Gene Information

Name : EUBREC_2562 (EUBREC_2562)
Accession : YP_002938427.1
Strain : Eubacterium rectale ATCC 33656
Genome accession: NC_012781
Putative virulence/resistance : Virulence
Product : heat shock protein ClpB-like protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2435910 - 2438540 bp
Length : 2631 bp
Strand : -
Note : Cytoplasmic, score:9.98; COG0542 ATPases with chaperone activity, ATP-binding subunit; KEGG:K03695 heat shock protein ClpB-like; HMMPfam:IPR003959; HMMPfam:IPR004176; HMMPfam:IPR013093; FPrintScan:IPR001270; HMMSmart:IPR003593; ScanRegExp:IPR001270

DNA sequence :
ATGGATAACATAGTAGAAGGGAGTGAGACTATGAACATTCAAAAATTTACACAGAAATCAATAGAGGCAGTCAATGACTG
CGAGAAGCTTGCATATGATTATGGCAATCAGGAGATAGAACAGGAGCACCTGCTTGTGGCATTACTTTCACAGGAGGACG
GACTGATACCGAAGCTGATTGACAAGATGGAGATAAACGTAGAGCATTTCACAGAGAATGCAAAGCGCCATCTGGCAGCG
CGTACAAAAGTAAGCGGCAGCAGTGCACAGGTCTATGTGGGCAATGATTTAAACAAGGTTCTTATCCATGCTGAGGACGA
GGCAAAGGCAATGGGAGATGAGTATGTTTCGGTAGAGCATCTTTTCCTGTGTCTGCTGAAGTATCCAAACAAGGCAATGA
AGGAGCTGATAAAGGAGTATGGTCTCACAAGAGACAGATTCCTCACAGCACTTTCTACGGTCAGGGGCAATCAGAAGGTC
ACATCCGATAACCCTGAGGCCACATATGATACACTTGAGAAATATGGCTACGACATGGTGGAGCGTGCAAGACAGCAGAA
GCTTGATCCTGTTATCGGCCGTGATGATGAGATACGAAATGTAGTGCGTATTCTCTCACGTAAGACTAAAAATAACCCGG
TACTTATCGGTGAGCCGGGTGTTGGTAAAACGGCAGTCGTTGAGGGACTGGCGCAGCGTATCGTAAAGGGCGATGTGCCT
GAGGGCTTAAAGGACAAAAAACTGTTTGCACTCGATATGGGCTCTCTGATTGCAGGAGCTAAGTACAGGGGCGAGTTTGA
GGAGAGACTTAAGGCAGTGCTTGAGGAGGTAAAAGCCTCTGACGGACAGATAATTCTCTTTATCGATGAGCTTCACACAA
TAGTAGGAGCCGGAAAGACAGACGGAGCTATGGATGCAGGACAGCTTCTTAAGCCAATGCTTGCAAGAGGTGAGCTGCAC
TGCGTGGGCGCCACCACACTTGATGAGTACCGTGAGTACATTGAGAAGGATGCAGCTCTTGAGAGACGTTTCCAGCCTGT
TATGGTAGACGAGCCGACAGTAGAGGACACTATCTCAATACTTCGTGGTCTTAAGGACAGATACGAGGTATTCCATGGCG
TTAAAATCACAGATTCGGCACTTGTCACAGCGGCAGTGCTTTCAAACAGATACATCACAGACAGATTTTTGCCTGATAAG
GCAATAGACCTTGTGGATGAGGCATGCGCCATGATAAAGACGGAGCTTGATTCAATGCCGGCAGAGCTTGATGAGCAGAA
TCGTAAGATTATGCAGCTTGAGATAGAGGAGACAGCTCTAAAGAAAGAGACAGACCACTTAAGTCAGGACAGGCTCGCAG
CACTACAAAAGGAGCTTGCAGAGCTGCGTGATGACTTCAATGCGAAAAAGGCTCAGTGGCAGAACGAGAAGGGCGCTGTT
GACAAGGTCAGCAAGCTTCGTGAAAAGATTGAGTCCACAAAGAATGAAATCAAGACAGCGCAGCAGAACTATGACCTGGA
AAAGGCGGCAGAGCTGCAGTACGGCGTTCTTCCAAATTTGCAGAAGGAGCTGGAATCAGAGGAAGCACTGCTTAAGGACA
GGGATTTATCGCTTGTACGTGAGAACGTGGGCGATGAGGAGATTGCACTCATTATCTCGCGCTGGACAGGAATACCTGTT
GCAAAGCTTACGGAGAGTGAGCGTAATAAGACACTTCACCTCGATGAGGAGCTGCACAAGAGGGTAATAGGACAGGATGA
CGGAGTCACAAAGGTGACAGAGGCTATCATCCGATCAAAGGCAGGCATCAAGGATCCTACAAAGCCGATAGGTTCGTTTA
TGTTCCTCGGACCTACAGGTGTAGGTAAGACAGAGCTTGCAAAGGCACTTGCGGCAAGTCTTTTTGATGATGAGAACAAC
ATGGTCAGACTCGATATGAGTGAGTACATGGAGAAGTACTCAGTGTCACGACTCATCGGAGCGCCTCCTGGATATGTAGG
CTATGATGAGGGTGGACAGCTCACAGAGGCTGTAAGGCGTAAGCCATACTCAGTAGTACTCTTTGATGAGGTGGAAAAAG
CCCATCCGGATGTATTCAATGTGCTGCTTCAGGTGCTTGATGACGGACGAATTACTGACTCACAGGGACGTACCGTGGAT
TTCAAAAACACTATCATCATTATGACAAGCAACCTCGGCTCACAGGAGCTTCTTGAGGGTATAGAGGCAGACGGCAGCAT
CAGCACAGAGTGTGAGAACCGCGTCATGGATGAGCTTAAGGGTCATTTCAGACCGGAGTTTTTAAACAGACTTGATGAGA
TCATCATGTTCAAGCCTCTCACAAAGGATAACATTGGTCATATCATCACCTTGCTCATGGCAGACTTAAACAAGCGTCTT
GTCGACAAGGAAATCACAGTCGAGCTGACAGACACTGCAAAGCAGTTTATCACCGACAATGGCTACGATCCGGTATACGG
AGCAAGACCGCTCAAGAGATATCTGCAGAAGCATGTCGAGACACTCGCTGCAAAGCTGATTCTGGCAGATGGTGTGAGAG
CAGGAGATACCATTCTTATAGATGTGAAGGATGGCAAGCTTAGTGCATCGGCAGTTCAGAAAAATGCATAA

