Gene Information

Name : sitC (KP1_4349)
Accession : YP_002920936.1
Strain : Klebsiella pneumoniae NTUH-K2044
Genome accession: NC_012731
Putative virulence/resistance : Virulence
Product : iron transport system inner membrane permease component
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1108
EC number : -
Position : 4173177 - 4174025 bp
Length : 849 bp
Strand : +
Note : internal ID: KP4349

DNA sequence : 
ATGAGCTGGCTGCTGGAGCCGTTTGGCTATCACTATATGCTCAATGCGATGTGGGTGTCGGCGCTGGTGGGCGGCGTCTG
TGCGTTTCTCTCCTGCTACCTGATGCTCAAAGGCTGGTCGCTGATTGGCGACGCCCTCTCCCACTCGATTGTACCCGGCG
TCGCCGGGGCCTATATGCTCGGCCTGCCTTTCGCGCTCGGCGCATTTCTCTCCGGCGGTCTGGCGGCGGGCAGCATGCTG
TTTTTGCAACAGCGCTCGCGGCTAAAAGAGGATGCCATTATCGGGCTGATCTTCTCCTCCTTCTTCGGGATCGGGCTGTT
TATGGTGTCGCTGAATCCGACGTCGGTGAATATTCAGACCATTATCCTCGGCAATATTCTGGCCATCGCCCCGGAGGATA
TTATCCAGCTGGCGGCGATCGGCTTTATCTCAATGGCGATTCTGCTGCTGAAATGGAAAGACCTGATGGTGACCTTCTTT
GATGAACACCATGCCCGCTCGATTGGCCTGAACACCCGCGGCCTGAAGCTGCTGTTCTTTACCCTGCTGGCCGCCTGCAC
CGTGGCGGCGCTGCAGACCGTCGGCGCCTTTCTGGTCATCTGCCTGGTGGTCACTCCCGGGGCTACCGCGTGGCTGTTAA
CCGATCGCTTCCCGCGCCTGCTGGCTATCGCCGTGTCTATCGGCAGCCTGACCAGTTTCTTCGGCGCCTGGCTCAGCTAC
TATCTCGACGGCGCCACCGGCGGCATTATCGTGGTCGCGCAAACGCTGCTGTTCCTCATCACCTTTATCTTCGCGCCGAA
GCACGGCCTGCTGGCCAGCCGCCGCCGCGCCAGGGAGGCCGCATGCTGA

Protein sequence : 
MSWLLEPFGYHYMLNAMWVSALVGGVCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAYMLGLPFALGAFLSGGLAAGSML
FLQQRSRLKEDAIIGLIFSSFFGIGLFMVSLNPTSVNIQTIILGNILAIAPEDIIQLAAIGFISMAILLLKWKDLMVTFF
DEHHARSIGLNTRGLKLLFFTLLAACTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLAIAVSIGSLTSFFGAWLSY
YLDGATGGIIVVAQTLLFLITFIFAPKHGLLASRRRAREAAC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
sitC NP_457257.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 3e-83 88
sitC NP_806466.1 iron transporter inner membrane protein Virulence SPI-1 Protein 3e-83 88
sitC AAD41067.1 SitC Virulence centisome 63 pathogenicity island Protein 3e-83 88
sitC YP_217783.1 iron transporter: fur regulated Virulence SPI-1 Protein 4e-83 88
sitC NP_461784.1 permease Virulence SPI-1 Protein 4e-83 88
sitD AAD41068.1 SitD Virulence centisome 63 pathogenicity island Protein 1e-35 44
sitD NP_457258.1 Iron transport protein, inner membrane component Virulence SPI-1 Protein 2e-35 44
sitD NP_806467.1 iron transporter inner membrane protein Virulence SPI-1 Protein 2e-35 44
sitD YP_217784.1 iron transporter: fur regulated Virulence SPI-1 Protein 2e-35 44
sitD NP_461785.1 permease Virulence SPI-1 Protein 2e-35 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC YP_002920936.1 iron transport system inner membrane permease component BAC0351 Protein 2e-83 88
sitC YP_002920936.1 iron transport system inner membrane permease component BAC0441 Protein 4e-66 69
sitC YP_002920936.1 iron transport system inner membrane permease component BAC0352 Protein 7e-36 44
sitC YP_002920936.1 iron transport system inner membrane permease component BAC0442 Protein 3e-30 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sitC YP_002920936.1 iron transport system inner membrane permease component VFG0527 Protein 2e-83 88
sitC YP_002920936.1 iron transport system inner membrane permease component VFG0528 Protein 7e-36 44