Gene Information

Name : Kole_0854 (Kole_0854)
Accession : YP_002940568.1
Strain : Kosmotoga olearia TBF 19.5.1
Genome accession: NC_012785
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 902206 - 903480 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATAGATATCCGTCTTGTGCGTGAGAATCCGGAAAAAATAAGGGCGGCTTTGAAGAATAGATGTGTAGATGAATCTAT
ACTCGATGAATTGCTCGAGTTAGATAAGGCAAGACGCGAAGCTATAAGTACTTCCGATAGGAAAAAAGCGGAGAGGAACA
AGATATCTTCACAGATCGCAAAAGCAAAAGCTTCAGGTGATGAAGCTCTGGCTAAAGAGCTCATGGAAAAGGCAAAGGAC
ATCTCTGTTGAGGTAAAAGAACTTTCTGAAAAGGCGAAGAAACTCGATGAAGAAATGAGAAATAAATTGCTTTACATACC
GAACATTCCTCACGAGAGCGTTCCTGTGGGCGAAAGTGAGGAAGACAATGTTGTTGTTAGAAAATGGGGTGAGCCAAGAC
AATTTGATTTTGACTCCCTCGCACATTGGGATCTTGGTCCCAATCTTGGTATGATGGATTTCGAACGAGCAGCGAAGTTA
AGTGGTTCGAGATTTGTAATTCTAAGGAAAGAACTGGCCAGGCTCGAGCGCGCTCTCATTAACTTCATGCTCGATCTTCA
TACTAGAGAGCACGGTTACGAAGAAGTTGCTTTGCCACACCTCGTAAAAAGGGAAACAATGCAAGCCACAGGGCAGCTTC
CAAAATTCGAGGAAGAAGCTTATAAAACCGATCCGGACGATATGTTCCTGATACCAACAGCTGAAGTTCCTCTTGTAGCA
CAGCACAGGGACGAAATTCTTAACCTGAACGAACTTCCGAGGAAATATACAGCTTATACCCCGTGTTACAGAAGAGAAGC
TGGAAGCTATGGAAAAGACGTGAAGGGAATGATAAGGGTACACCAGTTTGACAAGGTGGAACTTGTCTGGTTTGTTCATC
CAGATGAATCTTACGAAGCCCTTGAAAAGCTTACCGCTGATGCGGAAGAGGTTCTCAAAAGACTCGGGCTTCCATACAGA
GTAGTGGCTTTGTGTACAGGGGACCTCGGTTTTGCTGCGGCTAAAACCTATGATATAGAAGTCTGGCTGCCATCTTACAA
CGCTTACAAAGAAATCTCGTCATGCAGTAATGTTGAGGATTTCCAGGCGAGAAGGGGAAATATGCGCTTTAGAGATAAAG
ACAATAAATTGAAATACGTCCACACCCTCAATGGGTCTGGGCTTGCTGTTGGAAGGACTCTGGTTGCCATCGTTGAGAAC
TATCAGCTTCCGGATGGAAGGATAAGAGTTCCAGAAGTCCTGGTTCCTTATATGGGAACGGAGGTAATAGGCTGA

Protein sequence :
MIDIRLVRENPEKIRAALKNRCVDESILDELLELDKARREAISTSDRKKAERNKISSQIAKAKASGDEALAKELMEKAKD
ISVEVKELSEKAKKLDEEMRNKLLYIPNIPHESVPVGESEEDNVVVRKWGEPRQFDFDSLAHWDLGPNLGMMDFERAAKL
SGSRFVILRKELARLERALINFMLDLHTREHGYEEVALPHLVKRETMQATGQLPKFEEEAYKTDPDDMFLIPTAEVPLVA
QHRDEILNLNELPRKYTAYTPCYRREAGSYGKDVKGMIRVHQFDKVELVWFVHPDESYEALEKLTADAEEVLKRLGLPYR
VVALCTGDLGFAAAKTYDIEVWLPSYNAYKEISSCSNVEDFQARRGNMRFRDKDNKLKYVHTLNGSGLAVGRTLVAIVEN
YQLPDGRIRVPEVLVPYMGTEVIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-98 53