Gene Information

Name : pykF (HDEF_0803)
Accession : YP_002923677.1
Strain : Candidatus Hamiltonella defensa T5A
Genome accession: NC_012751
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 801073 - 802485 bp
Length : 1413 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAAAAAACTAAAATTGTTTGCACTATCGGTCCTAGCAGCGAATCAGAAGAGATGTTAGTGCAGTTACTTAATGCAGG
TATGAATGTCATGCGCCTGAATTTTTCGCATGGTGACCACAATGAGCACCTACAACGTATCAAAAATTTGCGAGCCGTTA
TTAAAAAGACAAATCAAAAAGCGGCGATTTTACTGGATACTAAAGGCCCTGAAATTCGCACAAAGGAACTGAAGGGAGGA
AAAGAGGTTTCTTTATCTATAGGTCAAACCTTCACGTTCACGACCGATCAAAATATCATCGGTGATGCTCATACTGTGGC
GGTCACTTACCCTGGATTTGCAAATGATTTAAAAGCCGGCGATACCGTGTTAGTCGATGATGGTTTGCTCGCCATGGAGG
TAATAGAGACCCAAAAAAATGCCGTGATCTGTAAGGTACAAAATAATGGGGATTTAGGCGAAAACAAAGGAGTGAATTTA
CCCGGAATTTCTATTAAATTGAATGCCCTAACTGAAAAAGATAAAGAAGATTTGATATTTGGTTGTCAACATTCTGTTGA
TTTCGTCGCCGCTTCTTTTGTTCGAAAAGCGTCTGATGTATTAGAAATACGCGAATTCTTAAATAAAAATAAGGGAGAAG
GTATTCAAATCATTTCTAAAATTGAAAATGAAGAAGGTCTCAATAACTTCGATGAAATTTTGGCTGTTTCTGATGGCATT
ATGGTCGCTCGTGGCGATTTGGGTGTTGAGATACCTGTCGAAGAAGTAATTTTTGCACAAAAGATGATGATTGAAAAATG
CAATCGGGCTCGAAAAGTGGTCATTACGGCGACTCAAATGCTTGATTCCATGATTAAAAATCCTCGTCCCACTCGTGCTG
AAGCAGGCGATGTCGCGAATGCGATCGTAGACGGAACGGATGCGGTAATGCTATCGGGTGAAAGTGCCAAAGGGAAATAT
CCGATAGAATCCGTAAAAATTATGGCCAGTATTTGTAAACGAACCGATCTGGTTATGCAAAGCCGGATTGATTTTTTGAA
TGAAAATCAAGAAATCAGGATCACAGAGGCGATTTGTCGGAGTGCTGTGGAAACCGCTGAAAAATTAAATGCTCACTTGA
TTATTGTGGCGACCAGTGGTGGAAAATCCGCAAAATCAGTGCGGAAATATTTTCCACATGCGATGATAATGGCATTAACA
ACAAATGAAGTGACAGAAAGGCAGCTGATTTTAACAAAAGGGGTATTTCCTTTTCTGGTTAAAAAAATTGATTCTACGGA
TGATTTTTATCATATCGGTAAAAAAAAGGCGCTAGAACAAAAATTGGCCTGTAAAGGAGATGTCGTGATTATGGTGTCAG
GAGCACTCGTACCCAGTGGTACAACCAACACGGTTTCTGTTCAAGTATTATAA

Protein sequence :
MKKTKIVCTIGPSSESEEMLVQLLNAGMNVMRLNFSHGDHNEHLQRIKNLRAVIKKTNQKAAILLDTKGPEIRTKELKGG
KEVSLSIGQTFTFTTDQNIIGDAHTVAVTYPGFANDLKAGDTVLVDDGLLAMEVIETQKNAVICKVQNNGDLGENKGVNL
PGISIKLNALTEKDKEDLIFGCQHSVDFVAASFVRKASDVLEIREFLNKNKGEGIQIISKIENEEGLNNFDEILAVSDGI
MVARGDLGVEIPVEEVIFAQKMMIEKCNRARKVVITATQMLDSMIKNPRPTRAEAGDVANAIVDGTDAVMLSGESAKGKY
PIESVKIMASICKRTDLVMQSRIDFLNENQEIRITEAICRSAVETAEKLNAHLIIVATSGGKSAKSVRKYFPHAMIMALT
TNEVTERQLILTKGVFPFLVKKIDSTDDFYHIGKKKALEQKLACKGDVVIMVSGALVPSGTTNTVSVQVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-175 77
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-175 77
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-175 77
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 5e-174 76

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_002923677.1 pyruvate kinase VFG0479 Protein 2e-175 77