Gene Information

Name : pepA (KP1_0546)
Accession : YP_002917483.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : -
Position : 537352 - 538863 bp
Length : 1512 bp
Strand : -
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTCAGTGTAAAAAGCGGTAGCCCGGAGAAGCAGCGGAGCGCCTGTATCGTGGTCGGCGTCTTTGAACCACGTCG
CCTCTCCCCCATCGCCGAACAACTCGATAAAATCAGCGACGGCTACATCAGCGCCCTGCTGCGTCGCGGCGAGCTGGAAG
GCAAACCTGGCCAGACGTTATTGCTGCACCATGTGCCAAACATTCTGTCTGAGCGCATTCTGCTGATTGGCTGCGGCAAA
GAGCGCGAGCTGGATGAGCGTCAGTATAAGCAGGTCATCCAGAAAACCATCAATACCCTGAATGATACCGGCTCAATGGA
AGCCGTCTGCTTCCTGACCGAGCTGCACGTCAAAGGCCGTAACAACTACTGGAAAGTTCGCCAGGCGGTTGAAACCGCCA
AAGAGACGCTGTACAGCTTCGACCAGCTGAAGACCAACAAAAGCGAGCCGCGTCGCCCGCTGCGTAAAATGGTCTTTAAC
GTGCCGACCCGTCGCGAGCTGACCAGCGGCGAACGCGCCATTCAGCATGGCCTGGCGATTGCCGCCGGCATCAAAGCGGC
GAAAGATCTTGGCAATATGCCGCCGAACATCTGTAACGCCGCCTATCTGGCTTCCCAGGCGCGTCAGCTGGCCGATACCT
ACAGCAAAAACGTCATCACCCGGGTGATCGGCGAACAGCAGATGCGTGAGCTGGGGATGAACGCCTACCTCGCCGTCGGC
AATGGGTCGCAGAACGAGTCGCTGATGTCGGTCATCGAATATAAAGGTAACCCGGCTGAGGACGCGCGCCCTATCGTGCT
GGTCGGTAAAGGCCTGACCTTCGACTCCGGCGGTATCTCCATCAAGCCTGCCGAAGGCATGGACGAAATGAAGTACGACA
TGTGCGGCGCGGCGGCGGTGTACGGCGTGATGCGGATGGTTGCCGAACTGCAGCTGCCGCTGAACGTCATCGGCGTGCTG
GCGGGCTGTGAAAACATGCCTGGCGGCCGCGCCTATCGTCCGGGTGACGTCCTGACCACTATGTCCGGCCAGACGGTGGA
AGTGCTGAACACCGACGCCGAAGGCCGCCTGGTGCTGTGCGACGTCCTGACCTACGTTGAGCGCTTCGAGCCGGAAGCGG
TTATCGACGTGGCGACGCTGACCGGGGCCTGCGTGATTGCTCTCGGCCATCACATCACCGGCCTGATGTCGAACCATAAC
CCGCTGGCCCATGAGCTAATCGGCGCCTCCGAACTGGCGGGCGACCGCGCATGGCGTTTGCCGCTGGCCGACGAGTTCCA
GGATCAGCTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGCCGTCCTGGCGGCGCGATCACCGCCGGCTGTTTCC
TGTCGCGCTTCACCCGCAAGTACAACTGGGCGCACCTCGACATCGCCGGTACTGCCTGGCGTTCCGGTAAGGCCAAAGGC
GCGACCGGTCGTCCGGTGGCGCTGCTGTCGCAGTTCCTGCTCAATCGTGCGGGTTTTAACGGCGAAGAATGA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNILSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADTYSKNVITRVIGEQQMRELGMNAYLAVG
NGSQNESLMSVIEYKGNPAEDARPIVLVGKGLTFDSGGISIKPAEGMDEMKYDMCGAAAVYGVMRMVAELQLPLNVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMSNHN
PLAHELIGASELAGDRAWRLPLADEFQDQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLSQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 1e-88 54
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 1e-88 54