Gene Information

Name : hemC (Vapar_1374)
Accession : YP_002943291.1
Strain :
Genome accession: NC_012791
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 1496533 - 1497459 bp
Length : 927 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTACTTTTTGGGAGCGGCCTTGAGCAATATCGTGATCGCCACGCGCGAAAGCCGGCTCGCCCTGTGGCAAGCCGAGCA
CGTGCAGGCGCTGCTGCAGGAACGGGGCCACGCGGTCAGCCTGCTGGGCATGACCACGCGCGGCGACCAGATCCTGGACA
AGTCGCTCAGCAAGGTGGGCGGCAAGGGCCTCTTCGTGAAGGAACTCGAACTCGCGCTCGAGGAAGGCCGCGCCGACATC
GCGGTGCATTCGCTGAAAGACGTGCCGATGGACCTGCCCGAGGGCTTCGTGCTGGCCTGCGTGCTGGAGCGCGAAGACCC
GCGCGATGCGCTGGTGTCGCCGCGCCATGCCTCGCTCGACGAGCTGCCGCAGGGCGCTGTCGTCGGCACCTCCAGCCTGC
GGCGCGTGGTGCTGCTGCGCGCCTTGCGGCCCGACCTGCGCATCGAGCCGCTGCGCGGCAACCTCGACACCCGCCTGCGC
AAGCTCGACCAAGGCCACTACGACGCTATCGTGCTCGCGGCGGCCGGGCTCAAGCGGTTGGGGCTCGAGCATCGCATCCG
GGTCGCCTTCGATCCCGACACGATGCTGCCGGCCGCGGGGCAGGGCGCACTCGGCATCGAAGTGCGGGCCGACCGCACGG
ACCTGATCGCGCTGCTGGCCGCCTTGTCGCACTCGCGCGATTGGCTGGCCACCGCCGCCGAGCGCGCGGTGAGCCGGTCG
ATGGGCGGCAGCTGTTCCATGCCGCTGGCGGCCCATGCGCGCTGGCAGGCCGACGGTGCGCTGCGCGTCGATGCGGCTTG
GGGCGACCCCGAAGGCAACGCTGCGCTGGTGCGGGTCCATGCGCAAGCGCCGGCCGCCGACTTCGCGCAGGCCGGCGCCC
TCGGCGAGCGTGCCGCCGCGCTGCTGCGCGACGCCGGCGCGCACTGA

Protein sequence :
MYFLGAALSNIVIATRESRLALWQAEHVQALLQERGHAVSLLGMTTRGDQILDKSLSKVGGKGLFVKELELALEEGRADI
AVHSLKDVPMDLPEGFVLACVLEREDPRDALVSPRHASLDELPQGAVVGTSSLRRVVLLRALRPDLRIEPLRGNLDTRLR
KLDQGHYDAIVLAAAGLKRLGLEHRIRVAFDPDTMLPAAGQGALGIEVRADRTDLIALLAALSHSRDWLATAAERAVSRS
MGGSCSMPLAAHARWQADGALRVDAAWGDPEGNAALVRVHAQAPAADFAQAGALGERAAALLRDAGAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-54 54
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-54 54