Gene Information

Name : Kole_1625 (Kole_1625)
Accession : YP_002941319.1
Strain : Kosmotoga olearia TBF 19.5.1
Genome accession: NC_012785
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1743675 - 1745093 bp
Length : 1419 bp
Strand : +
Note : KEGG: bha:BH3163 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta

DNA sequence : 
ATGAGGAAGACGAAAATAGTTTGTACTGTTGGGCCGGCAACAGAAAATCCCGATATGTTAAAAAAACTCATAGAAGCTGG
CATGAATGTGGTGAGATTAAACACTTCGCATGATGATTTAGAACATCATCGTCGGAGAATTAGAACAGTTAAGAAAATTC
GTGAAGAACTTGCTGTGCCTATCACTATATTACTTGACCTTGCCGGCCCAAAGATAAGGACGGGAGACTTTTCTTCAGAT
ACGGTTGTTCTTAAGAAAGGAGACCTATTCACTCTCACGACAGAGGATATTGTTGGTGATGATAAGCGAGTGAGTGTAAG
TTACAAAAAACTACCATCTGAAGTTAATTCTGGAGACTTCATCCTCGTAAACGACGGAAAAATAAAGTTGAAGGTTGTAG
AAACGAACGAGACAGAGATAAAAACCACCGTCGTTAACGGTGGGGAAATAACGCACCGTAGAGGAATAAACGTTCCTGGA
ATCGATCTTGGAATAGAAGCTCTTACTTTAAAGGATAAGGAATTTATAAAGTTGGGCATCGAAGAAGGCGTAGACTACTT
TGCACTGTCTTTTGTCAGGAAACCCGAGGATGTTATCGAAGCTAAGAAGATCATTTCAAGCTTTGGTGGCAGCATTCCGA
TAATTTCGAAAATAGAAACAGTGCAGGCTCTAAAAAGAATAGAGTCTATCGCTGAGGTCTCAGATGGTCTTATGGTAGCT
CGGGGTGATCTTGGTGTCGAAATTCCTGTGGAAGAAGTTCCAATAGCTCAAAAAAAGATAATACGCGCAGGAAATAAAAA
TAGAATCCCGGTAATAACAGCTACTCAAATGCTTGAATCAATGATAGAAAACCCTGTTCCTACAAGAGCAGAGACCACGG
ACATCTCCAATGCAATAATCGATGGAACCGATGCGGTGATGCTCTCAGCCGAAACCTCTGTTGGCAAATATCCTATCGAA
GCAGTGAGTGTAATGCATAAAACCGCATTGTCCACAGAAAAGTATATTCGTGCCCACCCCTATCTTCTCCAATGGACTCG
CGAAGATGTTGTCACCGACGACCATACGGACGCTATATGCCGCGCGGCGTGGGATATAAGCGAAACATTAAAAATAAAGC
TTATCGTTTCGTCTACCTATACAGGGCACACGGCAATAAACGTTTCCGGTTTCAGACCACGTTCGCACATTCTGGCAGTT
ACCCCAAACAAGAATACGTACCACCGCCTTGGAATGGTCTGGGGTGTAACACCCATGCTATTAGAGCTCGGTTCAACGAT
AGACGAAATGGTGAAGATTGCCAGTGAAAAGGCCAGAAAGCTCGACCTTCTTGATCCGGGAGATAATTTCATAATCACTG
CTGGTGTTCCACTTGGCAAGGCTAACACTACCAATATGTTGAAACTCGAAAGAGCTTAA

Protein sequence : 
MRKTKIVCTVGPATENPDMLKKLIEAGMNVVRLNTSHDDLEHHRRRIRTVKKIREELAVPITILLDLAGPKIRTGDFSSD
TVVLKKGDLFTLTTEDIVGDDKRVSVSYKKLPSEVNSGDFILVNDGKIKLKVVETNETEIKTTVVNGGEITHRRGINVPG
IDLGIEALTLKDKEFIKLGIEEGVDYFALSFVRKPEDVIEAKKIISSFGGSIPIISKIETVQALKRIESIAEVSDGLMVA
RGDLGVEIPVEEVPIAQKKIIRAGNKNRIPVITATQMLESMIENPVPTRAETTDISNAIIDGTDAVMLSAETSVGKYPIE
AVSVMHKTALSTEKYIRAHPYLLQWTREDVVTDDHTDAICRAAWDISETLKIKLIVSSTYTGHTAINVSGFRPRSHILAV
TPNKNTYHRLGMVWGVTPMLLELGSTIDEMVKIASEKARKLDLLDPGDNFIITAGVPLGKANTTNMLKLERA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-75 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-74 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-74 42
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-74 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Kole_1625 YP_002941319.1 pyruvate kinase VFG0479 Protein 5e-75 42