Gene Information

Name : Vapar_6035 (Vapar_6035)
Accession : YP_002947869.1
Strain :
Genome accession: NC_012792
Putative virulence/resistance : Resistance
Product : Gentamicin 3'-N-acetyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : 2.3.1.60
Position : 760748 - 761239 bp
Length : 492 bp
Strand : +
Note : PFAM: GCN5-related N-acetyltransferase; KEGG: tgr:Tgr7_1824 gentamicin 3'-N-acetyltransferase

DNA sequence :
ATGTCCACGACCCCCGCCAGCTACGAGGTTCGGCAGCTCTCGGCCGACGACGGTCCGCTGATGACCGAGCTTCTCGCGGT
TTTCGGCAAAGCCTTCGACGAACCGGCCGCCTACGCCGCCAGCCGCCCTCGGCCTGCGTACCTGCGGCAGTTGCTGGGCA
GCGACTATTTCATCGCGCTGGCGGCGCGCGAGGGGTCGCAGGTCATCGGCGGCCTCGCGGCCTACGAGCTGAAAAAGTTC
GAGCAGGAACGCAGCGAGATCTACATCTACGACCTGGCCGTTGCCGCCGGGCACAGGCGCCGGGGCGTGGCGACCGCGTT
GATCCGCGAGCTCCAGCGCATCGGCGCCGAACGCGGGGCCTATGTGATCTTCGTGCAGGCCGATCCGCCCGATGCGCCGG
CCGTCGCGCTGTACACGAAGCTGGGCGTGCGCGAAGACGTGCTGCATTTCGACATTCCGGTGCCGCCGGTGCAACCCGTG
CAGGCGTCCTGA

Protein sequence :
MSTTPASYEVRQLSADDGPLMTELLAVFGKAFDEPAAYAASRPRPAYLRQLLGSDYFIALAAREGSQVIGGLAAYELKKF
EQERSEIYIYDLAVAAGHRRRGVATALIRELQRIGAERGAYVIFVQADPPDAPAVALYTKLGVREDVLHFDIPVPPVQPV
QAS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
acc(3)Ic ACY75521.1 Aac(3) Ic Not tested Tn6060 Protein 1e-26 59
aacCA5 AAR21853.1 aminoglycoside (3) acetyltransferase; AacCA5 or AAC(3)-Ie Not tested SGI1 Protein 3e-25 58
aacCA5 AGF35061.1 aminoglycoside acetyltransferase Not tested SGI1 Protein 3e-25 58
aacCA5 AGK06931.1 aminoglycoside acetyltransferase Not tested SGI1 Protein 3e-25 58
aacCA5 AGK06968.1 aminoglycoside acetyltransferase Not tested SGI1 Protein 3e-25 58
aacCA5 AGK07014.1 aminoglycoside acetyltransferase Not tested SGI1 Protein 3e-25 58
aacCA5 AGK07072.1 aminoglycoside acetyltransferase Not tested SGI1 Protein 3e-25 58
aacC1/aacCA1 ACV89836.1 type A aminoglycoside-(3)-acetyltransferase AacC1 or AacC-A1 or AAC-(3)-Ia Not tested AbaR7 Protein 1e-20 57
aacC1 AFV53117.1 aminoglycoside (3) acetyltransferase AacC1 or AacC-A1 or AAC(3)-Ia Not tested AbGRI2-1 Protein 1e-20 57
aacCA1 AGK36643.1 aminoglycoside-(3)-acetyltransferase AacC1 or AacC-A1 or AAC-(3)-Ia Not tested AbaR26 Protein 1e-20 57
aacC1/aacCA1 ACN81021.1 aminoglycoside-(3)-acetyltransferase AacC1 or AacC-A1 or AAC-(3)-Ia Not tested AbaR5 Protein 1e-20 57
aacC1 YP_005797146.1 aminoglycoside N(3')-acetyltransferase I Not tested AbaR4e Protein 1e-20 57
aacC1/aacCA1 ACN81020.1 aminoglycoside-(3)-acetyltransferase AacC-A1 or AacC1 or AAC-(3)-Ia Not tested AbaR5 Protein 1e-20 57
aac3 CAJ77083.1 Aminoglycoside 3-acetyltransferase Not tested AbaR1 Protein 8e-21 57
aacC1/aacCA1 ACV89833.1 type A aminoglycoside-(3)-acetyltransferase AacC-A1 or AacC1 or AAC-(3)-Ia Not tested AbaR7 Protein 8e-21 57
aacC1 AFV53118.1 aminoglycoside (3) acetyltransferase AacC1 or AacC-A1 or AAC(3)-Ia Not tested AbGRI2-1 Protein 8e-21 57

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Vapar_6035 YP_002947869.1 Gentamicin 3'-N-acetyltransferase AF318077.1.gene3.p01 Protein 4e-21 59
Vapar_6035 YP_002947869.1 Gentamicin 3'-N-acetyltransferase U04610.gene.p01 Protein 7e-21 57
Vapar_6035 YP_002947869.1 Gentamicin 3'-N-acetyltransferase NC_010410.6002585.p0 Protein 4e-21 57
Vapar_6035 YP_002947869.1 Gentamicin 3'-N-acetyltransferase NC_011586.7045205.p0 Protein 4e-21 57