Gene Information

Name : Kole_1913 (Kole_1913)
Accession : YP_002941598.1
Strain : Kosmotoga olearia TBF 19.5.1
Genome accession: NC_012785
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 2034105 - 2036567 bp
Length : 2463 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGAAAATTTTAGGAAAGCTTTTCGACAAGAACAAAAGAACTTTGAAAAGATACGATTCCATTGTAAAAAAAGTGAATGC
TCTGGAAAAAGAAGTCAGGGAATACCCGGCAGAAAAATTTCCTCAGAAGACCCGTGAATTAAAAGAGAGGATAAAAAAGG
GAGAACCATTGGATAATCTTTTGCCTGAAGCTTTTGCTCTTGTTCGTGAAAGTGCCAGAAGAACGGTTGGTATGAGGCAT
TTTGACGTCCAGGTAATGGGCGCCATAGCTCTCCACGAGGGAAAGATAGCCGAAATGAAAACCGGAGAAGGAAAAACCCT
GGTAGCAACCATGCCCCTCTATCTGAACGCCTTGACCGGGAAAAACGTTCAACTCGCCACAGTCAACGACTACCTGGCAA
GAAGAGATGCGGCGTGGATGGGACCAGTCTATGAATATCTAGGATTAACCGTTGGATACATACAATCATCCATGGATACA
TCAGATCGAAAAAAAGCCTATCAATCCGATGTAACTTACGGTACTGCCAACGAATTTGGATTCGATTATTTGCGCGATAA
TCTTGTCTACTCATTAGAACAAAAAGTGCAAAGAGACCACTACTACGTTATCGTTGACGAAGCTGATAGCATCTTGATAG
ACGAAGCCAGAACACCTCTGATCATTTCGGGACCAGCAGAGGCATCTTCAGAACTATACAGAAAATCCGCCTTCTATGCC
AGACGCTTTGTGGAAAATGAAGATTTTATCGTAAATGAAAAAGAAAAAACGGTCAGTCTTACCGATAAAGGAATAGAAAA
AGCCGAGAGACTCTTCGGGATTGATAATCTCTACGACCCAAATAATTATACTTACCTTTTCCATCTTTTGAATGCCTTAA
AAGCCCGAACTCTTTTTAAAAAAGATGTGGATTACATCGTATCCAACGGGGAAGTCATTATCGTCGACGAATTCACCGGA
AGACTTCTTCCAGGAAGACGTTACAGTGAAGGATTGCACCAAGCCATCGAAGCAAAAGAAAATGTCAAGATAAAAGAAGA
AAGCATTACTTATGCCACTATCACCTTCCAGAACTACTTCAAGATGTATGAAAAACTCGCGGGGATGACAGGAACGGCTG
CTACCGAAGAAGCCGAATTCGTATCAATATACGGTTGTGAGGTAGTGGTTATACCGACAAACAAACCAGTTCTCAGAAAA
GACAAAGATGATCTCGTCTTCCGTACTGTAGAAGAAAAATACGCTGCTATTGTTGAGGAAATAGAAAAACGCTATAAGAA
AGGCCAACCTGTTCTTGTTGGAACAACTTCTATAGAAAAGAGTGAATATCTGAGCTCTTTGCTTAGAAAAAAAGGCATTC
CACATGAAGTCTTAAATGCCAAGCACCACGAAAGAGAAGCAGAAATAGTAGCCAAAGCTGGTGAAAAAGGTACTGTAACC
ATCGCTACGAATATGGCCGGTAGAGGAACCGATATAAAGCTTGGTGAGGGTGTCAAAGAACTTGGCGGATTATTCGTTCT
