Gene Information

Name : EUBELI_01260 (EUBELI_01260)
Accession : YP_002930704.1
Strain : Eubacterium eligens ATCC 27750
Genome accession: NC_012778
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit ClpB
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 1290796 - 1293393 bp
Length : 2598 bp
Strand : -
Note : Psort-B: Cytoplasmic, score:9.98; COG0542 ATPases with chaperone activity, ATP-binding subunit; HMMPfam:IPR003959; HMMPfam:IPR004176; HMMPfam:IPR013093; HMMSmart:IPR003593; ScanRegExp:IPR001270; K03695 ATP-dependent Clp protease ATP-binding subunit ClpB

DNA sequence :
ATGAACATTAATAAGTTTACACAGAAGTCTATTGAGGCTGTTAACCAGTGCGAGAAGATTGCCTACGATTATGGTAATCA
GGAGATTGATCAGGAACATTTTCTGTACAGTCTCTTAACTATAGAAGATAGTCTTATCGCGAGCCTGATAGAGAAGATGG
GAATTGATAAGGACACATTTATTAAGAATATTGAGACTTTACTTAGCCAGAAGAATAAGGTTTCAGGAAATGTACAGCTT
TATGTAAGCAATGATCTTAATAAGGTTTTAGTAAATGCTGAAGATGAAGCAAAGAGAATGGGGGATGCATATGTTTCTGT
TGAGCATCTTATGCTTGCGATGATTGCAGCACCTAACAAGGGTATAAAGCAGCTTTTTAAGACATATGGAATTAACAGGG
AATCATTCCTGTCAGCCCTTGCGACAGTAAGAGGTAACCAGAGTGTTACTTCGGATAATCCGGAGGCAACTTATGATACT
CTTAGCAAATATGCTACAGACCTTGTAGAAAGAGCCAAGGATGGAAAACTTGATCCGGTTATCGGAAGAGATAATGAAAT
AAGAAATGTAATAAGAATTCTTTCCCGTAAGACTAAGAACAATCCGGTTCTTATTGGTGAGCCAGGTGTTGGTAAAACAG
CAGTTGTTGAAGGACTTGCACAGAGAATTGTAAGAGGTGATGTTCCAGAAGGCTTAAAGGATAAGAAGCTTTTTGCACTG
GATATGGGCGCACTTGTTGCAGGTGCAAAGTATCGTGGTGAATTCGAGGAAAGACTTAAGGCTGTACTTGACGAGGTTAA
GAAATCTGAAGGACAGATAATTCTGTTTATTGATGAAATTCACACTATTGTCGGTGCAGGTAAGACAGAAGGTGCTATGG
ACGCAGGTAATATGTTAAAGCCAATGCTTGCCCGTGGTGAACTTCATTGTATAGGTGCTACAACTCTTGATGAGCACAGA
GAGTATATTGAGAAAGACCCGGCACTTGAAAGACGATTCCAGCCGGTTATGGTTGATGAGCCTACAGTTGAGGATACTAT
CTCAATCCTTAGAGGTCTTAAGGACAGATATGAAGTGTTCCATGGAGTTAAGATTACAGATGGCGCACTTGTAAGTGCAG
CTACTTTGTCAGACAGATATATTTCAGACAGATTCCTGCCAGATAAGGCTATTGACCTTGTAGATGAGGCATGTGCAATG
ATTAAGACTGAACTTGATTCAATGCCTGCCGAACTTGATGAGAAGAGAAGAAAGATTATGCAGCTTGAGATTGAGGAGGC
TGCTCTTAAGAAAGAGACAGATAACCTCAGTAAGGAAAGACTTGATGCATTACAGAAGGAATTATCTGAATTAAGGTCTG
ATTTCAATATCCAGAAAGCTAAATGGGACAGCGAGAAATCTTCTGTTGACCAGGTAAGCAAGTTAAAGGAAGAGATTGAC
CAGATTAATACCCAGATAGCACAGGCTAAGAGAGAATATGATCTTAATAAGGCAGCAGAACTTCAGTATGGTAAACTTCC
ACAGGCACAGAAGGCTTTGGAAGAAGCTGAGAAGAAGTCAAGTAATAGAGATATGAGTCTTGTTCATGAAAGTGTTACTG
AGGAAGAGATTGCCAAGATTATATCAAGATGGACTGGTATTCCGGTTAGCAAGTTAAGTGAGTCTGAAAGACAGAAAACT
CTTAATCTTGATGAACAGCTCCACAAGAGAGTTATCGGTCAGGATGAAGGTGTTACTAAGGTTACAGAGGCAATCATAAG
GTCTAAGGCTGGTATTAAAGACCCGACTAAGCCAATCGGTTCATTCCTGTTCTTAGGACCTACAGGTGTAGGTAAGACAG
AGCTTGCAAAGGCACTTGCTGAGAGTCTGTTTGATGATGAATCTAATATAGTAAGACTTGATATGTCCGAGTATATGGAG
AAGTATTCAGTATCCAGACTTATCGGAGCGCCTCCAGGATATGTAGGTTATGATGAAGGTGGACAGCTTACAGAAGCAGT
AAGAAGAAAACCATATTCAGTTGTTCTTTTTGATGAAGTTGAGAAAGCACATCCAGATGTATTTAATGTCCTCTTACAGG
TACTTGATGATGGCCGTATCACTGATTCACAGGGAAGAACTGTGGATTTTAAGAACACTATAATCATAATGACAAGTAAC
ATTGGTTCTTCATATCTGCTTGAAGGCATCAATCCTGATGGCTCAATTAAGCCAGAGGCAGAGGAAGCTGTTATGGGTGA
TTTAAAGAATCATTTCAGACCTGAATTCCTTAATCGTCTTGATGAGATAATTATGTTCAAGCCTCTTACTAAGGATAATA
TCAGCAATATTATCAATCTTCTTGTTGCAGATGTTAACAAGAGACTTGCAGATAAAGAGCTTGAGATTGTTCTTACAGAT
GCAGCCAAGGATTTCATAGTTGAAAACGGATTTGACCCAATGTATGGTGCAAGACCGCTTAAGAGATATGTCCAGAAGAC
AGTTGAGACACTGGCAGCCAAGTTAATACTTGCAGGCAATATCAATACAGGGGATGATATTGTTATTGACCTTGTAGATG
GAAAGCTGACAGCCAGAGCCGCTGCAAGACAGAAATAA