Protein sequence :
MDNIVEGSETMNIQKFTQKSIEAVNDCEKLAYDYGNQEIEQEHLLVALLSQEDGLIPKLIDKMEINVEHFTENAKRHLAA
RTKVSGSSAQVYVGNDLNKVLIHAEDEAKAMGDEYVSVEHLFLCLLKYPNKAMKELIKEYGLTRDRFLTALSTVRGNQKV
TSDNPEATYDTLEKYGYDMVERARQQKLDPVIGRDDEIRNVVRILSRKTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVP
EGLKDKKLFALDMGSLIAGAKYRGEFEERLKAVLEEVKASDGQIILFIDELHTIVGAGKTDGAMDAGQLLKPMLARGELH
CVGATTLDEYREYIEKDAALERRFQPVMVDEPTVEDTISILRGLKDRYEVFHGVKITDSALVTAAVLSNRYITDRFLPDK
AIDLVDEACAMIKTELDSMPAELDEQNRKIMQLEIEETALKKETDHLSQDRLAALQKELAELRDDFNAKKAQWQNEKGAV
DKVSKLREKIESTKNEIKTAQQNYDLEKAAELQYGVLPNLQKELESEEALLKDRDLSLVRENVGDEEIALIISRWTGIPV
AKLTESERNKTLHLDEELHKRVIGQDDGVTKVTEAIIRSKAGIKDPTKPIGSFMFLGPTGVGKTELAKALAASLFDDENN
MVRLDMSEYMEKYSVSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEVEKAHPDVFNVLLQVLDDGRITDSQGRTVD
FKNTIIIMTSNLGSQELLEGIEADGSISTECENRVMDELKGHFRPEFLNRLDEIIMFKPLTKDNIGHIITLLMADLNKRL
VDKEITVELTDTAKQFITDNGYDPVYGARPLKRYLQKHVETLAAKLILADGVRAGDTILIDVKDGKLSASAVQKNA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 8e-105 42
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-104 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 1e-104 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EUBREC_2562 YP_002938427.1 heat shock protein ClpB-like protein VFG0080 Protein 7e-143 45
EUBREC_2562 YP_002938427.1 heat shock protein ClpB-like protein VFG2076 Protein 4e-120 45
EUBREC_2562 YP_002938427.1 heat shock protein ClpB-like protein VFG2084 Protein 2e-113 41