Gene Information

Name : metB (KP1_4685)
Accession : YP_002921242.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Resistance
Product : putative cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 4484447 - 4485595 bp
Length : 1149 bp
Strand : +
Note : internal ID: KP4685

DNA sequence :
ATGTCATCTATCCACACCCTGAGTGTACATAGCGGAACCTTCACCGACAGCCACGGCGCAGTGATGCCGCCGATTTATGC
CACCTCCACTTTTGCTCAGCTAGCGCCGGGGCAGCATACCGGTTATGAATATTCCCGCAGCGGGAATCCCACCCGCCACG
CGCTGGAGACGGCGATCGCCGACCTGGAAAACGGCACGCGCGGCTACGCGTTCGCCTCAGGGCTGGCCGCCATCTCCACC
GTGCTGGAGCTGCTGGATAAGGACAGTCACCTGGTGGCGGTCGATGATGTGTATGGCGGCACTTACCGCCTGCTGGAAAA
CGTTCGCCGCCGTAGCGCTGGTCTGCAGGTGAGCTGGGTGAAACCCGACGACCTGGCGGGAATTGAAGCGGCGATCCGCC
CCGACACCCGCATGATCTGGGTGGAAACGCCCACCAACCCGCTGCTGAAGCTCGCGGATCTCAGCGCCATCGCCGCCATC
GCGCGCCGCCATAACCTGATCAGCGTCGCCGATAACACCTTCGCTTCGCCGGCGATCCATCGCCCGCTGGAGCATGAGTT
TGATATTGTGGTGCACTCCGCGACCAAGTACCTCAACGGCCATTCCGATGTCGTCGCCGGCCTGGCGGTGGTTGGCGATA
ACTCCGAGCTCGCGGAAAAGCTTGGCTATCTGCAGAATGCGGTAGGCGGCGTGCTTGACCCGTTCAGCAGCTTCCTGACG
CTGCGCGGCATCCGTACCCTGGCGCTGCGGATGGAGCGCCACAGCGCGAACGCGCTGCAGCTCGCCGAATGGCTGGAACA
GCAGCCGGAAGTGGAGCGAGTCTGGTTTCCCTGGCTGGCCTCGCACCCGCATCATCAGCTGGCGCGCCGGCAAATGGCCC
TGCCCGGCGGCATGATTTCGGTGGTGGTGAAGGGCGATGAAGGTTACGCCGAGCGCATTATCAGCAAGCTGCGCTGGTTT
ACGCTTGCGGAGAGCCTGGGCGGCGTGGAGAGTCTGGTGAGCCAGCCCTTCAGCATGACCCATGCCTCGATCCCGCTGGA
GAAACGCCTGGCGAACGGTATCACACCGCAGCTGATCCGCCTGTCGGTGGGGATCGAAGATCCTCACGATCTGATTGCCG
ACTGGCAGCAGGCGCTGCGGGCGGAGTGA

Protein sequence :
MSSIHTLSVHSGTFTDSHGAVMPPIYATSTFAQLAPGQHTGYEYSRSGNPTRHALETAIADLENGTRGYAFASGLAAIST
VLELLDKDSHLVAVDDVYGGTYRLLENVRRRSAGLQVSWVKPDDLAGIEAAIRPDTRMIWVETPTNPLLKLADLSAIAAI
ARRHNLISVADNTFASPAIHRPLEHEFDIVVHSATKYLNGHSDVVAGLAVVGDNSELAEKLGYLQNAVGGVLDPFSSFLT
LRGIRTLALRMERHSANALQLAEWLEQQPEVERVWFPWLASHPHHQLARRQMALPGGMISVVVKGDEGYAERIISKLRWF
TLAESLGGVESLVSQPFSMTHASIPLEKRLANGITPQLIRLSVGIEDPHDLIADWQQALRAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-80 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-81 50
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-58 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_002921242.1 putative cystathionine gamma-synthase BAC0207 Protein 1e-64 45