Gene Information

Name : Kole_2041 (Kole_2041)
Accession : YP_002941723.1
Strain : Kosmotoga olearia TBF 19.5.1
Genome accession: NC_012785
Putative virulence/resistance : Virulence
Product : ATPase AAA-2 domain protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2167880 - 2170366 bp
Length : 2487 bp
Strand : +
Note : PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Torsin; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: baa:BA_0670 Clp_N, Clp amino terminal domain

DNA sequence :
ATGTATTTCGATAAATTTTCTGAGGGAGCCGCACAGGTATTTGTAGCTGCCCAGGATGAAGCAAGGAGCCTGGGGCATCC
ATATGTTGGGACGGAACACTTATTGCTCGCTATATTAAAGGTGAACTCTGGAACCACTTCTCAATTACTCAAGGGATACT
CCATAACGTATGAGCGTGTTCTGAGGGAAGTAACATCTATGGTTGGAACGAACATTCGGCAATCAGTGGTTGGTTCCCCT
CAAATGACTCCACGTGCCAGACGCGTCATCGAGCTGGCCAATGACGAGTCAAGAATGCTGGGACAGGACAAAATAGATGT
TGAACATATAATGTTAGGTATAGTTCGCGAAGGTGAAGGAATAGCTGCTCACATCTTGAAACAGATGGGTGTCAATCTTG
GCAAACTGAGAAAACAACTTATAGAAAATATTACGAGTGACTGGGACGAGTCTACAACGGGCGGACGTTCTTTCGGTGCT
CAGCAATCAAGCATGGCTACTTCTTTGAAACAACTGGAAGGATTTGGAACGGATTTGACCGCTCTGGCGCGTGCGGGAAA
ACTCGACCCCATAATCGGACGTGATGTTGAAAAGCAGAGATTAATGGAAGTGCTCTCCAGGAGGAAGAAAAACAACCCCG
TTCTCATAGGAGATCCGGGTGTAGGAAAGACCGCTATCGTGGAAGGACTCGCGCAGATGATTGTCAATGAAGAGGTTCCA
GAGACCTTGAAAAATAAAGCAATTTTTGCTCTTGATGTTGCTTCGTTGATTGCCGGTACAAAATACCGTGGAGAGTTTGA
AAAGCGTTTGAAGAAGCTCATACAGGTTGTAAAGAATAATGGGAACATAATCCTTTTCATTGATGAACTTCACACGATAG
TTGGTGCTGGTTCTGCCGAGGGTGCTGTCGATGCCGCTAATATATTGAAACCAGCTCTGGCAAGCGGCGAGATAAGATGT
ATAGGTTCTACAACTCCTGATGAATACAGAAAATACGTTGAAAAGGACGCTGCCCTGGAAAGACGTTTCCAGAAGATTTA
TGTTTCTGAACCCACGGTCGAGCAGACAATCGGAATTCTGAGAGGCATCAAGCACAAATATGAGGCACATCATAAGGTCT
ACTATACTGATGCCGCGTTGGAAGCTGCTGTTTTATTGTCTCACAGGTATGTCAGTGACCGCTTCCTCCCGGATAAAGCG
ATAGACATTATCGATGAAGCTGGTGCACGTGCCAGACTTAGAAAACTAACTGTACCATCTTATTTGAAAGAACTTCAGAA
AAAGATAGAGAAGCTCAGGCTTGAGCGAGAAGACGCGGTTTCTCGACAGGATTACGAGCATGCAGCAGAACTAAAAGAAG
AAGAAAGGGTTTTGATGAAAACCTATAAGGACGAATACAATAATTGGCGTGAGAAGGTTGACTCAGAAATTGTTCAAATA
AGTGAAGAAGAGGTTGCTGAGATTGTTTCTAGCTGGACCGGTATCCCGCTGAAGAAGTTGGAGCAGTCGGATAGCGAAAG
ACTCCTTTCACTGGAAGAGGCTCTTCACAAACGAATCGTCGGCCAGGATGAAGCAATAACGGCAGTTGCAAAAGCCATAA
GAAGAGCAAGAAGTGGGCTTAAAGATCCCAGACGGCCCATCGGTACCTTCCTGTTCCTTGGACCTACCGGGGTCGGGAAA
ACGGAGTTAGCAAAGGCTCTTGCCGAATACCTTTTTGGCGATGAAAAGGCTCTCGTCAGATTCGATATGTCTGAGTATAT
GGAAAGGTTCTCTGTGTCTCGTTTGATCGGGGCACCACCGGGATACGTTGGATATGATGAAGGTGGAACACTCACCGAAA
GAATAAGGAAGCGTCCTTTTTCCATTATTCTTTTCGATGAAATCGAAAAAGCCCATTTCGACATTTTCAATCTACTCCTC
CAGATCATGGATGATGGCCGTCTTACTGATTCTCAGGGTCGCAGCGTTGACTTCAAAAACACAATAGTCATAATGACCAG
CAACCTTGGTGGTGAGTTTATTAACAAGACGAAGAAAACACTGGGGTTTGTAAGTGCGGCAAATGTTGAGGAAAAAGAGT
ATGAATCGATGAAAAACTCCGTTCTTGAAGAAGTGAAGAAAACCTTCAGGCCTGAGTTTTTGAACAGGCTGGACGAAATC
GTCGTCTTCCATCCGCTGACGAGAGAGCAGATCAAGAAGATTATCGAGATTCTCATTTCGGATACGAGAAAACGGCTTAA
AGAAAAGAAAATGGACCTAGTATTATCTGAAGCAGCTCAGGAGTTCCTTGTTGAGAAAGGGTTTGATCCTGTCTACGGTG
CGCGGCCATTACGTAGAGCAATTCAGAGATACATAGAAGACCCTCTCGCGGAGGAGGTGCTCAGAGGTAGATTTGAGCCT
GGTGACACAATAATGGTTGTAAGGCAGGATGAAAAACTTTCCTTTAAAAAGAGCAAGAAGAAGGTTGAGGTAAAAGCTGG
AACATGA

