Gene Information

Name : ssaN (HDEF_0128)
Accession : YP_002923049.1
Strain : Candidatus Hamiltonella defensa T5A
Genome accession: NC_012751
Putative virulence/resistance : Virulence
Product : type III secretion system ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : -
Position : 132562 - 133902 bp
Length : 1341 bp
Strand : -
Note : COG1157

DNA sequence :
ATGAGTTTGAATAAAATTCATTTGCCAGATGTCTCACCAGTGAGTGAGCGCCTGAAAAAAAAACTGGCTTTTACGATCCC
TGTACCCAGTGGCGCTGTTTATAGAGGACCGATACTGGATGTTGGACGCACCTTAATCAAGGTGAGTTTACCTGGCGTCA
GAATGGGTGAACTCTGCCGAATAGAGCCGAATCGAATTTTAGCAGAAGTCGTTTCTATTGAACAAAAAACAGCGCTTTTA
TCCCCTTTTTCATCCTGTGATGGCCTTTATGCAGGTCAATGGGTTTCTCCTTTAAAATATTCTCATCAAGTCCCTGTCAG
CATGTCCTTAATGGGGCGTATTCTCAATGGATTAGGTCATCCCATCGATGATGGTCCTGGCTTGGGTTACCATTGGCGTT
CATTAGACAACGCCCCTCCTGATCCTCTGAAGCGTAAACCCATTACAGACCAACTTGTCACAGGTATTCGATCATTAGAC
GCGATATTATCTTGCGGAGAAGGTCAAAGAATCGGGATTTTTGCAGCAGCAGGGGTAGGAAAAAGTACTTTACTTGGGAT
GCTGTGCGATGGCAGTGATGCTGATGTGATGGTATTGGCACTGATTGGAGAACGGGGCCGAGAAGTTCGCGAATTTTTAG
AGCAAGTACTTACCCCTAAAGCCCGACAGCGTACCGTTGTGGTCGTGGCCACCTCAGATCGACCTGCTTTAGAACGCTTA
AAAGGGATTTATACGGCCACCACCATTGCTGAATATTTTCGGGATTGTGGTAAAAAAGTCGTATTAATGGTGGATTCTCT
CACGCGTTATGCCAGAGCCGCGAGAGAAATTGGTTTAGCCGCTGGCGAGCCACCCGCTGCTGGCAGTTTCCCTCCAAGTG
TATTTGCTCAAATGCCGCGTTTACTTGAACGAACAGGAAACAGCGATCTTGGAAGCATTACCGCATTTTATACCGTACTG
GTAGAAGGTGATGACATGAATGAACCTGTTGCTGACGAAGTGCGTTCTCTGCTAGATGGGCACATTATATTATCCAGAAA
ATTAGCCGGAGCGGGTCATTACCCTGCGATTGACATTGCGGCCAGTGTGAGTCGAATTATGCCACAAATAGCCTCTTCCT
GGCACTTGGAAATGGCGCAAAAATTGCGATTCATATTGGCGCGTTATGAAGAAATTGAATTATTGGTACGAGTGGGAGAA
TATCAAAAAGGGCAGGATTTAGAAGCAGATGATGCCTTAAAACGATACCCAGCTGTTTGTAACTTTTTGAAGCAGAAAGG
AGGTGAGCATTGGGCATTAGAAAAAACATTAAAAATGCTCGAACAAACAGTGATCTCGTGA

Protein sequence :
MSLNKIHLPDVSPVSERLKKKLAFTIPVPSGAVYRGPILDVGRTLIKVSLPGVRMGELCRIEPNRILAEVVSIEQKTALL
SPFSSCDGLYAGQWVSPLKYSHQVPVSMSLMGRILNGLGHPIDDGPGLGYHWRSLDNAPPDPLKRKPITDQLVTGIRSLD
AILSCGEGQRIGIFAAAGVGKSTLLGMLCDGSDADVMVLALIGERGREVREFLEQVLTPKARQRTVVVVATSDRPALERL
KGIYTATTIAEYFRDCGKKVVLMVDSLTRYARAAREIGLAAGEPPAAGSFPPSVFAQMPRLLERTGNSDLGSITAFYTVL
VEGDDMNEPVADEVRSLLDGHIILSRKLAGAGHYPAIDIAASVSRIMPQIASSWHLEMAQKLRFILARYEEIELLVRVGE
YQKGQDLEADDALKRYPAVCNFLKQKGGEHWALEKTLKMLEQTVIS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 3e-150 72
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 1e-114 58
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 6e-115 58
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-114 58
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 8e-115 58
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 7e-115 58
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-100 56
escN AAC38383.1 EscN Virulence LEE Protein 5e-104 52
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-102 52
escN CAI43874.1 EscN protein Virulence LEE Protein 8e-103 52
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 1e-102 52
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-102 52
escN AAC31513.1 L0034 Virulence LEE Protein 6e-104 52
escN NP_290268.1 hypothetical protein Virulence LEE Protein 7e-104 52
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 6e-104 52
ECs4568 NP_312595.1 EscN Virulence LEE Protein 7e-104 52
escN AAK26715.1 EscN Virulence LEE Protein 3e-102 51
escN AAL57542.1 EscN Virulence LEE Protein 3e-102 51
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-103 51
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-100 51
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-103 50
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 4e-103 50
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-95 50
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 2e-95 50
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 2e-95 50
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 3e-94 50
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 5e-95 50
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-95 50
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 3e-95 50
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-93 49
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-93 49
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 2e-77 48
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-78 48
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 5e-77 48
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-78 48
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-78 48
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-81 48
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 4e-78 47
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 4e-78 47
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 3e-72 45
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 7e-83 45
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 9e-77 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 2e-77 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 2e-76 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-71 44
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 8e-71 44
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-71 44
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 8e-71 44
invC AAS66861.1 InvC Not tested SSR-2 Protein 5e-73 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-72 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ssaN YP_002923049.1 type III secretion system ATPase VFG0515 Protein 4e-115 58
ssaN YP_002923049.1 type III secretion system ATPase VFG0390 Protein 3e-97 57
ssaN YP_002923049.1 type III secretion system ATPase VFG0192 Protein 6e-98 56
ssaN YP_002923049.1 type III secretion system ATPase VFG0730 Protein 3e-104 52
ssaN YP_002923049.1 type III secretion system ATPase VFG0812 Protein 3e-104 52
ssaN YP_002923049.1 type III secretion system ATPase VFG0048 Protein 1e-99 52
ssaN YP_002923049.1 type III secretion system ATPase VFG2144 Protein 9e-88 50
ssaN YP_002923049.1 type III secretion system ATPase VFG2331 Protein 2e-74 48
ssaN YP_002923049.1 type III secretion system ATPase VFG1254 Protein 1e-85 47
ssaN YP_002923049.1 type III secretion system ATPase VFG2499 Protein 2e-73 47
ssaN YP_002923049.1 type III secretion system ATPase VFG2459 Protein 5e-77 46
ssaN YP_002923049.1 type III secretion system ATPase VFG1778 Protein 5e-69 45
ssaN YP_002923049.1 type III secretion system ATPase VFG0555 Protein 3e-71 44
ssaN YP_002923049.1 type III secretion system ATPase VFG1008 Protein 4e-70 42