Gene Information

Name : KP1_0634 (KP1_0634)
Accession : YP_002917557.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : putative DNA topoisomerase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 621318 - 623009 bp
Length : 1692 bp
Strand : -
Note : internal ID: KP0634

DNA sequence :
ATGGCCGCGCCGGAGGATTACGATCCGGCGCTGAAACACTGGCGGGCAGAGCATCTGCCGTTTATTCCCCCGGCATGGCG
GCTGGTGATCCGCCCGGAGGTGCGCAAGCAGTTCCGTATCATCGAAAAGCTGCTGAAACAGGCGGATGCAGTGGTGATTG
CCACCGATGCCGACCGCGAAGGCGAAACCATCGCCCGTGAAATTCTGGAGCAATGTCGCTGGCGCGGTCCGGTCCAGCGG
CTGTGGCTGTCGGCACTGGATGACGCCAGTATCCACAAGGCGCTTGCTGCGATGCGATCCGGTGACAGTACGTATCCGCT
GTATCAGGCTGGACTGGCGCGCGCCCGCGCCGACTGGCTGGTCGGCATCAACATGACCCGCGCCTGCACGCTGATGAACC
GGCGGCACAAAGGCGTGCTCTCCGTGGGCCGGGTGCAGACGCCGACCTTACGCCTGGTGGTGGAACGCGACCGGGAGATA
TCCCGCTTCACGCCCCGCCCCTGGTGGCGGGTGGACGCCCGGTTGCATGCTGAGGGCACTACCTTTCTGGCGCAGTGGCA
ACCCGATGGGGTGTACTGTGACGACGAAGGCCGCTGTATCCGTGAATCCGCCGCCCGTGAGGCCACTGCGAGCCTGCAAC
AGGCCGGGACCACGCTGGTACTGGATGTGACCACCCGGCGGGAGAAAACGCCGCCACCGCTGGCCTTCACCCTCAGCGCC
CTGCAGCAGGTCTGCTCAAAACAGTGGGGCATGGGCGCGCAGGAGGTACTGGATATCGCCCAGCGCCTGTATGAAACCCA
TAAGGCCACCACCTATCCGCGCACCGACTGCGGCTGGCTGCCGCTCTCCATGCACACTGAAGCACCGCAGGTTCTGGCGG
CGCTGGTCGCCAGCGACATCTCACTGCAGCCCCTCGCCACGCAACTGAATTTGCAACAACACTCCCGGCTATGGGACGAC
AGCAAAATCACCGCCCACCATGGCATCATCCCGACCCGTAAAACGGTAGATCTGACGCAGATGAATGACAGCGAGCGCAA
GGTTTACGGCCTGGTACGCAGCCATTTTCTGGCGCAGTTTCTGTCGGACCATGAGGTGGATAAAACCGACCTGCGCCTGA
ACTGCGCTGGGGAAACGCTGGCTGCCCGAGGCTCAGTCGTGATTGTCAGCGGCTGGCAACAACTGTTTTTACGCGAGATG
GCAACACATTCACCGGAAGAAACGCAGTCACTTCCCGTCCTGCAACAGGGACAAACCTGCCAGGTGGAACAGGTAGACGT
TCGCGCCCGTCAGACTCAACCGCCGGAGCACTACACCGAAGGGACGCTGATTGCCGCGATGAAAAACGCCGCCCGTTTTG
TCAGCGATGAGCGCTTGAAACAGCGGCTGAAAGAGAACGCCGGTATTGGCACCGAAGCCACCCGCGCCGGGATTATCCAG
ACGCTGCTTAAGCGTGGTTATCTGATTAAGCAACGCCGCTTTCTGTTGGCAACGGATACCGCCAGCGCGCTGATTGACGC
CCTGCCGGAAAAGCTGAAAGATCCGGGCACCACTGCACTGTGGGAGCAGATGCTGGATGACATCGCGACGGGGAAAATGG
GGCTGGAGGCGTTCCTGGTGCAGCAGCAAGAAACCGTTACAGCGCTCACGGCTCAAATAGTCAGAGGCCAGAAAAGTGGC
TCATCAGGTTAG

Protein sequence :
MAAPEDYDPALKHWRAEHLPFIPPAWRLVIRPEVRKQFRIIEKLLKQADAVVIATDADREGETIAREILEQCRWRGPVQR
LWLSALDDASIHKALAAMRSGDSTYPLYQAGLARARADWLVGINMTRACTLMNRRHKGVLSVGRVQTPTLRLVVERDREI
SRFTPRPWWRVDARLHAEGTTFLAQWQPDGVYCDDEGRCIRESAAREATASLQQAGTTLVLDVTTRREKTPPPLAFTLSA
LQQVCSKQWGMGAQEVLDIAQRLYETHKATTYPRTDCGWLPLSMHTEAPQVLAALVASDISLQPLATQLNLQQHSRLWDD
SKITAHHGIIPTRKTVDLTQMNDSERKVYGLVRSHFLAQFLSDHEVDKTDLRLNCAGETLAARGSVVIVSGWQQLFLREM
ATHSPEETQSLPVLQQGQTCQVEQVDVRARQTQPPEHYTEGTLIAAMKNAARFVSDERLKQRLKENAGIGTEATRAGIIQ
TLLKRGYLIKQRRFLLATDTASALIDALPEKLKDPGTTALWEQMLDDIATGKMGLEAFLVQQQETVTALTAQIVRGQKSG
SSG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 8e-146 53
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 6e-146 53
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 8e-146 53
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-135 53
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-140 53
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 5e-141 53
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 2e-135 52
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 5e-142 51