Protein sequence :
MYFDKFSEGAAQVFVAAQDEARSLGHPYVGTEHLLLAILKVNSGTTSQLLKGYSITYERVLREVTSMVGTNIRQSVVGSP
QMTPRARRVIELANDESRMLGQDKIDVEHIMLGIVREGEGIAAHILKQMGVNLGKLRKQLIENITSDWDESTTGGRSFGA
QQSSMATSLKQLEGFGTDLTALARAGKLDPIIGRDVEKQRLMEVLSRRKKNNPVLIGDPGVGKTAIVEGLAQMIVNEEVP
ETLKNKAIFALDVASLIAGTKYRGEFEKRLKKLIQVVKNNGNIILFIDELHTIVGAGSAEGAVDAANILKPALASGEIRC
IGSTTPDEYRKYVEKDAALERRFQKIYVSEPTVEQTIGILRGIKHKYEAHHKVYYTDAALEAAVLLSHRYVSDRFLPDKA
IDIIDEAGARARLRKLTVPSYLKELQKKIEKLRLEREDAVSRQDYEHAAELKEEERVLMKTYKDEYNNWREKVDSEIVQI
SEEEVAEIVSSWTGIPLKKLEQSDSERLLSLEEALHKRIVGQDEAITAVAKAIRRARSGLKDPRRPIGTFLFLGPTGVGK
TELAKALAEYLFGDEKALVRFDMSEYMERFSVSRLIGAPPGYVGYDEGGTLTERIRKRPFSIILFDEIEKAHFDIFNLLL
QIMDDGRLTDSQGRSVDFKNTIVIMTSNLGGEFINKTKKTLGFVSAANVEEKEYESMKNSVLEEVKKTFRPEFLNRLDEI
VVFHPLTREQIKKIIEILISDTRKRLKEKKMDLVLSEAAQEFLVEKGFDPVYGARPLRRAIQRYIEDPLAEEVLRGRFEP
GDTIMVVRQDEKLSFKKSKKKVEVKAGT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kole_2041 YP_002941723.1 ATPase AAA-2 domain protein VFG0079 Protein 0.0 54
Kole_2041 YP_002941723.1 ATPase AAA-2 domain protein VFG0080 Protein 3e-147 47