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Name : spaS (HDEF_1509) Accession : YP_002924281.1 Strain : Candidatus Hamiltonella defensa T5A Genome accession: NC_012751 Putative virulence/resistance : Virulence Product : surface presentation of antigens protein SpaS Function : - COG functional category : N : Cell motility COG ID : COG1377 EC number : - Position : 1381876 - 1382925 bp Length : 1050 bp Strand : + Note : Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins DNA sequence : ATGTCATCTAATAAAACAGAAAAACCGACCCAAAAAAAATTAAAAGATTCTGCAAAAAAAGGGCAATCTTTTAAAACTAA AGATTTTATTATTGCCTGTTTAATGTTAGCGGGCGTGCAATATTTAATTTCTTTTGCTTCTTTTAGTGAATTAATGTTTC TTTATAAAGAAATTATTTCTTTTAATTTTGAATACGATATTCATCGTTATACGATTTCTGTTTTATCGATTGGATTTAAA ATTTTTTTACCTATTTTATTGCTCTGTATATTTTGCTCCGCCTTACCGAGTTTATTACAAACTGGATTTTTACTAGCGAC TAAAGCCATCAAACTGAATTTAGGCGCACTAAATCCGACTAAAGGATTTAAAAAAATATTCAGCTTACGCACAGCCAAAG ATGCCGTTAAATCTGTTTTATATTTGGGTACTTTTTTTGTTGCAGTCCTAGTGGTTTGGAATACAAAAAGAGGTGTTTTA TTTCAACAATTACATGGCAGCAGCCCTTATGAAATCACGATGGTTTGGGGCCAGCTTTTACAAAGCATATTATGGACCTG CCTGGGATGCATCGTGATTATTTTAATTTTAGATGCCTTGGCAGAATACTTCTTGCACATCAAAGATCTGAAAATGGATA AACAGGAAGTGAAACGTGAAATGAAAGAACAAGACGGAAACCCAGAAATAAAAGGAAGGCGTCGTGAATTACATATGGAA ATACTTTCGGAACAAATTAAATCGGATATTAAAAATTCACAATGTATTATTGCCAACCCAACACATATTGCAGTAGGCAT TTATGTGAATCCAGATACTGTCATGATGCCTTTTATTTCAGTTTTAGAAACGAATCAAAAAGCATTGGCAGTCAGGGCTT ATGCAAAAAAAGTCGGGGTCCCTGTTATTCAAAATATTTCATTAGCCAGAGCAATATATAAAAACAATAATCGCTATTCT TTTGTTCGTATGGATGAATTAGATGAACTCTTAAAATTATTGTTCTGGTTATATGATGTAGAAAGCGAAGGGTATTATAA ATTACTTTAA Protein sequence : MSSNKTEKPTQKKLKDSAKKGQSFKTKDFIIACLMLAGVQYLISFASFSELMFLYKEIISFNFEYDIHRYTISVLSIGFK IFLPILLLCIFCSALPSLLQTGFLLATKAIKLNLGALNPTKGFKKIFSLRTAKDAVKSVLYLGTFFVAVLVVWNTKRGVL FQQLHGSSPYEITMVWGQLLQSILWTCLGCIVIILILDALAEYFLHIKDLKMDKQEVKREMKEQDGNPEIKGRRRELHME ILSEQIKSDIKNSQCIIANPTHIAVGIYVNPDTVMMPFISVLETNQKALAVRAYAKKVGVPVIQNISLARAIYKNNNRYS FVRMDELDELLKLLFWLYDVESEGYYKLL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| spaS | AAS66868.1 | SpaS | Not tested | SSR-2 | Protein | 6e-91 | 62 |
| spaS | NP_806490.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 1e-85 | 60 |
| spaS | NP_461808.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 4e-85 | 60 |
| spaS | NP_457281.1 | secretory protein (associated with virulence) | Virulence | SPI-1 | Protein | 1e-85 | 60 |
| spaS | YP_217806.1 | surface presentation of antigens protein SpaS | Virulence | SPI-1 | Protein | 1e-84 | 59 |
| ECs3721 | NP_311748.1 | surface presentation of antigens protein SpaS | Not tested | LIM | Protein | 6e-61 | 49 |
| ysaU | AAS66849.1 | YsaU | Not tested | SSR-1 | Protein | 1e-54 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| spaS | YP_002924281.1 | surface presentation of antigens protein SpaS | VFG0548 | Protein | 2e-85 | 60 |
| spaS | YP_002924281.1 | surface presentation of antigens protein SpaS | VFG1015 | Protein | 2e-63 | 49 |
| spaS | YP_002924281.1 | surface presentation of antigens protein SpaS | VFG2452 | Protein | 4e-54 | 43 |
