Gene Information

Name : cvrA (HDEF_0016)
Accession : YP_002922941.1
Strain : Candidatus Hamiltonella defensa T5A
Genome accession: NC_012751
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 13264 - 15036 bp
Length : 1773 bp
Strand : -
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
ATGATCTTGAATGCCATCACTATTAATAATCTTTTTTTGATTGGCTCCATATTGGTGGGAACGAGTATTTTATTAAGTTC
CTTATCCTCTCGTCTGGGCATCCCTATTCTGGTTATTTTTCTTGCTATTGGCATGCTGGCAGGGGGAGAAGGTGTGGGAG
GTATCGCTTTTGATAATTATCCCATCGCTTATCTGATCAGCAACCTGGCATTAGCAGTTATTTTGCTTGATGGAGGTATG
CGAACACGCGCCTCTTCATTTCGTGTAGCACTTTGGCCTGCTTTATCACTTGCCACTGTGGGCGTCATGATCACCACAAG
TTTAACGGGTGTTATGGCTGCTTGGCTTTTTCATTTAGATATTATTCAGGGTTTGTTGATAGGAGCCATTATCGGATCTA
CCGATGCCGCGGCCGTGTTTTCATTATTAGGGGGCAAAGGCCTTAATGAACGTGTGAGTGCCACTCTTGAAATTGAATCC
GGCAGTAATGATCCGATGGCGGTTTTTTTGACGATAACTTTAATATCCATGATCTCCAATGGGCAAACTCATTTAGACTG
GATGTTTTTAGTTGATTTATTACAGCAATTTGGTCTTGGGATCCTGATAGGCTTAGGAGGAGGAAGGTTATTATTGCTCC
TTATTAACCGAATGAACCTTGCTAATGGGCTTTATCCTTTATTAGCGCTGGCAGGAGGACTGGTGACTTTTTCTTTAACG
ACCTCTATGAATGGCAGCGGAATTTTATCTGTTTATCTTTGTGGTCTGGTGTTGGGGAATCGCCCTATTCGTAACCGTTT
CGGTATACTCCATACTTTAGACGGACTGGCATGGTTAAGCCAAATCGGTATGTTTTTAGTATTGGGTTTATTAATCAATC
CAACAGATTTAATCACAATTGCGATTCCGGCGTTGCTGTTGTCTCTTTGGATGATTTTGTTTGCCCGCCCTCTTTCTGTT
TTTATTGGATTACTTCCTTTTCATAGTTTTAATTTTCGTGAGCGTATTTTTATTTCTTGGGTAGGATTAAGGGGTGCTGT
GCCCATTATTCTCGCTGTTTTCCCCATGATGGCAGGGTTGGCGAATGCACATTTATTTTTCAATGTCGCCTTTTTCATTG
TGTTAATCTCCTTGTTGGTACAAGGTAGCACTCTTTCGTTTGCTGCACGTAAAACCAAATTAGTGGTACCTCCTCGATTG
GCGCCGATTTCCCGTGTTGGATTAGATATCGATATTAACAATGAATGGGAACAATTTACGTATCAGCTCAGTTCGGACCA
ATGGTGTGTCGGTGCTGCTTTACGTGATTTAGAGATGCCGGAAGGTACCAGAATTTCAGGGCTTTTTCGTGACAAAAATC
TGCTTCATCCTACAGGGAGCACCCGTTTGAAGGACGGAGATATTTTATGTGTGATAGGACATGAACGTGATCTCCCTGCT
CTGGGTAAGCTTTTCAGTCATACCCCTCGTGTTCAGATTGATGAAAGGTTCTTTGGTGATTTCATTCTTGATGCTGATGC
AAAATTAGAAGAAATTTCTCGTATTTATGGATTAAATTTAGAAAAAGTCGCTGACCAACAAAAGAGTTTAGGCGAATTTG
TGATCTATTTACTTGAAAAGGAGCCAGTGATAGGTGATCAAATAAATTGGGACGGATTAACCTGGACCATTGCTGAAATG
GAATCTCAACGAGTGAGTAAAGTAGGCATAAAAATAATGAGAGATAAAAAAAGATCAAAAATTTCAGATGAATCTACCAA
ACCGATAAATTAA

Protein sequence :
MILNAITINNLFLIGSILVGTSILLSSLSSRLGIPILVIFLAIGMLAGGEGVGGIAFDNYPIAYLISNLALAVILLDGGM
RTRASSFRVALWPALSLATVGVMITTSLTGVMAAWLFHLDIIQGLLIGAIIGSTDAAAVFSLLGGKGLNERVSATLEIES
GSNDPMAVFLTITLISMISNGQTHLDWMFLVDLLQQFGLGILIGLGGGRLLLLLINRMNLANGLYPLLALAGGLVTFSLT
TSMNGSGILSVYLCGLVLGNRPIRNRFGILHTLDGLAWLSQIGMFLVLGLLINPTDLITIAIPALLLSLWMILFARPLSV
FIGLLPFHSFNFRERIFISWVGLRGAVPIILAVFPMMAGLANAHLFFNVAFFIVLISLLVQGSTLSFAARKTKLVVPPRL
APISRVGLDIDINNEWEQFTYQLSSDQWCVGAALRDLEMPEGTRISGLFRDKNLLHPTGSTRLKDGDILCVIGHERDLPA
LGKLFSHTPRVQIDERFFGDFILDADAKLEEISRIYGLNLEKVADQQKSLGEFVIYLLEKEPVIGDQINWDGLTWTIAEM
ESQRVSKVGIKIMRDKKRSKISDESTKPIN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 3e-160 71
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 3e-160 71