Gene Information

Name : Vapar_3562 (Vapar_3562)
Accession : YP_002945445.1
Strain :
Genome accession: NC_012791
Putative virulence/resistance : Resistance
Product : heavy metal translocating P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 3759388 - 3761676 bp
Length : 2289 bp
Strand : -
Note : TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; cadmium-translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehal

DNA sequence :
ATGGGATTCATGACGAACCAGAATGCCCTGAAACCGATGGCGCCGCATGCCCACTCCCATGCGCCGGCCGCTCCCGAAAC
GGCCTGCTGCGGCAGCACGGCCTGCGGCTCGCCGGCCGTTGCCGTGGCCGCTGCCGACATTCCGAAGGGCGCCTTGCTCT
TTCGCATTCCCACGATGGACTGCGCGGTCGAAGAGTCCGAGATCCGGCGCGCGCTCGAGCCGGTCGCGGGTGTGCGGGGG
CTGCGCTTTCGGCTCGGTGAACGCACCATGGCCATCACGGCCGACGAAGGCGCCTTGCCCGGTGCGCTCGACGCCATCCG
CAAGGCGGGCTTCAAGCCCGAACCGCTGAACGGCGCGGCAGGCAGCCCGGCCGATGGTGCGCAGCCGGTGGCAGCCTCTG
CAGGCATCGCGGGCATGAGCAGCGGCCTCGTGCGCCTCGTTGCCGCGCTGGTGCTCGCCATCGCGGCCGAGGCCGTTGCC
TTTCTCGCACCGGAGGGCGCCGGGTCCATGGCGGCGGAGATGGGGCTCGCGCTCGCGGCCATCGCACTGGCCGGCCTCGA
CACTTACAAGAAGGGCTTTGCCGCGCTGCTGCGCGGGCGCCTGAACATCAACGCGCTGATGGCCGTGGCGGTCACGGGCG
CCTTCCTGATCGGGCAATGGCCCGAGGCCGCGATGGTGATGGCGCTCTATGCCATTGCCGAGCTGATCGAGGCGCGCGCC
GTCGATCGCGCGCGCAACGCCATCCAGGGCCTGCTGGCGCTGACGCCCGAACTGGCCGAGGTCAGGCAGCCCGATGGCCG
CTGGAAGACGGAGAAGGCCGATGCGGTGGCGCTCGATGCCGTCGTGCGCATCCGGCCCGGCGAACGCGTGCCGCTGGACG
GCGTGGTGACCGAAGGGGCGAGCGCCATCGACCAGGCGCCGGTCACGGGCGAGAGCATTCCGGTCGACAAGGCGGTGGGA
GACGCGGTGTTCGCAGGCACCATCAACCAGACGGCCGCGCTCGAATTCCGCGTCACCGCGGTGGCGGCCAACACCACGCT
CGCGCGCATCATCCATGCGGTCGAAGAGGCGCAGGGCACGCGCGCGCCCACGCAGCGCTTCGTCGACCGGTTCGCGGCCG
TCTACACGCCCGCGGTCTTCGTGCTGGCCATTGCCGTGGCGCTGCTCACGCCCTGGCTCATGGGCTGGAGCTGGACCGAG
GCCATCTACAAGGCGCTGGTGCTGCTGGTCATTGCGTGCCCGTGCGCGCTGGTCATCTCGACGCCCGTCACGGTGGTGAG
CGCGCTGGCCTCGGCCGCGCGGCGCGGCATCCTGATCAAGGGCGGCACCTATCTCGAAGAGGCGCGCAGGCTCAAGGCCG
TGGCACTCGACAAGACCGGCACCATCACCGAAGGCAAGCCGAAGCTGGTCGCATCGCGCCTGCTCGACCCCGCGGCGGAT
GAAGCCGCGATCTTTGCCATTGCCGCGAGCATCGCGGGCCGCTCCGACCATCCGGTGTCGAAGGCCATTGCCGACGGGCT
GAACCGCGAGCACCAGCCGGTCGGCGGCTTCACGGCCTTGCCCGGACGCGGCGTGCAGGCCGTGCACGAAGGCCGCAGCT
ATGTGCTTGGCAACCACCGCCTGATCGAAGAGCAGGGGCTGTGCAGCCCCGCGCTCGAAGCCGAGCTGAAGCAGCATGAG
GAAGCGGGGCGCACCGTCACGCTGCTGGCCTCCGGCCAGGCCGTGCTGGCGCTGTTCGCGGTGGCCGACACCATCAAGCC
CTCTTCGAAGGCCGCCATGGCCGAGCTGCGCGCGCTGGGCGTCACGCCCGTGATGCTGACCGGCGACAACGCCGCCACGG
CCAGGGCGATCGGCCTGCACGCGGGCATCGACGACGTGCGCGGCAACCTGCTGCCCGAGGAGAAGCTCGATGCCATCAAG
ACGCTGCAGCAGCGCCACGGCATGGCCGGCATGGCGGGCGACGGCATCAACGATGCGCCCGCGCTTGCGCAGGCCGACAT
CGGCTTTGCGATGGGCGGCGCCGGCACCGACACCGCCATGGAAGCGGCCGACGTGGTCATCATGAACGACGACCTGCGGC
GCCTGCCCGAAACCATCCGCCTCTCGCGCCATGCGCATGCGGTGCTGTGGCAGAACATCACGCTCGCGCTCGGCATCAAG
GCCGTGTTCTTCGTGCTCGCGGTGTTCGGCAGCGCCACCATGTGGATGGCGGTGTTTGCCGACATGGGCGCCAGCCTGCT
GGTGGTGGCCAACGGATTGCGGCTGATGCGCGCACCGAAGGGCGGCTGA

