Gene Information

Name : folA (HDEF_1626)
Accession : YP_002924386.1
Strain : Candidatus Hamiltonella defensa T5A
Genome accession: NC_012751
Putative virulence/resistance : Resistance
Product : dihydrofolate reductase type I, trimethoprim resistance
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0262
EC number : -
Position : 1479408 - 1479893 bp
Length : 486 bp
Strand : +
Note : COG0262

DNA sequence :
ATGATCATCAGTTTAATTGCCGCCATGGCTCAGAATCGTGTGATTGGCTTGAATAATAAGATGCCATGGCATCTCCCTCT
TGATTTTGCGTGGTTTAAAAAAAATACCCTTCACAAACCTGTTATTATGGGGCGTAAAACTTTCGACTCTCTAGGGCGAG
CTTTGCCTGGGCGGATGAATATTGTGATGACCCGCCAAGGGATTGCCTCTCCAGGAGTGATAGGGGTTTCTTCGATGGAA
AAAGCATTAAAAGCGGCTCAGGATGCCCCTGAAGTCATGGTGATTGGAGGCGCTGAAATTTATCGTCAATTTTTACCTCA
AGCGAATCGTCTTTACCTCACTGAGGTTTTAAAAAATATCCAAGGTGATACTTATTTTCCTGAATATGAACAACAACAGT
GGGAAATGGTATTTCAAGAATCTCATTCTCCCGATAATAGTCATCTTTATTCTTTTTCCTTTCAAATTTTGCACAGAGTA
AGATGA

Protein sequence :
MIISLIAAMAQNRVIGLNNKMPWHLPLDFAWFKKNTLHKPVIMGRKTFDSLGRALPGRMNIVMTRQGIASPGVIGVSSME
KALKAAQDAPEVMVIGGAEIYRQFLPQANRLYLTEVLKNIQGDTYFPEYEQQQWEMVFQESHSPDNSHLYSFSFQILHRV
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dfrA12 ACF06156.1 dihydrofolate reductase Not tested Tn5036-like Protein 1e-21 41