Gene Information

Name : nanK (BWG_2923)
Accession : YP_002928119.1
Strain : Escherichia coli K-12
Genome accession: NC_012759
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : -
Position : 3254645 - 3255520 bp
Length : 876 bp
Strand : -
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGACCACACTGGCGATTGATATCGGCGGTACTAAACTTGCCGCCGCGCTGATTGGCGCTGACGGGCAGATCCGCGATCG
TCGTGAACTTCCTACGCCAGCCAGCCAGACACCAGAAGCCTTGCGTGATGCCTTATCCGCATTAGTCTCTCCGTTGCAAG
CTCATGCGCAGCGGGTTGCCATCGCTTCGACCGGGATAATCCGTGACGGCAGCTTGCTGGCGCTTAATCCGCATAATCTT
GGTGGATTGCTACACTTTCCGTTAGTCAAAACGCTGGAACAACTTACCAATTTGCCGACCATTGCCATTAACGACGCGCA
GGCCGCAGCATGGGCGGAGTTTCAGGCGCTGGATGGCGATATAACCGATATGGTCTTTATCACCGTTTCCACCGGCGTTG
GCGGCGGTGTAGTGAGCGGCTGCAAACTGCTTACCGGCCCTGGCGGTCTGGCGGGGCATATCGGGCATACGCTTGCCGAT
CCACACGGCCCAGTCTGCGGCTGTGGACGCACAGGTTGCGTGGAAGCGATTGCTTCTGGTCGCGGCATTGCAGCGGCAGC
GCAGGGGGAGTTGGCTGGCGCGGATGCGAAAACTATTTTCACGCGCGCCGGGCAGGGTGACGAGCAGGCGCAGCAGCTGA
TTCACCGCTCCGCACGTACGCTTGCAAGGCTGATCGCTGATATTAAAGCCACAACTGATTGCCAGTGCGTGGTGGTCGGT
GGCAGCGTTGGTCTGGCAGAAGGGTATCTGGCGCTGGTGGAAACGTATCTGGCGCAGGAGCCAGCGGCATTTCATGTTGA
TTTACTGGCGGCGCATTACCGCCATGATGCAGGTTTACTTGGGGCTGCGCTGTTGGCCCAGGGAGAAAAATTATGA

Protein sequence : 
MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDALSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNL
GGLLHFPLVKTLEQLTNLPTIAINDAQAAAWAEFQALDGDITDMVFITVSTGVGGGVVSGCKLLTGPGGLAGHIGHTLAD
PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGADAKTIFTRAGQGDEQAQQLIHRSARTLARLIADIKATTDCQCVVVG
GSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHDAGLLGAALLAQGEKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 5e-38 54
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 1e-26 41
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 1e-26 41
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 8e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nanK YP_002928119.1 N-acetylmannosamine kinase VFG1115 Protein 4e-27 41