TGGAACGGAGCGTCATGAAAGTCGAAGAATAGACAACCAGCTCATCGGTCGTTCCGGAAGGCAAGGGGATCCCGGAGAAT
CGAGGTTCTTCCTATCCCTCGAAGATGACTTGATTCGTCTTTTTGGCGGAGAAAAGCTCAAAGGTATTATGGACACCCTC
AAAATAGAAAAAGGTGAACCAATCGAACATCCATTGCTGAGTAGAATAATCAACTCCGCTCAGAAAAAAATCGAAGGTAT
TCATTTCTCAATACGAAAACGCCTTTACGAGCTAGACTCTGTTGTAGATAAACAAAGGAGTGCTATTTACGCCCACAGGG
ATTGGCTCCTTAGAGGTGAAGACATCGATAAACATATCCATGAAATCATAGAGGATACGGTTACTCGCAGAACAGAAAAT
TGGGAAACTGTTCCCGCATATGAAGAGATAAAAACTTCCTTCGGCTTTCTACCTGAACGAATCCTGGAAGGTGTTAAAAG
CTGCAAAAAACCTGAAGAGTTAACCAATATACTCATAGAAAACCTGAAAAAAGAGTATGAAGAAAAGAAAAAAGCCTTTG
GCGATGAGTTCCCCAATGTGCTGAAATATTTAATGCTTCGCATGATAGATGAACGCTGGAGAAAACACCTGGAAGCAATA
GAACATTTGAAGGACTCGGTGGGTTTAAGGGCTTACGGACAAAAGGATCCTGTGATAGAATTCAAAAAAGAATCCTATAT
ATTGTTTGAAGAAATGGTCGATTCGTTGTACGATGACATTGTCAGCGTACTGGTAAGATTGATCAGAATAGATAGCGAAA
AAACAAGAGAGAAAGCGCAGAAAGAGCTACAAAAGTTGAATTTCGTTCATAATGAATTTTCTGCCCTCAAAAAAGATGGC
GGTAAACGTTCTAAAGAGAAAAAGCACGGTACTCATAGCAGAAGATTCAAAGTAAAACGTTGA

Protein sequence :
MKILGKLFDKNKRTLKRYDSIVKKVNALEKEVREYPAEKFPQKTRELKERIKKGEPLDNLLPEAFALVRESARRTVGMRH
FDVQVMGAIALHEGKIAEMKTGEGKTLVATMPLYLNALTGKNVQLATVNDYLARRDAAWMGPVYEYLGLTVGYIQSSMDT
SDRKKAYQSDVTYGTANEFGFDYLRDNLVYSLEQKVQRDHYYVIVDEADSILIDEARTPLIISGPAEASSELYRKSAFYA
RRFVENEDFIVNEKEKTVSLTDKGIEKAERLFGIDNLYDPNNYTYLFHLLNALKARTLFKKDVDYIVSNGEVIIVDEFTG
RLLPGRRYSEGLHQAIEAKENVKIKEESITYATITFQNYFKMYEKLAGMTGTAATEEAEFVSIYGCEVVVIPTNKPVLRK
DKDDLVFRTVEEKYAAIVEEIEKRYKKGQPVLVGTTSIEKSEYLSSLLRKKGIPHEVLNAKHHEREAEIVAKAGEKGTVT
IATNMAGRGTDIKLGEGVKELGGLFVLGTERHESRRIDNQLIGRSGRQGDPGESRFFLSLEDDLIRLFGGEKLKGIMDTL
KIEKGEPIEHPLLSRIINSAQKKIEGIHFSIRKRLYELDSVVDKQRSAIYAHRDWLLRGEDIDKHIHEIIEDTVTRRTEN
WETVPAYEEIKTSFGFLPERILEGVKSCKKPEELTNILIENLKKEYEEKKKAFGDEFPNVLKYLMLRMIDERWRKHLEAI
EHLKDSVGLRAYGQKDPVIEFKKESYILFEEMVDSLYDDIVSVLVRLIRIDSEKTREKAQKELQKLNFVHNEFSALKKDG
GKRSKEKKHGTHSRRFKVKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-108 48