Gene Information

Name : tktA (KP1_4645)
Accession : YP_002921205.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 4446553 - 4448661 bp
Length : 2109 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTACATGACTTGTCGCTTGGGTTACATTGTTCACACTTTTTTCCGGCGTAGCCCAAAACGCGCTCTCGTCAAGTCGTT
AAGGGCATGGCCTTCAACAGTCCGAACTGGAGTCAAAATGTCCTCACGTAAAGAGCTTGCTAACGCTATTCGTGCGCTGA
GCATGGACGCTGTACAGAAAGCCAAATCCGGCCACCCGGGGGCCCCGATGGGTATGGCTGACATTGCCGAAGTGCTGTGG
CGTGATTTCCTGAACCATAACCCGAACAATCCGGCCTGGGCTGACCGTGACCGTTTTGTGTTGTCAAATGGCCATGGTTC
GATGCTGATTTACAGCCTGCTGCACCTCACTGGCTACGATCTGCCGATTGAAGAGCTGAAAAACTTCCGCCAGCTGCACT
CCAAAACCCCGGGTCACCCGGAAGTCGGCTACACCGCAGGCGTGGAAACCACCACCGGTCCGCTGGGCCAGGGTATCGCT
AACGCGGTCGGGATGGCTATCGCCGAGAAAACCCTGGCGGCGCAGTTCAACCGTCCGGGACACGATATCGTCGACCACTA
CACCTACGCCTTCATGGGCGACGGCTGCATGATGGAAGGCATTTCTCACGAAGTGTGCTCCCTGGCCGGTACCCTGAAAC
TGGGTAAACTGGTGGCGTTCTATGATGACAACGGCATCTCCATCGACGGCCACGTTGAAGGCTGGTTCACCGACGACACC
GCGAAACGCTTTGAAGCCTACGGCTGGCACGTGGTGCGCGGCGTGGACGGTCACGACGCTGACGCCATCAAACGCGCGGT
AGAAGAAGCACGGGCGGTCACCGACAAACCGTCCCTGCTGATGTGCAAAACCATCATCGGTTTCGGTTCGCCGAACAAAG
CCGGCACCCACGACTCCCACGGCGCGCCGCTGGGCGACGCCGAAATCGCCCTGACCCGCGAAGCGCTGGGCTGGAAACAC
GCGCCGTTTGACATCCCGTCTGACATCTATGCCCAGTGGGATGCCAAAGAAGCCGGCCAGGCGAAAGAAGCCGCATGGAA
CGAGAAGTTCGCGGCTTACGCCAAAGCCTTCCCGCAGGAAGCAGCCGAATTCACCCGCCGTATGAAAGGCGAGATGCCGT
CTGACTTCGACGCGAAAGCTAACGAGTTCATCGCGAAGCTGCAGGCCAACCCGGCGAAAATCGCCAGCCGTAAAGCCTCG
CAGAACGCCATCGAAGCTTTCGGCCCGCTGCTGCCGGAATTCCTCGGCGGCTCCGCAGATCTCGCGCCGTCCAACCTGAC
CCTGTGGTCTGGCTCTAAGCCGATCAACGAAGACGCTGCCGGGAACTACATCCACTACGGCGTGCGCGAGTTCGGTATGA
CCGCTATCGCCAACGGTATCGCGCTGCACGGCGGCTTCCTGCCGTACACCTCCACCTTCCTGATGTTCGTGGAATACGCG
CGTAACGCGGTACGTATGGCCGCGCTGATGAAACAGCGTCAGGTGATGGTCTACACCCACGACTCCATCGGTCTGGGCGA
AGACGGCCCGACTCACCAGCCGGTAGAGCAGGTGGCTTCCCTGCGCGTGACCCCGAACATGTCCACCTGGCGTCCGTGTG
ACCAGGTGGAATCCGCGATTGCGTGGAAATATGGCGTGGAGCGTCAGGACGGCCCGACCGCGCTGATCCTCTCCCGTCAG
AACCTGGCGCAGCAGGAGCGTACCGCAGAGCAGCTGGCGAACGTGGCCCGCGGCGGTTATGTGCTGAAAGATTGCGCCGG
CCAGCCGGAGCTGATCTTCATCGCCACCGGTTCAGAAGTGGAGCTGGCGGTTGCCGCATGGGACAAACTGACTGCCGAAG
GCGTGAAGGCGCGCGTGGTTTCCATGCCGTCCACCGACGCGTTCGACAAGCAGGATGCGGCTTATCGCGAATCCGTACTG
CCGAAAGCCGTGACCGCGCGCGTTGCCGTGGAAGCGGGTATCGCTGACTACTGGTTCAAATACGTTGGCCTGAACGGCGC
TATCGTTGGCATGACCACCTTCGGTGAGTCTGCGCCGGCTGAGCAGCTGTTCGAGGAGTTCGGCTTCACCGTTGATAACG
TGGTCGCTAAAGCGAAAGCGCTGCTGTAA

Protein sequence :
MYMTCRLGYIVHTFFRRSPKRALVKSLRAWPSTVRTGVKMSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLW
RDFLNHNPNNPAWADRDRFVLSNGHGSMLIYSLLHLTGYDLPIEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGIA
NAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMMEGISHEVCSLAGTLKLGKLVAFYDDNGISIDGHVEGWFTDDT
AKRFEAYGWHVVRGVDGHDADAIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREALGWKH
APFDIPSDIYAQWDAKEAGQAKEAAWNEKFAAYAKAFPQEAAEFTRRMKGEMPSDFDAKANEFIAKLQANPAKIASRKAS
QNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKPINEDAAGNYIHYGVREFGMTAIANGIALHGGFLPYTSTFLMFVEYA
RNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAIAWKYGVERQDGPTALILSRQ
NLAQQERTAEQLANVARGGYVLKDCAGQPELIFIATGSEVELAVAAWDKLTAEGVKARVVSMPSTDAFDKQDAAYRESVL
PKAVTARVAVEAGIADYWFKYVGLNGAIVGMTTFGESAPAEQLFEEFGFTVDNVVAKAKALL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 82
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 68