Gene Information

Name : sicA (HDEF_1510)
Accession : YP_002924282.1
Strain : Candidatus Hamiltonella defensa T5A
Genome accession: NC_012751
Putative virulence/resistance : Virulence
Product : type III secretion chaperone
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2956
EC number : -
Position : 1383030 - 1383548 bp
Length : 519 bp
Strand : +
Note : COG0457

DNA sequence : 
ATGAGTGTAATACGAGATATTAATCAAAAAAAAATATTAGAAATAGATGATGAAACAGCAGAAATGCTGTCTGATGCGAT
TATAAATTCAGCGTCTTTAAAAGATATTCATAATATTCCTGAAGAAATGATGGAGGGATTATATGCTTACGCTTACGATT
TTTATCAAAAAGGAAAACTGGATGAAGCAGAAACATTCTTTCGGTTTTTGTGCATGTATGACCTTTATAATTCTGATTAT
TTCGTCGGGCTCGCGGCCGTCTATCAATTAAAAAAACAATTCAAAAAAGCCATCGATTTATACGCTATCGCGTTTGCATT
AAATAAAACCTCTGATTACAAAATTGTCTTTTTGAGTGGCCAGTGTCAATTATTCATGGGCAAACCCAGACAAGCCAAAC
TCTGTTTTGAATTAGTGTATGAAAAAATAGAAGATCAATTCATACGAAAAAAAGCAAAAGCGTATTTAGACACCATGCAA
AAAATAAAATCTAAAAAAACAGCCACACAGGAGGCATAA

Protein sequence : 
MSVIRDINQKKILEIDDETAEMLSDAIINSASLKDIHNIPEEMMEGLYAYAYDFYQKGKLDEAETFFRFLCMYDLYNSDY
FVGLAAVYQLKKQFKKAIDLYAIAFALNKTSDYKIVFLSGQCQLFMGKPRQAKLCFELVYEKIEDQFIRKKAKAYLDTMQ
KIKSKKTATQEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sicA YP_217805.1 surface presentation of antigens; secretory proteins Virulence SPI-1 Protein 3e-43 58
spaT NP_457280.1 unknown function Virulence SPI-1 Protein 3e-43 58
spaT NP_806489.1 hypothetical protein Virulence SPI-1 Protein 3e-43 58
sicA NP_461807.1 secretion chaperone Virulence SPI-1 Protein 3e-43 58
sycB AAS66850.1 SycB Not tested SSR-1 Protein 7e-28 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sicA YP_002924282.1 type III secretion chaperone VFG0547 Protein 8e-44 58
sicA YP_002924282.1 type III secretion chaperone VFG0988 Protein 2e-39 55
sicA YP_002924282.1 type III secretion chaperone VFG2451 Protein 8e-40 48
sicA YP_002924282.1 type III secretion chaperone VFG1769 Protein 8e-35 48