Protein sequence :
MGFMTNQNALKPMAPHAHSHAPAAPETACCGSTACGSPAVAVAAADIPKGALLFRIPTMDCAVEESEIRRALEPVAGVRG
LRFRLGERTMAITADEGALPGALDAIRKAGFKPEPLNGAAGSPADGAQPVAASAGIAGMSSGLVRLVAALVLAIAAEAVA
FLAPEGAGSMAAEMGLALAAIALAGLDTYKKGFAALLRGRLNINALMAVAVTGAFLIGQWPEAAMVMALYAIAELIEARA
VDRARNAIQGLLALTPELAEVRQPDGRWKTEKADAVALDAVVRIRPGERVPLDGVVTEGASAIDQAPVTGESIPVDKAVG
DAVFAGTINQTAALEFRVTAVAANTTLARIIHAVEEAQGTRAPTQRFVDRFAAVYTPAVFVLAIAVALLTPWLMGWSWTE
AIYKALVLLVIACPCALVISTPVTVVSALASAARRGILIKGGTYLEEARRLKAVALDKTGTITEGKPKLVASRLLDPAAD
EAAIFAIAASIAGRSDHPVSKAIADGLNREHQPVGGFTALPGRGVQAVHEGRSYVLGNHRLIEEQGLCSPALEAELKQHE
EAGRTVTLLASGQAVLALFAVADTIKPSSKAAMAELRALGVTPVMLTGDNAATARAIGLHAGIDDVRGNLLPEEKLDAIK
TLQQRHGMAGMAGDGINDAPALAQADIGFAMGGAGTDTAMEAADVVIMNDDLRRLPETIRLSRHAHAVLWQNITLALGIK
AVFFVLAVFGSATMWMAVFADMGASLLVVANGLRLMRAPKGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-118 45
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-118 45
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 3e-116 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Vapar_3562 YP_002945445.1 heavy metal translocating P-type ATPase BAC0298 Protein 2e-153 62
Vapar_3562 YP_002945445.1 heavy metal translocating P-type ATPase BAC0461 Protein 6e-79 42