Protein sequence :
MNINKFTQKSIEAVNQCEKIAYDYGNQEIDQEHFLYSLLTIEDSLIASLIEKMGIDKDTFIKNIETLLSQKNKVSGNVQL
YVSNDLNKVLVNAEDEAKRMGDAYVSVEHLMLAMIAAPNKGIKQLFKTYGINRESFLSALATVRGNQSVTSDNPEATYDT
LSKYATDLVERAKDGKLDPVIGRDNEIRNVIRILSRKTKNNPVLIGEPGVGKTAVVEGLAQRIVRGDVPEGLKDKKLFAL
DMGALVAGAKYRGEFEERLKAVLDEVKKSEGQIILFIDEIHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLDEHR
EYIEKDPALERRFQPVMVDEPTVEDTISILRGLKDRYEVFHGVKITDGALVSAATLSDRYISDRFLPDKAIDLVDEACAM
IKTELDSMPAELDEKRRKIMQLEIEEAALKKETDNLSKERLDALQKELSELRSDFNIQKAKWDSEKSSVDQVSKLKEEID
QINTQIAQAKREYDLNKAAELQYGKLPQAQKALEEAEKKSSNRDMSLVHESVTEEEIAKIISRWTGIPVSKLSESERQKT
LNLDEQLHKRVIGQDEGVTKVTEAIIRSKAGIKDPTKPIGSFLFLGPTGVGKTELAKALAESLFDDESNIVRLDMSEYME
KYSVSRLIGAPPGYVGYDEGGQLTEAVRRKPYSVVLFDEVEKAHPDVFNVLLQVLDDGRITDSQGRTVDFKNTIIIMTSN
IGSSYLLEGINPDGSIKPEAEEAVMGDLKNHFRPEFLNRLDEIIMFKPLTKDNISNIINLLVADVNKRLADKELEIVLTD
AAKDFIVENGFDPMYGARPLKRYVQKTVETLAAKLILAGNINTGDDIVIDLVDGKLTARAAARQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-108 41
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 1e-105 41
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 9e-106 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EUBELI_01260 YP_002930704.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2076 Protein 7e-125 44
EUBELI_01260 YP_002930704.1 ATP-dependent Clp protease ATP-binding subunit ClpB VFG2084 Protein 1e-115 43