGCATACAGGAGCGGTTTCGGTTCCGATTTATCA
AGTTAGCACGTATAAACAAGAAGGAATTGGCGGTCATAAAGGCTTTGAATATTCGCGTACTGGCAACCCGACTCGCCACG
CATTGGAAGAACTTATTAAAGATTTAGAAGAAGGTTATGCCGGATTTGCGTTCAGCTCTGGAATGGCGGCGATTACGGCG
GTCATGATGCTGTTTAACAGCGGGGATCACGTCATTTTAACGGACGATGTGTATGGCGGCACATATCGCGTCATGACGAA
AGTGCTAAACCGCCTGGGGCTTGAATCGACTTTTATTGATACAAGCGACCTTTCAAACATCGAAAAACATATTCAGCCGA
ACACAAAAGCGCTTTACATTGAAACGCCAACCAATCCACTCTTAAAAATTACGGACATTCAAGCTGCTTCTGCCATCGCC
AAAAAGCATGGCTTGCTTACGATCGTCGACAACACGTTCAGCACCCCGTATTGGCAAACGCCGATTGCCCTTGGCGCCGA
CATTGTTGTCCATAGCGCAACGAAATATTTAGGCGGCCATAGCGATGTGGTCGCTGGTTTAGCGGTGGTCAATTCGGAAG
AGTTAGCAGAAAAACTACATTTTATTCAAAACTCTACCGGAGGAATTCTCGGTCCGCAAGATTCATGGCTTTTAATGCGC
GGCATCAAGACGCTTGGTGTACGCATGGAGGAGCATGAAGAAAACACGAGGAAAATCGTTGAATTTTTAGTGAACCATCC
AGCGGTCCAAAAAGTGTATTATCCAGGATTGGAAACACATCCAAACTATGAAATTGCCAAAAAACAAATGCGCGGATTTG
GCGGCATGGTCTCCTTTGATGTCGGAAGCGCGGAGAAAGCCGATCGAGTGTTAAACCGTGTGCGCTACTTTACGCTCGCG
GAAAGCTTGGGAGCAGTCGAAAGCTTAATTTCGTTGCCGGCGAAAATGACGCACGCATCCATTCCGAAAGAACGTCGTGA
ACAATTAGGCATTACTGATGGGTTGATCCGCATTTCCGTTGGATTGGAAGATGTGGAAGATTTACTTGAAGATTTAGCAC
AGGCATTGCATGGTTAA

Protein sequence :
MRRKTKLIHGGISGDPHTGAVSVPIYQVSTYKQEGIGGHKGFEYSRTGNPTRHALEELIKDLEEGYAGFAFSSGMAAITA
VMMLFNSGDHVILTDDVYGGTYRVMTKVLNRLGLESTFIDTSDLSNIEKHIQPNTKALYIETPTNPLLKITDIQAASAIA
KKHGLLTIVDNTFSTPYWQTPIALGADIVVHSATKYLGGHSDVVAGLAVVNSEELAEKLHFIQNSTGGILGPQDSWLLMR
GIKTLGVRMEEHEENTRKIVEFLVNHPAVQKVYYPGLETHPNYEIAKKQMRGFGGMVSFDVGSAEKADRVLNRVRYFTLA
ESLGAVESLISLPAKMTHASIPKERREQLGITDGLIRISVGLEDVEDLLEDLAQALHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-106 60
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-105 60
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-75 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GWCH70_2474 YP_002950435.1 cystathionine beta-lyase BAC0207 Protein 7e-68 42