Gene Information

Name : Kole_0404 (Kole_0404)
Accession : YP_002940133.1
Strain : Kosmotoga olearia TBF 19.5.1
Genome accession: NC_012785
Putative virulence/resistance : Resistance
Product : Cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 425938 - 427125 bp
Length : 1188 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: bha:BH0799 methionine gamma-lyase

DNA sequence :
GTGGAAAATAAAGATCTTCATTTTGATACTCTTGCGATACATGCGGCTGAAAAAACCGATCAAAATCAAGCATTAAATCC
ACCTATATACATGACCTCGACGTTCACTTTTACGGACTTACAGCAAGCTGACGATACATTCAGCTTCAAACGAAAGGCAT
TTGTTTATACCAGAGGTGGGAATCCAACGATAAACCTTTTTGAAGCTAGAATGGCTGCTCTGGAATCCGGTGTTGATTCC
GTAGCCTTTGCTTCTGGTATGGCGGCTATAACTTCTGTTTTGTTGTCCTTTGTTAAAAATGGTGATGAAATCCTTGCGCA
CAGAAACCTCTATGGTTCAACTTTTGGGGCTACCGCGCATCTTTTTCCGAATTATGGAATAATTACACGCTATGTGAACA
TGTCAGACTTAAAACAAGTTGAAAAGAGTATCACCCCAAAAACAAAGGTGCTTTATCTTGAAACTCCAACAAATCCATCT
CTGGAGATAATTGATATTGCTGAGTTATCTAAAATCGCAAGAAATTATGGCATCAAAGTTGTTGTGGATAACACCTTTGC
AACACCGTACTTTCAGAAACCCCTCGAACTTGGGGCTGACGTTGTTGTTCATAGTGCAACAAAATATATTTCCGGTCATG
GGGACGTTGTTGCTGGTGTAGCAATTTCTAAAGATCAGGAGTACATTCACAGATTAAAGTTTGGCTATATGTGCGAATTG
GGAGGTGTTTTGAGCCCATTTAATGCCTGGCTCCTCTTAAGGGGATTAAAAACACTTTCATTAAGAATGAAACGGCATGA
GGAGAACGCTATGGCAATTGTGCGATATCTCAAAAATCATCCTCTCGTTGAAAAGATCATGTATCCCGGGTTAGAAGAAC
ATCCTGGCCATGAGCTGGCAAGAAAACAAATGACTGGATTTGGTGGTATTGTCAGCTTTGAACTCAAAGGTGACGTGGAA
ACGGCGAAGGCTTTTGTTCGCAACCTTAAGCTTATAAAACTTGCTGTTAGCCTCGGGGACGCTGAAACCCTCGTTGAAGT
TCCAGCTCTTATGACTCATAGGGATTATCCCGAAGAAAAACTGCACGAGTTTGGATTCTCGAGAAAAACCGTGCGAATAT
CTACCGGATTGGAACACCCGGATGATCTTATAGAGGATATCGAGAGAGCCCTTAAAGGAGTTGAGTGA

Protein sequence :
MENKDLHFDTLAIHAAEKTDQNQALNPPIYMTSTFTFTDLQQADDTFSFKRKAFVYTRGGNPTINLFEARMAALESGVDS
VAFASGMAAITSVLLSFVKNGDEILAHRNLYGSTFGATAHLFPNYGIITRYVNMSDLKQVEKSITPKTKVLYLETPTNPS
LEIIDIAELSKIARNYGIKVVVDNTFATPYFQKPLELGADVVVHSATKYISGHGDVVAGVAISKDQEYIHRLKFGYMCEL
GGVLSPFNAWLLLRGLKTLSLRMKRHEENAMAIVRYLKNHPLVEKIMYPGLEEHPGHELARKQMTGFGGIVSFELKGDVE
TAKAFVRNLKLIKLAVSLGDAETLVEVPALMTHRDYPEEKLHEFGFSRKTVRISTGLEHPDDLIEDIERALKGVE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-56 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kole_0404 YP_002940133.1 Cystathionine gamma-lyase BAC0207 Protein 3e-79 49