Gene Information

Name : Kole_1432 (Kole_1432)
Accession : YP_002941128.1
Strain : Kosmotoga olearia TBF 19.5.1
Genome accession: NC_012785
Putative virulence/resistance : Unknown
Product : carbamate kinase-like carbamoyl phosphate synthetase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0549
EC number : 2.7.2.2
Position : 1527234 - 1528172 bp
Length : 939 bp
Strand : -
Note : this enzyme from Pyrococcus has carbamoyl phosphate synthetase activity even though the enzyme shows sequence and structural similarity to carbamate kinase; this enzyme using carbate and ATP to synthesize carbamoyl phosphate which may be a favorable react

DNA sequence :
ATGAAAAAAGCAGTCGTAGCTATCGGCGGCAACGCACTGAACAAGCCCGGCGAAAAGCCAAGCGCAGAGGCAATGAAGAA
AAATCTGCTTGGTACCGTCAAACATCTTGCAGATCTTATTGAAGACGGCTATGATCTGGTAATAACACACGGTAATGGCC
CACAGGTTGGAAATCTCCTTGTCCAGCAGGAAATTGCCAAGGACACATTACCACCATTCCCGATCGACGTAAATGATGCT
ATGACTCAAGGATCAATAGGTTATCTGATAACCCAAACTCTCGGCAACGAACTGAAAAGCCGGGGAACAGAAAGACAAAT
AGCCTGTGTTCTAACCCAGATAATCGTTGATAGAAACGATCCGGGTTTTGAAAACCCCACAAAACCAGTAGGACCATTCT
ACGATGAAGAAACCGCGAAAAAACTTCAAGCAGAAAAAGGCTGGATAATGAAAGAGGATGCCGGACGTGGCTGGAGGAGA
GTTGTCCCTTCCCCAAAACCTCTGGATGTAGTTGAGATTGAAGCAATCAAGGCTCTTACAGGAAATGATTTCATCCTCGT
AGCCGGCGGTGGCGGTGGAATACCCGTTGTAAAGAAAGATGACGGAACACTTGAAGGTGTAGAAGCCGTCATCGATAAAG
ATCGCGCTTCCGCTTTACTGGCAAGACTCCTAGATGCTGATCTCTTCCTGATTCTCACAGCCGTAGACCACGCTTACATC
AACTTCGGCAAACCTGATCAAAAAGCTCTCGAACGCATATCAGTCAACGAAGCCAAAAAATTGATGGATGAGGGTCACTT
TGCAAAGGGCAGTATGTATCCAAAAATAGAATCCGCCATTGATTTCGTGGAATCCACCGGAAAAGAGGCGATCATCACCT
CCCTGGAAAAAGTCAAAGAAGCAATTCAGGGAAAATCTGGAACACATATAACTAAGTAA

Protein sequence :
MKKAVVAIGGNALNKPGEKPSAEAMKKNLLGTVKHLADLIEDGYDLVITHGNGPQVGNLLVQQEIAKDTLPPFPIDVNDA
MTQGSIGYLITQTLGNELKSRGTERQIACVLTQIIVDRNDPGFENPTKPVGPFYDEETAKKLQAEKGWIMKEDAGRGWRR
VVPSPKPLDVVEIEAIKALTGNDFILVAGGGGGIPVVKKDDGTLEGVEAVIDKDRASALLARLLDADLFLILTAVDHAYI
NFGKPDQKALERISVNEAKKLMDEGHFAKGSMYPKIESAIDFVESTGKEAIITSLEKVKEAIQGKSGTHITK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0102 NP_763657.1 carbamate kinase Not tested SCCpbp4 Protein 2e-57 48
arcC1 YP_186045.1 carbamate kinase Not tested vSa¥ã Protein 2e-59 48
MW1051 NP_645868.1 carbamate kinase Not tested vSa¥ã Protein 2e-59 48
SAV1170 NP_371694.1 carbamate kinase Not tested vSa¥ã Protein 2e-59 48
SA1013 NP_374286.1 carbamate kinase Not tested vSa¥ã Protein 2e-59 48
arcC YP_493761.1 carbamate kinase Not tested vSa¥ã Protein 2e-59 48
SAKOR_01091 YP_008491279.1 Carbamate kinase Not tested vSa¥ã Protein 2e-59 48
APECO1_2636 YP_859422.2 carbamate kinase Not tested Not named Protein 1e-57 48