Gene Information

Name : siiD (HDEF_1961)
Accession : YP_002924695.1
Strain : Candidatus Hamiltonella defensa T5A
Genome accession: NC_012751
Putative virulence/resistance : Virulence
Product : type I transport system, membrane permease HylD family
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1566
EC number : -
Position : 1793531 - 1794805 bp
Length : 1275 bp
Strand : +
Note : COG0845

DNA sequence :
ATGAACAGGAAACAAACTGACACCCTGATGATGATGATGATAATGAGCCTGATCATTATCATCGCCGCTTCTATTATCAA
AGTAAATTCGGTGATTCATGGCCAAGGCATGATAACGAACCGTGATAACACTCAATTTATTTCCTTATCAAAAGGCGGCG
TGATTGAGAAAATCTATGTTTCAGAAGGGGAAAGCGTTAAAAGGGGCGCTCTCCTTGCTAAAGTGATCAACCTCGATTTA
AGAAAGGAATATGAACGATTAAAAGCCCAGAAAGCATTTTTAGTGAAAGACATTGAGGAGCTGACGTCGCTTTTAAATAA
GAATGCGGTAGAAGATTTTTCTGCGTGGCAAGACATCAGCTTAATAAAAAATAAAGAGTTGTCAGCGAATATTGAATTAG
TGAAAAGTCAAATTCATACGAAAACGCTCAAGCTGGGTTCGCTTGAATCTGAAATTACGGGGATGAAAATGCAACTGAAA
GGGAAAAAAGAACAGGTTGCACTTCTGGGTGAAGAGGTGGATATATTGCACCCTTTGGTAAAAAAAGGGATCACGTCGTA
TACGAATTATCTGAATAAAAAGCAGGCATTTATTAAGTTAAAATCAGAGATGGACGAGACGGAAAATAACATTATTTTAA
AAAAAAATGACAGTCATTTAGTGAAAAATGAAATTCGAGCCCTGGATAACGAATTACGGCTGTCATTATCCCGTCAACTG
TCAAAAGATCAGCAAGAGCTGAATTTGATGAGCACGCCGTTAAAAATTTTTGAGCAACAAATAGAGGAAGAAAATGTTCG
AGCTCCGGTCAATGGGGTGATTTATAAAATTAATAAAAGCGCTTCAACTCAAGGGGGGGTTATCCAGGCGGCAGATCTGT
TATTCGAGATCAAACCTTCGGTCAATACCATGCAAGCAGAGATAAAAGTGAATCCTAAATATCGTGATCAACTCTATGTA
GGTGAACAGGCGCTGGTGGATATCTTGTCTCTGGTGAAAGCCAAGGGGAAATTTTATCAAGCCAGCATTGAAAAAATCAG
CCCGGATTCTTACGAGGAGAACACAAATGGGAGTGTGCAGCGTTATTACAAAGTCATCATTAGTTTTAATGTCAAAAATG
AAGACATGGATTGGTTAAAACCTGGTATGGCGGTTGATGCCAGAGTGGTGACAGGAAAACACTCGATTATGTCCTATCTT
ATTTCACCTTTAACAAAAGGAATCAGTCATGTTTTCTCAGAACCGGTACATTTAACGCAATATAACAAACCTTAA

Protein sequence :
MNRKQTDTLMMMMIMSLIIIIAASIIKVNSVIHGQGMITNRDNTQFISLSKGGVIEKIYVSEGESVKRGALLAKVINLDL
RKEYERLKAQKAFLVKDIEELTSLLNKNAVEDFSAWQDISLIKNKELSANIELVKSQIHTKTLKLGSLESEITGMKMQLK
GKKEQVALLGEEVDILHPLVKKGITSYTNYLNKKQAFIKLKSEMDETENNIILKKNDSHLVKNEIRALDNELRLSLSRQL
SKDQQELNLMSTPLKIFEQQIEEENVRAPVNGVIYKINKSASTQGGVIQAADLLFEIKPSVNTMQAEIKVNPKYRDQLYV
GEQALVDILSLVKAKGKFYQASIEKISPDSYEENTNGSVQRYYKVIISFNVKNEDMDWLKPGMAVDARVVTGKHSIMSYL
ISPLTKGISHVFSEPVHLTQYNKP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STM4260 NP_463125.1 cation efflux pump Not tested SPI-4 Protein 7e-121 59
spi4_D AAC26642.1 HLYD family secretion protein Virulence SPI-4 Protein 5e-121 59
siiD CAE11796.1 putative type-I secretion protein, putative inner membrane component Virulence SPI-4 Protein 5e-121 59
STY4457 NP_458557.1 putative type-I secretion protein Not tested SPI-4 Protein 3e-120 59
SC4139 YP_219126.1 membrane permease, cation efflux pump Not tested SPI-4 Protein 7e-121 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
siiD YP_002924695.1 type I transport system, membrane permease HylD family VFG0580 Protein 3e-121 59