Gene Information

Name : fhuC (KP1_1003)
Accession : YP_002917883.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Virulence
Product : iron-hydroxamate transporter ATP-binding subunit
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 983253 - 984050 bp
Length : 798 bp
Strand : +
Note : part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter

DNA sequence :
ATGCAGGAACAGACTCCGCACGCAGAAACCACCTTCGCGCTGGATCGCGTCACTTTCCGTGTGCCTGGCCGCACATTGCT
CCATCCGCTCTCGCTCACCTTCCCGACCGGAAAAGTCACAGGCCTGATCGGCCATAATGGCTCCGGCAAATCGACGTTAC
TGAAAATGCTTGGCCGTCATCAGCCGCCCTCCGCAGGCGAAGTGCTGCTGGACGGGCAGCCGCTGGAGAGCTGGGGCAGC
AAAGCCTTTGCCCGCAAAGTGGCCTATCTGCCGCAGCAGCTGCCGGCGGCCGAAGGTATGACGGTGCGCGAGCTGGTGGC
GATCGGCCGCTATCCATGGCACGGCGCGCTGGGTCGCTTTGGCGCAGCGGACCGTGAGAAAGTAGAAGAGGCGATTGCGC
TGGTGGGGCTGAAGCCGCTCGCTCATCGTCTGGTGGACAGCCTCTCCGGCGGTGAACGCCAGCGGGCGTGGATCGCCATG
CTGGTGGCGCAGGACAGTCGCTGCCTGCTGCTCGATGAACCCACCTCGGCGCTGGATATTGCTCATCAAGTCGATGTTCT
GGCGCTGGTGCATCGTCTCAGCCAGCAGCGCGGCCTGACGGTGATCGCCGTCCTGCACGATATTAATATGGCGGCCCGCT
ATTGCGACTATCTGGTGGCCCTGCGCGGCGGAGAAATGATTGCTCAGGGGACGCCGGCGGAACTGATGCGCAGCGACACT
CTGGAACAGATCTACGGCATCCCGATGGGGATCCTGCCACACCCGGCCGGTGCGGCGCCGGTAAGCTTTGTCTATTGA

Protein sequence :
MQEQTPHAETTFALDRVTFRVPGRTLLHPLSLTFPTGKVTGLIGHNGSGKSTLLKMLGRHQPPSAGEVLLDGQPLESWGS
KAFARKVAYLPQQLPAAEGMTVRELVAIGRYPWHGALGRFGAADREKVEEAIALVGLKPLAHRLVDSLSGGERQRAWIAM
LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQQRGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELMRSDT
LEQIYGIPMGILPHPAGAAPVSFVY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 1e-44 46
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 1e-44 45
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-47 45
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-39 43
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-39 43
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 3e-39 43
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 3e-39 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC YP_002917883.1 iron-hydroxamate transporter ATP-binding subunit BAC0164 Protein 7e-45 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC YP_002917883.1 iron-hydroxamate transporter ATP-binding subunit VFG1042 Protein 7e-45 45
fhuC YP_002917883.1 iron-hydroxamate transporter ATP-binding subunit VFG0925 Protein 2e-45 45